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Detection method and system for flora markers and terminal

A detection method and marker technology, applied in the biological field, can solve the problems of information loss, reduce the effectiveness of bacterial markers, and cannot fully reflect the complex relationship of bacterial flora, so as to achieve the effect of improving effectiveness

Active Publication Date: 2019-11-12
SHENZHEN INST OF ADVANCED TECH +1
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Problems solved by technology

[0005] In view of this, the embodiment of the present application provides a detection method, detection system and terminal of flora markers to solve the problem of using only local information of flora when screening effective flora markers in the prior art. In this process, the information is lost, the complex relationship between the flora cannot be fully reflected, and the effectiveness of the screened flora markers is reduced.

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  • Detection method and system for flora markers and terminal
  • Detection method and system for flora markers and terminal
  • Detection method and system for flora markers and terminal

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Embodiment Construction

[0025] In the following description, specific details such as specific system structures and technologies are presented for the purpose of illustration rather than limitation, so as to thoroughly understand the embodiments of the present application. It will be apparent, however, to one skilled in the art that the present application may be practiced in other embodiments without these specific details. In other instances, detailed descriptions of well-known systems, devices, circuits, and methods are omitted so as not to obscure the description of the present application with unnecessary detail.

[0026] It should be understood that when used in this specification and the appended claims, the term "comprising" indicates the presence of described features, integers, steps, operations, elements and / or components, but does not exclude one or more other features. , whole, step, operation, element, component and / or the presence or addition of a collection thereof.

[0027] It shou...

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Abstract

The invention is suitable for the technical field of biology and provides a detection method and system for flora markers and a terminal. The method comprises the steps that flora sample data is acquired; according to representative sequences of strain classifications units, by adopting a system development tree algorithm, the similarity of different strain classifications units is acquired, and acorresponding similarity matrix is obtained; according to sample type markers, the abundance of the strain classifications units to which different strains belong, and the similarity matrix, througha generalized lasso regression algorithm model, a target regression coefficient vector corresponding to a set fitting effect is obtained; the strain classifications units, corresponding to nonzero coefficient elements, in the target regression coefficient vector are determined as target flora markers, and the effectiveness of the screened flora markers is improved.

Description

technical field [0001] The application belongs to the field of biotechnology, and in particular relates to a detection method, a detection system and a terminal of a flora marker. Background technique [0002] In recent years, with the rapid development of DNA sequencing technology, the cost of DNA sequencing has also been reduced year by year. We can more easily explore the health status of human beings through information at the genetic level. However, the data dimension at the genetic level is often very large, and it is difficult to analyze. When making machine learning predictions, it is prone to the curse of dimensionality. Therefore, it is very important to find meaningful features among the features of massive genetic data. [0003] The structure of the flora is very complex, and the detection of effective flora markers is of great significance for us to explore the structure of the flora and the impact of the flora on human health. [0004] In the prior art, when ...

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Application Information

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IPC IPC(8): G16B30/00
CPCG16B30/00
Inventor 陈允文蔡云鹏林淑芳
Owner SHENZHEN INST OF ADVANCED TECH
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