35results about How to "Has antithrombotic effect" patented technology

The invention discloses a method for producing nanometer functional sugar. The method comprises the following steps of crushing and processing raw materials in a crushing tube for 60 to 180 minutes; meanwhile, controlling the rotating speed of a stirring rod to be 2000 to 6000 r/min; in addition, controlling the ultrasonic frequency to be about 30k to 90 k Hz; finally, performing refining for 30 to 120 minutes in an airflow crushing machine; finally, obtaining the nanometer functional sugar with the particle diameter being 20 to 40 nm; controlling the molecular weight distribution of the nanometer functional sugar within 10,000 to 20,000 Da. When the nanometer functional sugar is applied to a hyperglycemic product, after the eating, the blood sugar can be obviously reduced; in the dosage range of 0.5g/kg to 2.0g/kg, the hyperglycemic effect is improved along with the dosage; in addition, the nanometer functional sugar is subjected to sulfuric acid esterification modification; the sulfuric acid esterification derivatives with good water solubility are obtained; the sulfuric acid esterification derivatives have the anticoagulation and antithrombus effects.

The invention relates to a Chinese medicine composition prescription for treating cardiovascular and cerebrovascular diseases and preparation process, wherein the Chinese medicinal composition comprises raw materials and auxiliary material, the raw materials include seabuckthorn fruit extract 1-6 parts, rhizome of Sichuan lovage 1-6 parts, root of red rooted saliva 1-6 parts, banksia rose 1-6 parts, red peony root 1-6 parts, safflower 1-6 parts, haw 1-6 parts, and flatsedge tuber 1-6 parts.

The invention discloses a Chinese chestnut beer and a preparation method thereof. The Chinese chestnut beer is prepared by blending the following raw materials in parts by weight: 100 parts of water, 0.5 parts of maltose, 5 parts of Chinese chestnut syrup, 8 parts of panaxoside, 1 part of rice soup, 6 parts of Chinese-date juice, 4 parts of Chinese chestnut alcohol and 0.15 part of hop. Compared with the Chinese chestnut beer in the present market, the Chinese chestnut beer disclosed by the invention is aromatic, tasty and refreshing, and has the sweet of the Chinese chestnut and the Chinese date; as the raw materials preparing the Chinese chestnut beer are rich in higher medicine nutritional values, after being drank, the Chinese chestnut beer can build the bodies, lengthen the life, improve the immunity of human bodies, regulate the blood pressure and the blood fat of human bodies, effectively improve the memory, and is suitable for both children and adults.

The invention belongs to the biotechnology field and particularly relates to a chimeric monoclonal antibody which is capable of being combined with high specificity and high affinity of platelet membrane glycoprotein and has an antithrombotic bioactivity and applications of the chimeric monoclonal antibody. The human-mouse chimeric monoclonal antibody against human platelet membrane glycoprotein Ib alpha is characterized by comprising a mouse heavy chain variable region and a mouse light chain variable region, wherein amino acid sequence of the mouse heavy chain variable region is represented as SEQ ID No.1, and amino acid sequence of the mouse light chain variable region is represented as SEQ ID No.2. Immune reactivity of antibody molecules is mainly produced by a constant region, so that the chimeric antibody containing a human constant region is not easy to generate an anti-mouse immune reaction in human bodies. The monoclonal antibody against platelet glycoprotein (GP) Ib alpha is capable of being combined with high specificity and high affinity of human and rhesus monkey platelet membrane glycoprotein Ib alpha (GP Ib alpha), and the antithrombotic effect is achieved.

A Chinese medicine in the form of mixture, dripping pill, particle, oral liquid, tablet, capsule, or injection for preventing and treating ischemic cerebrovascular diseases such as cerebral arteriosclerosis, hpyomnesia, dizziness, cerebral ischemia, cerebral infarction, etc is prepared from seabuckthorn fruit, ginkgo leaf, tea leaf and auxiliary through extracting.

The invention provides a Chinese medicinal preparation for preventing and treating senile dementia which is prepared from the following raw material herbs (by weight portion): prepared rehmannia root 10-50 parts, fleece-flower root 15-55 parts, hairy deer horn 8-36 parts, kudzuvine root 3-20 parts, ginkgo leaves powder 13-40 parts, acorus gramineus soland 5-30 parts, and Chinese angelica root 5-30 parts.

The invention provides a traditional Chinese medicine composition for treating tachyarrhythmia and a preparation method and application thereof. The traditional Chinese medicine composition for treating tachyarrhythmia is prepared from, by weight, 20-40 parts of radix sophorae flavescentis, 6-30 parts of honey-fried licorice roots, 12-15 parts of poria with hostwood, 10-15 parts of American ginseng, 20-30 parts of radix ophiopogonis, 15-40 parts of colla corii asini, 12-15 parts of radix angelica sinensis and 15-30 parts of radix rehmanniae recen. The traditional Chinese medicine composition is mainly used for tonifying the heart and calming the heart and nerves, is supplemented by tonifying liver blood and kidney essence and removing stasis for promoting tissue regeneration, has the effects of slowing down the heart rhythm, inhibiting the cardiac ectopic pacing point and the like, has the effects of enhancing the cardiac contraction function, increasing the coronary blood flow, improving myocardial ischemia, adjusting blood fat, adjusting blood sugar and the like, can treat tachyarrhythmia and has a good adjusting effect on common coronary heart diseases, diabetes, dyslipidemia and other complications.

