A Segmented Coding Dual-Core Synchronous Magnetic Resonance Imaging Method

Abstract

The invention discloses a dual-nuclear synchronous magnetic resonance imaging method with segmental encoding, which sets the inspection area, layer thickness, and sampling matrix; in the phase encoding gradient channel GP, firstly applies the first phase encoding gradient, and waits for the nuclear 2 magnetic resonance signal signal After the acquisition is completed, the second phase encoding gradient is applied, and the strength of the first phase encoding gradient is the phase encoding gradient array multiplied by the strength of the second phase encoding gradient. If γ 1 > gamma 2 , the second phase encoding gradient is applied in the opposite direction; otherwise, the second phase encoding gradient is applied in the same direction as the first phase encoding gradient. The invention reconstructs images of two nuclides with the same resolution and one-to-one correspondence of pixel positions, realizes accurate registration of different nuclide images obtained by synchronous imaging of two nuclei, and solves the problem of large difference in layer thickness and FOV of different nuclides .

Description

technical field [0001] The invention relates to the technical field of magnetic resonance imaging, in particular to a dual-nuclear synchronous magnetic resonance imaging method for segment encoding. Background technique [0002] Magnetic resonance imaging (MRI) has been widely used in preclinical research and medical diagnosis. Water exists extensively and densely in organisms, and hydrogen nuclei have high NMR sensitivity, making them the preferred nuclei for imaging of organisms. However, for the observation of life activities and the development of diseases, one of the most basic and important physiological activities is metabolism. Proton nuclei can provide little metabolic information, and sodium ( 23 Na), phosphorus ( 31 P), oxygen ( 17 Nuclei such as O) are directly involved in metabolic activities; in addition, exogenous fluorine ( 19 F) Nanoprobes can obtain molecular target information, which can be used to locate the location of lesions, etc. Therefore, with t...

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Problems solved by technology

[0014] In the process of dual-nuclear simultaneous magnetic resonance imaging, the applied gradient acts on two nuclides at the same time. However, the magnetic spin ratio of different nuclides is an inherent property of the nucleus, and the difference is large. According to the formula (1)(4)(5) It is easy to know that for different nuclides, the same gradient is applied, and the slice thickness and FOV corresponding to the collected signals are different, resulting in different image sizes and resolutions, which is not conducive to the registration and comparison of images of different nuclides.

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