Adaptive progressive dilator for achalasia and preparation method thereof

Achalasia, self-adaptive technology, applied in dilators, manufacturing tools, welding equipment, etc., can solve the problems of dilation and incision range and degree under endoscopy, gastroesophageal perforation, and affecting curative effect, etc. Achieve the effect of saving time and medical expenses, relieving pain, and having shape memory function

Active Publication Date: 2021-03-02
DONGHUA UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disadvantage of endoscopic treatment is that it is difficult to grasp the scope and degree of dilation and incision under endoscopy. If the scope is insufficient, the curative effect will be affected. If the scope is too large, serious complications such as gastroesophageal perforation and bleeding will easily occur.
(3) Surgical treatment: Laparoscopic sphincterotomy is the most commonly used at present. This operation is effective, but complications such as gastroesophageal reflux disease, esophageal perforation, and bleeding may occur
10% to 15% of patients who have been treated for achalasia will develop advanced or end-stage achalasia, and up to 5% of patients may require esophagectomy, with more serious consequences

Method used

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  • Adaptive progressive dilator for achalasia and preparation method thereof
  • Adaptive progressive dilator for achalasia and preparation method thereof
  • Adaptive progressive dilator for achalasia and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] The self-adaptive progressive dilator for achalasia made of PLA was made by laser engraving method, and it was set at 100°C for 5 minutes, as shown in figure 2 As shown, the prepared self-adaptive progressive dilator includes an integrally formed esophagus, cardia and stomach, wherein the esophagus is an irregular cylindrical structure with a large middle and small ends, and is used to integrate with the human esophagus. The lower part of the inner wall fits; the cardia is a cylindrical structure, used to fit the inner wall of the human cardia; the stomach is a trumpet-shaped structure, used to fit the upper inner wall of the human stomach; the wall of the self-adaptive progressive dilator is porous structure, the porosity is 40%, and the thickness of the wall is 0.5mm;

[0044] The adaptive progressive dilator has shape memory performance. The adaptive progressive dilator is placed on the lesion of the patient through the delivery device. During the delivery process, ...

Embodiment 2

[0046] The self-adaptive progressive dilator for achalasia made of PCL was made by weaving method, and it was set at 58°C for 10 minutes, such as figure 1 As shown, the prepared self-adaptive progressive dilator includes an integrally formed esophagus, cardia and stomach, wherein the esophagus is an irregular cylindrical structure with a large middle and small ends, and is used to integrate with the human esophagus. The lower part of the inner wall fits; the cardia is a cylindrical structure, used to fit the inner wall of the human cardia; the stomach is a trumpet-shaped structure, used to fit the upper inner wall of the human stomach; the wall of the self-adaptive progressive dilator is porous structure, the porosity is 50%, and the thickness of the wall is 0.4mm;

[0047] The adaptive progressive dilator has shape memory performance. The adaptive progressive dilator is placed on the lesion of the patient through the delivery device. During the delivery process, the dilator i...

Embodiment 3

[0049] The self-adaptive progressive dilator for achalasia made of nickel-titanium wire was made by welding method, and it was set at 550°C for 20 minutes, such as image 3 As shown, the prepared self-adaptive progressive dilator includes an integrally formed esophagus, cardia and stomach, wherein the esophagus is an irregular cylindrical structure with a large middle and small ends, and is used to integrate with the human esophagus. The lower part of the inner wall fits; the cardia is a cylindrical structure, used to fit the inner wall of the human cardia; the stomach is a trumpet-shaped structure, used to fit the upper inner wall of the human stomach; the wall of the self-adaptive progressive dilator is porous structure, the porosity is 60%, and the thickness of the wall is 0.3mm;

[0050] The adaptive progressive dilator has shape memory performance. The adaptive progressive dilator is placed on the lesion of the patient through the delivery device. During the delivery proc...

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Abstract

The invention relates to an adaptive progressive dilator for achalasia and a preparation method thereof. The formed cylindrical shape memory material is put on a male mold, and then a female mold is put on the outer surface of the dilator. The self-adaptive progressive dilator for achalasia is prepared by shaping; the prepared self-adaptive progressive dilator is an enlarged part of the treatment model of achalasia; the treatment model of achalasia is uniform in wall thickness Hollow structure, its external shape and size are the same as the shape and size of the inner cavity of the treatment site for achalasia; the enlargement refers to keep the axial size unchanged, and enlarge the radial size in equal proportion; the treatment site for achalasia Including the cardia and the lower end of the esophagus connected to the cardia and the upper end of the stomach; the radial support force per unit length of the self-adaptive progressive dilator is 0.5-15N / mm. The self-adaptive progressive dilator of the invention can be used to treat the achalasia of the cardia, and the effect is remarkable and there is no trauma.

Description

technical field [0001] The invention belongs to the technical field of medical devices, and relates to an adaptive progressive dilator for achalasia and a preparation method thereof. Background technique [0002] Cardiac achalasia, also known as cardia spasm, is a condition in which cardiac sphincter relaxation is caused by dysfunction of the neuromuscular dysfunction of the cardia, and food cannot pass smoothly and stays there, which gradually increases esophageal tension, decreases peristalsis, and dilates the esophagus. disease. The clinical manifestations include dysphagia, substernal pain, food regurgitation, cough and lung infection caused by food regurgitation and inhalation into the trachea. Although uncommon, achalasia has an insidious onset, progressive disease, and is usually present for several years at the time of clinical discovery. [0003] Achalasia can be divided into primary (idiopathic) and secondary types. The etiology of primary achalasia is still unc...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61M29/00B23K26/382B23K31/02
CPCA61M29/00A61M2210/1042B23K31/02B23K26/382A61M2210/005A61F2210/0004A61F2250/0026A61F2250/0028
Inventor 关国平王璐王富军林婧
Owner DONGHUA UNIV
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