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A microfluidic chip flow rate sensor based on micro-nano optical fiber

A microfluidic chip and flow rate sensor technology, applied in fluid velocity measurement, laboratory containers, instruments, etc., can solve problems such as small pressure changes, and achieve the effects of high safety, wide application and good stability

Active Publication Date: 2021-01-15
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the change in pressure is usually very small, how to accurately measure the pressure on the pipe wall has become the biggest problem faced by this method

Method used

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  • A microfluidic chip flow rate sensor based on micro-nano optical fiber
  • A microfluidic chip flow rate sensor based on micro-nano optical fiber
  • A microfluidic chip flow rate sensor based on micro-nano optical fiber

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Embodiment Construction

[0018] Such as Figure 1 to Figure 4 An embodiment of the micro-nano optical fiber-based microfluidic chip flow rate sensor of the present invention is shown, which includes a single-channel microfluidic chip 5, a micro-nano optical fiber and a flexible film 4, and the thickness of the flexible film 4 is less than or equal to 100 μm. The refractive index of the flexible film 4 is smaller than that of the micro-nano optical fiber; the flexible film 4 covers the fluid channel 8 of the microfluidic chip, and the flexible film 4 is respectively provided with openings at the inlet and outlet of the fluid channel 8; the microfluidic chip The stretched part 1 of the micro-nano fiber crosses the fluid channel here at the position to be measured in the fluid channel, so that the tapered transition zones 2 at both ends of the stretched part 1 of the micro-nano fiber are respectively placed in the fluid where the position to be measured is located. sides of the channel. The stretched pa...

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Abstract

The invention discloses a micro-fluidic chip flow velocity sensor based on micro-nano optical fibers. The micro-fluidic chip flow velocity sensor comprises a micro-fluidic chip, micro-nano optical fibers and a flexible thin film, the thickness of the flexible thin film is smaller than or equal to 100 microns, a refractive index of the flexible thin film is smaller than that of the micro-nano optical fiber, the flexible film coats a fluid channel of the micro-fluidic chip, the flexible film is provided with openings at an inlet and an outlet of the fluid channel respectively, a stretching partof the micro-nano optical fiber stretches across the fluid channel at the to-be-measured position of the fluid channel, and the stretching part of the micro-nano optical fiber, a tapering transition area and non-stretching parts at the two ends are partially embedded in the flexible film. When fluid in the fluid channel flows, the flexible film is bent outwards under pressure, and due to the increase of the bending loss of the micro-nano optical fiber, an output light intensity signal is reduced accordingly, so that flow velocity sensing is realized. According to the invention, multi-point flow velocity detection can be realized, flow velocity detection can be carried out on an existing micro-fluidic chip, and high-sensitivity flow velocity sensing is realized.

Description

technical field [0001] The invention relates to a flow rate measuring device for a microfluidic chip, which belongs to the field of optical fiber sensing. Background technique [0002] In the past few decades, microfluidic technology has become an important platform for related scientific research in the fields of fluid physics, microreactors, and biolaser technology. In the research of the above-mentioned fields, it is usually necessary to carry out precise measurement and control on the micro-flow, which makes people have higher and higher demand for high-precision, multi-functional micro-fluidic chip flow rate sensors. At present, microfluidic chip flow rate sensors with complex structure and high integration are mostly used to achieve highly sensitive detection of microflow, but the processing of complex structures requires sophisticated instruments, which increases the cost of the chip; at the same time, complex structures will also pollute samples. , disturbing the mi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): B01L3/00G01P5/26
CPCB01L3/502707G01P5/26
Inventor 张磊张璋
Owner ZHEJIANG UNIV
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