A kind of hydrocolloid antibacterial dressing and preparation method thereof

A hydrocolloid and liquid technology, applied in pharmaceutical formulations, medical preparations containing active ingredients, peptide/protein ingredients, etc., to achieve the effect of being beneficial to local microcirculation and cell metabolism, avoiding adverse stimulation, and being easy to fix

Active Publication Date: 2021-08-31
WENZHOU MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are many types of hydrocolloid dressings available, and each type of hydrocolloid dressing has its own advantages and disadvantages, but no one product has obvious advantages in preventing facial pressure ulcers caused by medical personnel wearing masks and goggles

Method used

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  • A kind of hydrocolloid antibacterial dressing and preparation method thereof
  • A kind of hydrocolloid antibacterial dressing and preparation method thereof
  • A kind of hydrocolloid antibacterial dressing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] A hydrocolloid antibacterial dressing, comprising the following components in terms of mass percentages: 0.5% small molecule silk peptide, 0.8% fish scale collagen, 3% chitosan, 2% propylene glycol, 3% glycerin, 30% polyethylene glycol, The balance is purified water.

[0030] The preparation method of described hydrocolloid antibacterial dressing, comprises the steps:

[0031] (1) Weigh each raw material component by weight, mix polyethylene glycol and purified water, heat to 90°C, stir to dissolve and cool to 40°C, then add small molecule silk peptide, fish scale collagen, chitosan in sequence , propylene glycol and glycerin, after stirring and dissolving, hydrocolloid liquid is obtained;

[0032] (2) Vacuumize and defoam the hydrocolloid liquid in step (1), then pour it into a forming mold, and immediately place it at -10°C for 10 hours to freeze to obtain a freeze-formed hydrocolloid film;

[0033] (3) Vacuum-seal the hydrocolloid film freeze-formed in step (2), th...

Embodiment 2

[0035] A hydrocolloid antibacterial dressing, comprising the following components in terms of mass percentages: 1.0% small molecule silk peptide, 0.2% fish scale collagen, 6% chitosan, 5% sodium hyaluronate, 20% polyvinyl alcohol, and the balance for purified water.

[0036]The preparation method of described hydrocolloid antibacterial dressing, comprises the steps:

[0037] (1) Weigh each raw material component by weight, mix polyvinyl alcohol and purified water, heat to 95°C, stir to dissolve and cool to 42°C, then add small molecule silk peptide, fish scale collagen, chitosan and Sodium hyaluronate, after stirring and dissolving, hydrocolloid liquid is obtained;

[0038] (2) Vacuumize and defoam the hydrocolloid liquid in step (1), then pour it into a forming mold, and immediately place it at -15°C for 6 hours to freeze to obtain a freeze-formed hydrocolloid film;

[0039] (3) Vacuum-seal the hydrocolloid film freeze-formed in step (2), thaw it at room temperature and ste...

Embodiment 3

[0041] A hydrocolloid antibacterial dressing, comprising the following components in terms of mass percentages: 0.8% small molecule silk peptide, 0.5% fish scale collagen, 4% chitosan, 3% allantoin, 10% polyvinylpyrrolidone, carboxymethyl Sodium cellulose 15%, the balance is purified water.

[0042] The preparation method of described hydrocolloid antibacterial dressing, comprises the steps:

[0043] (1) Weigh each raw material component by weight ratio, mix polyvinylpyrrolidone, sodium carboxymethylcellulose and purified water, heat to 92°C, stir to dissolve and cool to 45°C, then add small molecule silk peptide, Fish scale collagen, chitosan and allantoin, stirred and dissolved to obtain hydrocolloid liquid;

[0044] (2) Vacuumize and defoam the hydrocolloid liquid in step (1), then pour it into a forming mold, and immediately place it at -12°C for 8 hours to freeze to obtain a freeze-formed hydrocolloid film;

[0045] (3) Vacuum-seal the hydrocolloid film freeze-formed in...

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Abstract

The invention belongs to the field of medical dressings, in particular to a hydrocolloid antibacterial dressing and a preparation method thereof. The dressing contains components such as small molecule silk peptide, fish scale collagen, chitosan, moisturizing material, skeleton material and purified water. The hydrocolloid antibacterial dressing of the present invention has functions such as sweat absorption, antibacterial properties and emollient properties, conforms to various humanized designs, can prevent related injuries caused by instrumental pressure on the frontal face, and effectively protect the skin safety of medical staff. Cooperating with emollient and antibacterial active ingredients can further enrich the use properties of hydrocolloid dressings, and protect and repair damaged skin in an all-round way.

Description

technical field [0001] The invention belongs to the field of medical dressings, in particular to a hydrocolloid antibacterial dressing and a preparation method thereof. Background technique [0002] During the epidemic, for effective protection, the general population needs to wear masks when going out. In some special positions, such as medical staff, epidemic prevention staff, workshop workers, etc., who need to wear preventive medical devices such as masks and goggles for a long time, the skin is in a state of oppression and airtightness for a long time, and some symptoms may occur. A series of problems, such as: (1) indentation: due to wearing a mask for a long time, the pressure is too high, the blood circulation is not smooth, and deep marks will appear on the pressured part, which will not disappear for a long time; (2) skin infection: due to Wearing a mask and goggles for a long time will cause displacement due to incomplete coordination with the face, resulting in ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/00A61L26/00
CPCA61L26/0023A61L26/0033A61L26/0047A61L26/0061A61L26/0066A61L26/008A61L2300/232A61L2300/404C08L89/00C08L5/08
Inventor 肖健张宏宇许可王梦莹曹慧鑫李校堃
Owner WENZHOU MEDICAL UNIV
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