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A sample holder for imaging a plurality of samples

A holder and sample technology, applied in the field of microscopy, can solve problems that hinder the use of microscopes

Inactive Publication Date: 2020-08-28
EURO LAB FUER MOLEKULARBIOLOGIE EMBL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This requires imaging of biological samples at regular intervals over hours or possibly days, which precludes the use of microscopes for imaging other samples

Method used

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  • A sample holder for imaging a plurality of samples
  • A sample holder for imaging a plurality of samples
  • A sample holder for imaging a plurality of samples

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Embodiment Construction

[0038] The present invention will now be described in detail. The figures and examples are provided for a better illustration of the invention. It will be understood that the embodiments and aspects of the invention described herein are examples only and do not limit the scope of protection in any way. The invention is defined by the claims and their equivalents. It will be appreciated that features of one aspect or embodiment of the invention may be combined with features of another or more aspects and / or embodiments of the invention.

[0039] figure 1 A portion of a light sheet microscope 100 according to the state of the art is shown. A non-limiting example of microscope 100 is in Figure 7 shown in summary. Microscope 100 has at least one illumination objective 20 and at least one detection objective 30 . exist figure 1 In the aspect of the microscope 100 shown in , two illumination objectives 20a, 20b and one detection objective 30 are shown. The illumination obje...

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Abstract

A sample holder comprises one or more elongated sample tubes. The one or more elongated sample tubes are adapted for accommodating a plurality of samples to be imaged at an imaging position. The imaging position is defined by at least one illumination objective lens and at least one detection objective lens of a microscope. A microscope is disclosed, comprising at least one illumination objectivelens and at least one detection objective lens, which define an imaging position. The microscope further comprises a sample holder for holding a plurality of samples. The sample holder is moveable with respect to the imaging position. A method for imaging a plurality of samples by means of the microscope is disclosed.

Description

technical field [0001] The present invention relates to sample holders for holding a plurality of samples to be imaged. The invention also relates to a microscope comprising a sample holder, at least one illumination objective and at least one detection objective. The invention also relates to a method for imaging a plurality of samples using a microscope comprising at least one illumination objective and at least one detection objective. Background technique [0002] Light sheet microscopy is an increasingly popular technique for imaging biological samples at high speed, with high three-dimensional resolution and using moderate light doses. A light sheet microscope has an illumination light path and a detection light path. The illumination light path and the detection light path are arranged substantially perpendicular to each other at the location of the biological sample. [0003] Light sheet microscopy is described, for example, in European patent EP 2 107 408 . In t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G02B21/00G01N21/64G02B21/16G02B21/36G01N21/13G02B21/26G02B21/34
CPCG02B21/0076G02B21/16G02B21/26G02B21/34G02B21/367G01N21/13G01N2021/135G01N21/01G02B21/06
Inventor H·福克L·胡夫纳格尔A·奥莱赫莱
Owner EURO LAB FUER MOLEKULARBIOLOGIE EMBL