Composition for improving liver function damage and application thereof

A technology of composition and liver function, which is applied in the direction of drug combination, medical preparations containing active ingredients, food science, etc., can solve problems such as damage to liver function, liver inflammation, and physical health effects, to eliminate damage, strengthen the liver, Treat or improve the effect of liver inflammation

Inactive Publication Date: 2020-07-24
MEIZHOU GOLDEN POMELO HEALTH TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, eating too much artificial sweeteners, like sugar, will have a certain impact on health, especially disrupting the body's glucose metabolism, causing liver inflammation, and damaging liver function, etc.

Method used

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  • Composition for improving liver function damage and application thereof
  • Composition for improving liver function damage and application thereof
  • Composition for improving liver function damage and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] A composition, each component of the composition and the mass parts added are: 1 part of citrus flavonoids, 1 part of citrus fiber and 1 part of fructooligosaccharide.

Embodiment 2

[0042] A composition, each component of the composition and the mass parts added are: 100 parts of citrus flavonoids, 100 parts of citrus fiber and 100 parts of fructooligosaccharide.

Embodiment 3

[0044] A composition, each component of the composition and the added mass parts are: 50 parts of citrus flavonoids, 35 parts of citrus fiber and 60 parts of fructooligosaccharide.

[0045] Perform further effect detection on the above embodiments.

[0046] Fifty 6-week-old female C57BL / 6 mice with similar degrees of hepatitis fed with sucralose were divided into five groups (n = 10), and the animal experiments were carried out in the animal room of Wuhan Institute of Virology for 10 weeks. The feeding conditions were: SPF grade, 12h light-dark cycle, room temperature kept at 22±1°C, humidity 40-60%, grouping situation: a is the group of Example 1 (normal food and 50mg / mL of sterilization of the composition described in Example 1 aqueous solution), b blank control group (normal food and sterilized water), c is embodiment 2 group (sterilized aqueous solution of the composition described in normal food and 50mg / mL embodiment 2), d is the fructooligosaccharide group (normal food...

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PUM

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Abstract

The invention provides a composition for improving liver function damage and an application thereof. The composition comprises citrus flavonoid, citrus fibers and fructo-oligosaccharide. The combination of citrus flavonoid, citrus fibers and fructo-oligosaccharide in the composition has the effect of reducing the content of alanine aminotransferase (ALT) and alkaline phosphatase (ALP) in the liver, and can also reduce the content of inflammatory mediator factor bacterial lipopolysaccharide (LPS) and interleukin-6 (IL-6) in the liver, can relieve liver function damage caused by increasing of content of any one of ALT, ALP, LPS or IL-6, and is capable of treating or improving liver inflammation caused by long-term eating of artificial sweeteners such as sucralose or saccharin.

Description

technical field [0001] The invention relates to the technical field of health care products, in particular to a composition for improving liver function damage and its application. Background technique [0002] Artificial sweeteners mainly refer to some chemical substances that have a sweet taste but are not sugars. The sweetness is generally 10 times to hundreds of times higher than that of sucrose. Currently, they are widely used as sugar substitutes in cakes, beverages and other foods. However, eating too much artificial sweeteners, like sugar, will have a certain impact on your health, especially disrupting the body's glucose metabolism, causing liver inflammation, and damaging liver function. [0003] Citrus flavonoids are natural plant flavonoids. In recent years, studies have found that it has a variety of medicinal effects, including anti-oxidation, anti-tumor, anti-inflammatory, lipid-lowering, hypoglycemic, cardiovascular system, nervous system, and immune system. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/105A23L33/21A23L33/125A23L27/30A61K36/752A61P1/16A61K31/702
CPCA23L33/105A23L33/21A23L33/125A23L27/33A23L27/30A61K36/752A61K31/702A61P1/16A23V2002/00
Inventor 李慧灵周金林张利民石遵计卢宇靖林丽薇陈宏基邓诚
Owner MEIZHOU GOLDEN POMELO HEALTH TECH CO LTD
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