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Pharmaceutical preparation for improving immunity

A pharmaceutical preparation and immunity technology, applied in the field of medicine, can solve problems such as increased mortality, and achieve the effect of reducing the occurrence of diseases, reducing cardiovascular diseases, and increasing the number of diseases

Inactive Publication Date: 2020-08-21
张建波 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Compared with patients with good immune reconstitution, such patients are more likely to develop AIDS or develop non-AIDS related diseases, such as cardiovascular disease, liver and kidney disease, etc., resulting in increased mortality

Method used

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Examples

Experimental program
Comparison scheme
Effect test

experiment example

[0015] Among the patients receiving antiretroviral therapy (ART) for a long time in the hospital, 30 patients with poor immune reconstitution and abnormal fat metabolism such as hyperlipidemia due to taking ART were selected, and a pre-experimental observation was carried out, which was approved by the ethics committee approve.

[0016] A total of 30 people were enrolled and randomly divided into 3 groups, 10 people in each group, which were the treatment group (combined treatment group), the total ginsenosides treatment group (treatment group), and the observation group. Combined treatment group and treatment double-blind enrollment.

[0017] Inclusion criteria: Under the premise of ensuring good compliance, antiretroviral therapy (ART) has been received for more than 3 years, HIV-RNA cannot be detected, CD4+T lymphocytes do not increase, or the increase is less than 100 / ul, HIV-infected persons aged 18-60 with CD4+T lymphocytes below 350 / ul. Volunteer to participate in thi...

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PUM

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Abstract

The invention provides a medicinal preparation for improving immunity. The medicinal preparation comprises the following raw materials: ginsenoside Rg1 extracted from pseudo-ginseng monomers, whereinthe total ginsenoside Rg1 is ginsenoside. The pharmaceutical preparation provided by the invention has a treatment effect on people with poor immune reconstruction, and can increase the number of CD4+T lymphocytes. Therefore, the preparation can improve and regulate the immunity of a human body, reduce diseases, reduce hyperlipidemia and reduce cardiovascular diseases, can be used as an AIDSadjuvant drug, and can also be used for health care and disease prevention of common people as well as treatment and immunoregulation of people with hyperlipidemia.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a pharmaceutical preparation for improving immunity. Background technique [0002] Acquired immunodeficiency syndrome (AIDS, AIDS) is a serious infectious disease caused by human immunodeficiency virus (HIV). HIV is a retrovirus, and its reverse transcription process is the process of synthesizing proviral DNA with viral RNA as a template under the action of viral reverse transcriptase. Antiretroviral drugs are a class of drugs that treat retroviral (mainly HIV) infections. Although long-term antiretroviral therapy (ART) can effectively inhibit the replication of HIV-1, increase the number of CD4+ T lymphocytes in peripheral blood, and rebuild the immune function of patients, about 20% of HIV / AIDS patients still suffer from The number of CD4+ T lymphocytes cannot be restored to normal levels, and we call such patients poor immune reconstitution (immunological non-responder, IN...

Claims

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Application Information

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IPC IPC(8): A61K36/258A61K31/704A61P37/04A61P3/06A61P9/00A61P31/18
CPCA61K31/704A61K36/258A61P3/06A61P9/00A61P31/18A61P37/04A61K2300/00
Inventor 张建波徐克沂
Owner 张建波
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