Nano antibacterial emulsion containing tea tree essential oil and preparation method thereof

A kind of technology of tea tree essential oil and nanometer, which is applied in the direction of medical preparations of non-active ingredients, antibacterial drugs, emulsion delivery, etc. It can solve the problems of too fast degradation, short retention time, poor stability and solubility, etc., and achieve the preparation process Simple, increased absorbability, improved stability effects

Inactive Publication Date: 2020-03-24
YANGZHOU UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, due to the volatilization, photolysis and oxidation of plant essential oils, the retention time in the environment is too short and the degradation is too fast to exert its biological activity, which will further reduce the control effect and duration of the preparation to a large extent; Due to its poor stability and solubility and long-term storage, it is easy to deteriorate and is rarely extracted directly.

Method used

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  • Nano antibacterial emulsion containing tea tree essential oil and preparation method thereof
  • Nano antibacterial emulsion containing tea tree essential oil and preparation method thereof
  • Nano antibacterial emulsion containing tea tree essential oil and preparation method thereof

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Embodiment 1

[0030] The emulsion system of the nano antibacterial emulsion containing tea tree essential oil is prepared from tea tree essential oil, emulsifier and water, and the composition of each component is calculated in mass percentage: 1-10% of tea tree essential oil, 1-6% of emulsifier, and Ionized water supplements 100%, and described emulsifier is Tween 80; The preparation method of nano antibacterial emulsion, comprises the following steps:

[0031] (1) Accurately weigh the emulsifier in the ratio, place it in a container, and accurately add the tea tree essential oil in the ratio, stir with a magnetic stirrer at 700r / min for 5min until uniform;

[0032] (2) Accurately weigh the deionized water in the ratio, slowly drop it into the liquid obtained in step (1) with a syringe while stirring, stir at 2000r / min for 2min until uniform, and form a coarse emulsion;

[0033] (3) Take a certain amount of coarse emulsion in a beaker, place it in an ultrasonic cell pulverizer, select a 6m...

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Abstract

The invention discloses a nano antibacterial emulsion containing tea tree essential oil and a preparation method thereof. The nano antibacterial emulsion containing tea tree essential oil is preparedby an ultrasonic emulsification method, an emulsion system is prepared from 1-10% of tea tree essential oil, 1-6% of an emulsifier and water, and the emulsifier is Tween 80. In an antibacterial test,the nano antibacterial emulsion containing tea tree essential oil disclosed by the invention has a better antibacterial effect than unembedded tea tree essential oil, is longer in antibacterial time and has a slow-release effect. The nano antibacterial emulsion containing tea tree essential oil is novel in idea, simple in preparation method and high in practicability, the antibacterial activity ofthe tea tree essential oil is remarkably improved through the nano antibacterial emulsion containing tea tree essential oil, a safe and long-acting antibacterial agent is provided for the fields of food and medicine, and the application prospect is promising.

Description

technical field [0001] The invention belongs to the field of emulsion embedding and antibacterial technology, and in particular relates to a nano antibacterial emulsion containing tea tree essential oil and a preparation method thereof. Background technique [0002] Antibiotics have been the cornerstone of modern medicine since their discovery. Antibiotic resistance occurs when microorganisms such as bacteria become resistant to the drugs used to treat them. The continued overuse and misuse of antibiotics in human and animal health contributes to the emergence and spread of antibiotic resistance. Antibiotic resistance is occurring around the world, and new mechanisms of resistance are emerging and spreading globally, making it harder for a growing number of bacterial infections such as pneumonia, tuberculosis, sepsis, gonorrhea and foodborne illness Treatment, and sometimes no cure. Without urgent action, we will enter a post-antibiotic era where common infections and min...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/107A61K47/26A61P31/04
CPCA61K9/1075A61K47/26A61P31/04
Inventor 魏思敏伯若楠李金贵佘强龙刘明江赵昕
Owner YANGZHOU UNIV
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