Implementation method of three-cascade molecular combinational circuit based on DNA strand displacement

Abstract

The invention provides an implementation method of a three-cascade molecular combinational circuit based on DNA strand displacement. The implementation method comprises the following steps: researching a DNA strand displacement reaction principle based on DNA strand displacement reaction; respectively designing an AND-OR molecular combinational logic gate, an AND-NOT-OR molecular combinational logic gate and an XOR-XNOR molecular combinational logic gate according to a DNA strand displacement reaction principle; carrying out simulation verification by using Visual DSD (Digital Subscriber Device); an AND-OR molecular combinational logic gate, an AND-NOT-OR molecular combinational logic gate and an XOR-XNOR molecular combinational logic gate are sequentially cascaded to form a three-cascademolecular combinational logic circuit; and carrying out simulation analysis by using a three-cascade molecular combinational logic circuit obtained by Visual DSD software. The dynamic behavior of thecascade molecular combinational logic circuit is verified, and the reasonability of the circuit is proved; and a basic theoretical basis is provided for constructing a more complex logic operation circuit in the future, and the development of the biological computer is promoted, so that the reliability of the logic circuit of the biological computer is improved.

Description

Technical field [0001] The present invention relates to the technical field of DNA strand replacement, in particular to a method for implementing a three-cascade molecular combination circuit based on DNA strand replacement. Background technique [0002] In the current fast-developing computer era, DNA computing combining computers and molecular biology is a new research field. As a new computing tool, DNA has solved many problems, such as the traveling salesman NP problem and the largest group problem. DNA self-assembly is an important supporting technology of DNA nanotechnology, which has the characteristics of predictability and programmability. In the application field, these two characteristics have good development prospects in self-assembly. DNA strand replacement technology also plays a dynamic DNA nanotechnology in the field of biocomputing. DNA strand replacement technology has been widely used in DNA nanomachines, molecular logic circuits, DNA sensors, intelligent dr...

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Problems solved by technology

[0004] Aiming at the technical problem that the existing DNA strand displacement technology cannot realize the cascaded molecular combination circuit, the present invention proposes a realization method of a three-cascade molecular combination circuit based on DNA strand displacement, and constructs three kinds of molecular combination circuits based on the reaction mechanism of strand displacement The logic gates are cascaded in parallel to form a three-cascade molecular combinational logic circuit, and the complex dynamic behavior of the three-cascade molecular combinational logic circuit can be realized through Visual DSD simulation software analysis, which plays a good role in promoting the development of biological computers

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