Noninvasive optical measurement method of intracranial pressure

A technology for optical measurement, intracranial pressure, applied in the field of biomedicine

Inactive Publication Date: 2020-02-14
INST OF FLUID PHYSICS CHINA ACAD OF ENG PHYSICS
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Problems solved by technology

At present, the clinical standard monitoring of intracranial pressure adopts invasive monitoring methods, but invasive methods have huge risks such as infection, brain tissue damage, and cerebral hemorrhage. When the expected benefits of intracranial pressure monitoring are less than the risks of intracranial pressure monitoring, invasive monitoring However, conventional intracranial pressure monitoring cannot be used, so intracranial pressure monitoring is currently limited to the monitoring of specific critical brain disease patients in the neurological intensive care unit

Method used

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  • Noninvasive optical measurement method of intracranial pressure
  • Noninvasive optical measurement method of intracranial pressure
  • Noninvasive optical measurement method of intracranial pressure

Examples

Experimental program
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Effect test

Embodiment 1

[0047] The inventor verified the feasibility of measuring intracranial pressure by using the cerebral blood flow heartbeat index by changing the intravascular pressure of the forearm tissue:

[0048] Connect the transmitting probe and receiving probe of the near-infrared diffusion correlation spectrometer to the forearm tissue of the human body. By changing the pressure of the probe, the forearm tissue is pressurized, thereby compressing the forearm artery, such as image 3 Indicates the change trend of blood flow with probe pressure, from image 3 It can be seen that as the probe pressure increases, the blood flow pulsatility increases.

[0049]In order to obtain the relationship between the probe pressure and the blood flow heartbeat index, the blood flow is measured and calculated by the near-infrared diffusion correlation spectrometer, and then according to the formula Get the corresponding blood flow heartbeat index under each pressure, and then get the relationship bet...

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Abstract

The invention provides a noninvasive optical measurement method of intracranial pressure, and belongs to the field of a biomedical technology. Near-infrared diffusion correlation spectroscopies are used, cerebral blood flow and heart beat pulsatility indexes are used for realizing measurement of intracranial pressure, and relationship of the intracranial pressure (ICP) and the heart beat pulsatility index PI is ICP=K *PI+b, wherein K and B express correction coefficients. Based on the near-infrared diffusion correlation spectroscopies, the cerebral blood flow (CBFI) change caused by heart beatcan be measured, and through the cerebral blood flow change (CBFI), the cerebral blood flow and heart beat pulsatility index (PI) can be obtained; and a principle that change of the intracranial pressure can cause the cerebral blood flow and heart beat pulsatility index (PI) is adopted, and the cerebral blood flow and heart beat pulsatility index (PI) is used for inversing the intracranial pressure (ICP) and change of the intracranial pressure.

Description

technical field [0001] The invention belongs to the technical field of biomedicine, in particular to a non-invasive optical measurement method of intracranial pressure. Background technique [0002] Monitoring of intracranial pressure is important in the management of neurocritical care patients. According to the level and change waveform of intracranial pressure, it has important reference value for judging intracranial injury, cerebral edema, guiding the application of dehydration drugs, and estimating the prognosis. The "Chinese Expert Consensus on Intracranial Pressure Monitoring in Traumatic Brain Injury" strongly recommends monitoring intracranial pressure in patients with acute severe traumatic brain trauma (GCS3-8 points). The current clinical standard monitoring of intracranial pressure adopts invasive monitoring methods, but invasive methods have huge risks such as infection, brain tissue damage, and cerebral hemorrhage. When the expected benefits of intracranial ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/03A61B5/026
CPCA61B5/0261A61B5/031A61B5/7257
Inventor 王德田朱礼国李泽仁邹逸赵祥杰谭福利
Owner INST OF FLUID PHYSICS CHINA ACAD OF ENG PHYSICS
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