Segmented encoding dual-core synchronous magnetic resonance imaging method

Abstract

The invention discloses a segmented encoding dual-core synchronous magnetic resonance imaging method. The segmented encoding dual-core synchronous magnetic resonance imaging method comprises the stepsthat an inspection region, a layer thickness and a sampling matrix are set; in a phase-encoding gradient channel GP, a first phase-encoding gradient is first applied, a second phase-encoding gradientis applied after the acquisition of a nuclear 2 magnetic resonance signal is completed, the intensity of the first phase of the phase-encoding gradient is the phase-encoding gradient array multipliedby gamma1 / gamma2, the intensity of the second phase-encoding gradient is |1-gamma1 / gamma2|*Gp, and if gamma1 is greater than gamma2, the second phase-encoding gradient is applied in the opposite direction; otherwise the second phase-encoding gradient is applied in the same direction as the first phase-encoding gradient. The reconstructed images of the two nuclides have the same resolution and one-to-one correspondence of pixel positions. The accurate registration of different nuclide images obtained by simultaneous imaging of the two nuclides is realized, and the problems of different nuclidelayer thicknesses and large differences in FOV are solved.

Description

technical field [0001] The invention relates to the technical field of magnetic resonance imaging, in particular to a dual-nuclear synchronous magnetic resonance imaging method for segment encoding. Background technique [0002] Magnetic resonance imaging (MRI) has been widely used in preclinical research and medical diagnosis. Water exists extensively and densely in organisms, and hydrogen nuclei have high NMR sensitivity, making them the preferred nuclei for imaging of organisms. However, for the observation of life activities and the development of diseases, one of the most basic and important physiological activities is metabolism. Proton nuclei can provide little metabolic information, and sodium ( 23 Na), phosphorus ( 31 P), oxygen ( 17 Nuclei such as O) are directly involved in metabolic activities; in addition, exogenous fluorine ( 19 F) Nanoprobes can obtain molecular target information, which can be used to locate the location of lesions, etc. Therefore, with t...

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Problems solved by technology

[0014] In the process of dual-nuclear simultaneous magnetic resonance imaging, the applied gradient acts on two nuclides at the same time. However, the magnetic spin ratio of different nuclides is an inherent property of the nucleus, and the difference is large. According to the formula (1)(4)(5) It is easy to know that for different nuclides, the same gradient is applied, and the slice thickness and FOV corresponding to the collected signals are different, resulting in different image sizes and resolutions, which is not conducive to the registration and comparison of images of different nuclides.

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