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Composition with anti-pollution damage effect, preparation method and application

A composition and anti-pollution technology, which can be used in medical preparations containing active ingredients, drug combinations, and cosmetic preparations, etc., and can solve problems such as unsatisfactory anti-pollution damage effects

Active Publication Date: 2021-11-30
INFINITUS (CHINA) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the anti-pollution products on the market usually only focus on one of the methods, and the anti-pollution damage effect is not ideal. Therefore, there is an urgent need for a composition with comprehensive regulation and significant anti-pollution damage effects

Method used

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  • Composition with anti-pollution damage effect, preparation method and application
  • Composition with anti-pollution damage effect, preparation method and application
  • Composition with anti-pollution damage effect, preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Example 1 (1:1:1:1)

[0047] Prepared from the following raw materials in parts by weight:

[0048] 6 parts of rhodiola, 6 parts of galangal, 6 parts of ginkgo biloba and 6 parts of grape seed.

[0049] Preparation method: take rhodiola rosea, galangal, ginkgo leaves and grape seeds, add 70% ethanol, the ratio of solid to liquid is 1:10, extract for 3 hours at 80°C, concentrate by rotary evaporation at 85°C, and dry in an oven at 70°C After drying for 4 hours, the obtained extract extract is the composition of the present invention.

Embodiment 2

[0050] Example 2 (1:2:3:4)

[0051] Prepared from the following raw materials in parts by weight:

[0052] 2.4 parts of rhodiola, 4.8 parts of galangal, 7.2 parts of ginkgo biloba and 9.6 parts of grape seeds.

[0053] The preparation method is the same as in Example 1.

Embodiment 3

[0054] Example 3 (4:3:2:1)

[0055] Prepared from the following raw materials in parts by weight:

[0056] 9.6 parts of rhodiola, 7.2 parts of galangal, 4.8 parts of ginkgo biloba and 2.4 parts of grape seeds.

[0057] The preparation method is the same as in Example 1.

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Abstract

The invention relates to the fields of medicine and cosmetics, in particular to a composition with an anti-pollution damage effect, a preparation method and an application. The composition comprises the following raw materials in parts by weight: 1-24 parts of rhodiola, 1-24 parts of galangal, 1-24 parts of ginkgo leaves and 1-24 parts of grape seeds. It has been verified by experiments that the composition of the present invention can regulate the PAH pathway-related factors caused by benzopyrene and PM2.5 air pollution, reduce the expression of CYP1A1, scavenge free radicals, reduce the level of active oxygen ROS, repair oxidative damage, and inhibit the inflammatory factor IL at the same time ‑1B is produced and reduces the expression of matrix metalloproteinase MMP1, so it can be applied to skin, respiratory tract and lung damage caused by PM2.5 air pollution.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a composition with an anti-pollution damage effect, a preparation method and an application. Background technique [0002] In recent years, the situation of air pollution has become increasingly serious, causing pollution to pose an increasing threat to health. Air pollution endangers the health of the human respiratory system, damages the heart and lung function of the human body, and also causes cumulative damage to the health of the skin, the largest organ of the human body exposed outside. According to authoritative academic research papers, fine particles of smog in the air are adsorbed on the surface of the skin and mucous membranes, leading to a series of problems such as mucous membrane inflammation and skin allergies and aging. With the improvement of people's living standards and the strengthening of health awareness, more and more consumers pay a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9062A61P11/00A61P17/00A61P17/18A61P39/06A61P29/00A61K8/9794A61K8/9789A61K8/9771A61Q19/00A61Q19/08
CPCA61K36/16A61K36/41A61K36/87A61K36/9062A61K2236/333A61K2236/51A61K2800/782A61Q19/00A61Q19/08A61K8/9771A61K8/9789A61K8/9794A61P11/00A61P17/00A61P17/18A61P29/00A61P39/06A61K2300/00
Inventor 刘光荣林凤英车飙
Owner INFINITUS (CHINA) CO LTD
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