Traditional Chinese medicine composition for treating ischemic stroke and application of traditional Chinese medicine composition

Abstract

The invention relates to the field of traditional Chinese medicine and pharmacy, in particular to a traditional Chinese medicine composition for treating ischemic stroke and an application of the traditional Chinese medicine composition. The traditional Chinese medicine composition consists of six medicines of raw milkvetch roots, dried rehamnnia roots, raw radix scutellariae, earthworms treated in wine, raw lobed ku-dzuvine roots, raw safflowers and the like. According to the traditional Chinese medicine composition, cerebral infarction volume can be reduced, neurological function damage canbe reduced, brain tissue MDA content can be reduced, and SOD activity is improved. The 6-keto-PGF1 alpha content is increased, and the TXB2 content is reduced. The traditional Chinese medicine composition has the effects of resisting free radical damage, resisting thrombosis and improving fibrinolytic activity, and effects of thrombolysis and dethrombosis. Compared with Naoxintong and other contrast inventions, the traditional Chinese medicine composition has notable protection effects on cerebral ischemia reperfusion damage; and compared with different dosage compounding ratios, the formula of the traditional Chinese medicine composition is more scientific. The experiment provides a reference for a mechanism for protecting cerebral ischemia reperfusion damage, and experiment data is provided for clinical application of the traditional Chinese medicine composition in the respect of cerebral vessels.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating ischemic stroke and its application. Background technique [0002] Ischemic stroke (called ischemic stroke in traditional Chinese medicine) seriously endangers human life and quality of life. The top three, the high disability rate and recurrence rate bring a heavy burden to the society. Ischemic stroke accounts for about 50% to 65% of cerebrovascular diseases, and this disease has become an important topic of concern to the medical circles at home and abroad. [0003] At present, Chinese patent medicines for the treatment of ischemic stroke are mostly based on Qi deficiency and blood stasis, and they are treated with Qi-invigorating and blood-activating drugs or medicines for promoting blood circulation. An et al.), although there are curative effects, but most of them are "replenishing qi and activating blood"...

AI Technical Summary

Problems solved by technology

[0003] At present, Chinese patent medicines for the treatment of ischemic stroke are mostly based on qi deficiency and blood stasis, and are treated with nourishing qi and activating blood or blood activating medicines, such as Buyang Huanwu Decoction (such as Naoxintong Capsules, Naofukang, Tongxinluo Capsules, Naoluo An et al.), although there are curative effects, but most of them are "replenishing qi and activating blood", which can easily cause injury to yin and reduce dryness, aggravate heat stasis, cerebral hemorrhage, cerebral ischemia-reperfusion injury and other disadvantages, and the curative effect needs to be improved.

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