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Drug balloon and use method thereof

A balloon and drug technology, applied in the field of medical devices, can solve the problems of low effective drug release rate, occlusion of distal blood vessels, and affect the treatment effect, so as to avoid distal vascular embolism and acute myocardial infarction, avoid myocardial ischemia, The effect of increasing the effective release rate

Active Publication Date: 2020-06-19
上海脉全医疗器械有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, for traditional drug balloons, most of the drugs are lost during the operation, and the amount of drugs actually acting on the vessel wall is small, and the effective drug release rate is very low, which affects the therapeutic effect.
Finally, the drug coating that falls off during the expansion and release of the traditional balloon is not soluble in blood, and will exist in the form of large particles, and as the blood flows to the small distal blood vessels, there is a great risk of occlusion of the distal blood vessels

Method used

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  • Drug balloon and use method thereof
  • Drug balloon and use method thereof
  • Drug balloon and use method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0085] Such as Figure 1-Figure 6 As shown, the present embodiment provides a drug balloon 10 , including a balloon catheter 100 , and the balloon catheter 100 includes a balloon body section 110 and a fluid-through tube 120 . One end of the balloon body section 110 is connected to the proximal end 1202 of the liquid passage tube, and the other end of the balloon body section 110 is connected to the distal end 1203 of the liquid passage pipe. The liquid cavity 140 is used to pass into the balloon a medicinal liquid for treating diseases, and in this embodiment, the medicinal liquid is preferably a drug microsphere preparation. The surface of the balloon body segment 110 is also provided with a blood flow chamber 130 for blood circulation in the blood vessel during the operation, and the blood flow chamber 130 is formed by surrounding the side walls of the liquid passage chamber 140 . In this embodiment, the shape of the balloon body segment 110 is preferably cylindrical, and ...

Embodiment 2

[0107] Such as Figure 7-Figure 12 As shown, the present embodiment provides a drug balloon 20 , including a balloon catheter 200 , and the balloon catheter 200 includes a balloon body segment 210 and a fluid-through tube 220 . One end of the balloon body section 210 is connected to the proximal end 2202 of the liquid passage tube, and the other end of the balloon body section 210 is connected to the distal end 2203 of the liquid passage pipe. The liquid cavity 240 is used to pass into the balloon a medical solution for treating diseases. In this embodiment, the medical solution is preferably a drug microsphere preparation. The surface of the balloon body segment 210 is also provided with a blood flow chamber 230 for blood circulation in the blood vessel during the operation, and the blood flow chamber 230 is surrounded by the side walls of the liquid passage chamber 240 . In this embodiment, the shape of the balloon body section 210 is preferably cylindrical, and a plurality...

Embodiment 3

[0114] Such as Figure 13-Figure 18 As shown, the present embodiment provides a drug balloon 30 , including a balloon catheter 300 , and the balloon catheter 300 includes a balloon body segment 310 and a fluid-through tube 320 . One end of the balloon body section 310 is connected to the proximal end 3202 of the liquid passage tube, and the other end of the balloon body section 310 is connected to the distal end 3203 of the liquid passage pipe. The liquid chamber 340 is used to pass into the balloon a medical solution for treating diseases, and in this embodiment, the medical solution is preferably a drug microsphere preparation. The surface of the balloon body segment 310 is also provided with a blood flow chamber 330 for blood circulation in the blood vessel during the operation, and the blood flow chamber 330 is surrounded by the side walls of the liquid passage chamber 340 . In this embodiment, the shape of the balloon body section 310 is preferably cylindrical, and a plu...

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Abstract

The invention relates to the technical field of medical instruments, and discloses a medicine balloon and a using method thereof. The medicine balloon comprises a balloon catheter which comprises a balloon body section and liquid passing pipes, wherein two ends of the balloon body section are respectively connected with a liquid passing pipe; the inner cavity of the balloon body section communicates with the liquid passing pipes to form a liquid passing cavity; a blood flowing cavity allowing blood to pass through is also arranged on the surface of the balloon body section and is defined by the side wall of the liquid passing cavity; and micropores for a drug microsphere preparation to pass through are distributed on the outer arc surface of the balloon body section. When the medicine balloon is pressurized, due to the fact that the blood flowing cavity can allow a blood flow in a blood vessel to pass through, sufficient downstream blood supply can be guaranteed, and myocardial ischemia caused by blood vessel plugging is avoided; meanwhile, sufficient contact action time between the surface of a balloon and the inner wall of a blood vessel is guaranteed, so the adhesion effect of adrug on a target blood vessel wall is improved; and the drug microsphere preparation is released to the blood vessel wall through arrangement of the micropores in the balloon body section, so the drug can be more stably and effectively retained on the blood vessel wall and stably released for a long time.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to a drug balloon and a method for using the same. Background technique [0002] Cardiovascular and cerebrovascular diseases have become the number one cause of death in the world. At present, the treatment methods for ischemic heart disease mainly include the following types: drug-based basic treatment, coronary artery bypass grafting-based surgical treatment, coronary stent-based interventional treatment, and drug-balloon-based interventional treatment. The above-mentioned several treatment methods have achieved obvious effects in the treatment of coronary artery stenosis, but each still has some significant problems. [0003] Among them, coronary stent implantation is to deliver the stent system to the target area through puncture and intervention, and the balloon expands to release the stent, open the narrowed and diseased blood vessel, restore the blood supply, and tre...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M25/10A61L29/14A61L29/16
CPCA61M25/1002A61L29/16A61L29/146A61L2300/416A61L2300/602A61M2025/105A61M2025/1097A61L2300/622
Inventor 祁勇翔罗雷聂芳芳李丹唐乃杰缪永生刘瑜
Owner 上海脉全医疗器械有限公司
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