Traditional Chinese medicine comprising radix paeoniae rubra comprises the following components in parts by mass: 50-100 parts of radix paeoniae rubra, 40-70 parts of angelica, 10-20 parts of liquorice, 20-30 parts of szechuan lovage rhizome, 30-40 parts of angelica dahurica, 25-35 parts of radix salviae miltiorrhizae, 15-25 parts of tuckahoe, 60-80 parts of cane sugar and 5-7 parts of magnesium stearate; as the radix paeoniae rubra, the angelica, the liquorice and the like are used as raw materials, the traditional Chinese medicine is free of hormone and antibiotic ingredients in foreign medicine, and can not produce drug resistance; with the adoption of natural vegetation, studies have found that the traditional Chinese medicine has no obvious toxic side effects, and is high in safety, easy to absorb, fast in onset, and convenient to use; a finished product of the traditional Chinese medicine containing radix paeoniae rubra has effects of preventing the formation of thrombus, preventing aggregation of blood plates, reducing blood fat and preventing arteriosclerosis, has no side effects on a cardiovascular system, can protect a liver, can treat dysmenorrheal, can promote blood circulation to remove blood stasis, is low in cost and simple in process, and can be widely used.

The invention provides a natto kinase composition having antithrombus effect, a preparation method, and an application thereof in healthcare foods having thrombus prevention effect. The natto kinase composition is prepared from: natto kinase, maltodextrin, a spice and a corrective agent. The natto kinase composition has antithrombus effect, is safe and is free of toxic and side effects, has good stability, has functions of preventing thrombogenesis, dissolving the thrombus, reducing blood viscosity and improving blood circulation, and softening blood vessels and increasing elasticity thereof,and is suitable for various healthcare foods.

The invention relates to the field of traditional Chinese medicine and pharmacy, in particular to a traditional Chinese medicine composition for treating ischemic stroke and an application of the traditional Chinese medicine composition. The traditional Chinese medicine composition consists of six medicines of raw milkvetch roots, dried rehamnnia roots, raw radix scutellariae, earthworms treated in wine, raw lobed ku-dzuvine roots, raw safflowers and the like. According to the traditional Chinese medicine composition, cerebral infarction volume can be reduced, neurological function damage canbe reduced, brain tissue MDA content can be reduced, and SOD activity is improved. The 6-keto-PGF1 alpha content is increased, and the TXB2 content is reduced. The traditional Chinese medicine composition has the effects of resisting free radical damage, resisting thrombosis and improving fibrinolytic activity, and effects of thrombolysis and dethrombosis. Compared with Naoxintong and other contrast inventions, the traditional Chinese medicine composition has notable protection effects on cerebral ischemia reperfusion damage; and compared with different dosage compounding ratios, the formula of the traditional Chinese medicine composition is more scientific. The experiment provides a reference for a mechanism for protecting cerebral ischemia reperfusion damage, and experiment data is provided for clinical application of the traditional Chinese medicine composition in the respect of cerebral vessels.

The invention discloses mushroom composite powder. The powder is prepared from the following raw materials in parts by weight of 15-25 parts of russula vinosa, 10-30 parts of gloeostereum incarnatum, 15-30 parts of bolete, 15-30 parts of black fungus and 15-30 parts of lentinula edodes. The preparation method comprises the following steps of S1, weighing the following raw materials of 15-25 parts of russula vinosa, 10-30 parts of gloeostereum incarnatum, 15-30 parts of bolete, 15-30 parts of black fungus and 15-30 parts of lentinus edodes; S2, performing dehydrating and drying: sorting and cleaning the raw materials, and then performing dehydrating and drying; S3, performing crushing: crushing the dehydrated raw materials into powder; and S5, performing mixing and packaging: mixing the raw material powder, and performing packaging. The mushroom powder disclosed by the invention realizes the effect complementation of active ingredients, has a comprehensive health-care effect on the human body, and regulates the functions of the human body.

The invention discloses morchella composite powder. The powder is prepared from the following raw materials in parts by weight of 15-25 parts of morchella, 10-30 parts of tricholoma matsutake, 15-25 parts of lycoperdon spp., 15-25 parts of inonotus obliquus and 15-30 parts of phellinus igniarius. The preparation method comprises the following steps of S1, weighing the following raw materials in parts by weight of 15-25 parts of morchella, 10-30 parts of tricholoma matsutake, 15-25 parts of lycoperdon spp., 15-25 parts of inonotus obliquus and 15-30 parts of phellinus igniarius; S2, performing dehydrating and drying: sorting and cleaning the raw materials, and then performing dehydrating and drying; S3, performing crushing: crushing the dehydrated raw materials into powder; and S5, performing mixing and packaging: mixing the raw material powder, and performing packaging. The morchella powder disclosed by the invention realizes the effect complementation of active ingredients, has a comprehensive health-care effect on the human body, and regulates the functions of the human body.

The invention discloses stiff silkworm protein polypeptide wine and a preparation method thereof. The stiff silkworm protein polypeptide wine is prepared from the following components in parts by weight: 0.5-1.8 parts of stiff silkworm protein polypeptide, 5-8 parts of scorpion, 5-8 parts of periostracum cicade, 4-6 parts of ligusticum wallichii, 4-6 parts of gastrodia elata, 4-6 parts of garden balsam stem, 4-6 parts of earthworms and 75-85 parts of yellow wine with the alcohol concentration of 10-15%. According to the invention, the stiff silkworm protein polypeptide is taken as a main ingredient, traditional Chinese medicine auxiliary materials such as scorpion, periostracum cicade, ligusticum wallichii, gastrodia elata, garden balsam stem and earthworms are combined, and health medicinal liquor which can prolong thrombin time, can inhibit a thrombin-fibrinogen reactant and also has anticoagulation and antithrombotic effects is prepared, when the stiff silkworm protein polypeptide wine and the health wine are used cooperatively, synergistic effect can be realized, the anticoagulation and antithrombotic effects are achieved, the stiff silkworm protein polypeptide wine is applicable to middle aged people and elderly people as a daily health care product and is strong in practicability, safe and reliable.