Taurine and medical combination for treating cardiovascular and cerebrovascular diseases

A technology for cardiovascular and cerebrovascular diseases and compositions, applied in the field of medicine, to prolong the time of carotid artery thrombosis, improve cerebral circulation, and reduce cerebral ischemia-reperfusion injury

Inactive Publication Date: 2010-11-17
JIANGYIN TIANJIANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0016] At present, using one or more interactions between taurine and tanshinone IIA or its pharmaceutically acceptable salt, Panax notoginseng saponins, safflower yellow, total flavonoids of hawthorn leaves, puerarin, and breviscapine, the compatibility group Recipe, used for the preparation of medicines for the treatment of cardiovascular and cerebrovascular diseases, has not been reported yet

Method used

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  • Taurine and medical combination for treating cardiovascular and cerebrovascular diseases
  • Taurine and medical combination for treating cardiovascular and cerebrovascular diseases
  • Taurine and medical combination for treating cardiovascular and cerebrovascular diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0193] Embodiment 1 Preparation of the pharmaceutical composition aqueous injection of the present invention

[0194] prescription:

[0195] Prescription 1: Niudan Injection

[0196] Taurine 3kg

[0197] Sodium Tanshinone IIA Sulfonate 10g

[0198] Polysorbate 80 40g

[0199] PEG400 300ml

[0200] Add water for injection to 10000ml

[0201] A total of 1000 sticks were prepared

[0202] Prescription 2: Niusan Injection

[0203] Taurine 3kg

[0204] Panax notoginseng saponins 100g

[0205] Polysorbate 80 40g

[0206] PEG400 300ml

[0207] Add water for injection to 10000ml

[0208] A total of 1000 sticks were prepared

[0209] Prescription 3: Niuhong Injection

[0210] Taurine 3kg

[0211] Safflower Yellow 50g

[0212] Polysorbate 80 40g

[0213] PEG400 200ml

[0214] Add water for injection to 10000ml

[0215]A total of 1000 sticks were prepared

[0216] Prescription 4: Niushan Injection

[0217] Taurine 3kg

[0218] Hawthorn Leaf Total Flavonoids 50g

...

Embodiment 2

[0249] Embodiment 2 Preparation of the powder injection of the pharmaceutical composition of the present invention

[0250] prescription:

[0251] Prescription 1: Niudan for injection

[0252] Taurine 3kg

[0253] Sodium Tanshinone IIA Sulfonate 10g

[0254] Polysorbate 80 40g

[0255] PEG400 300ml

[0256] Mannitol 800g

[0257] Add water for injection to 10000ml

[0258] A total of 1000 sticks were prepared

[0259] Prescription 2: Niusan for injection

[0260] Taurine 3kg

[0261] Panax notoginseng saponins 100g

[0262] Polysorbate 80 50g

[0263] PEG400 400ml

[0264] Mannitol 800g

[0265] Add water for injection to 10000ml

[0266] A total of 1000 sticks were prepared

[0267] Prescription 3: Bull Red for Injection

[0268] Taurine 3kg

[0269] Safflower Yellow 50g

[0270] Polysorbate 80 30g

[0271] PEG400 200ml

[0272] Mannitol 800g

[0273] Add water for injection to 10000ml

[0274] A total of 1000 sticks were prepared

[0275] Prescription...

Embodiment 3

[0310] Embodiment 3 Preparation of the pharmaceutical composition sodium chloride infusion of the present invention

[0311] prescription:

[0312] Prescription 1: Niudan Sodium Chloride Injection

[0313] Taurine 3kg

[0314] Sodium Tanshinone IIA Sulfonate 10g

[0315] Polysorbate 80 50g

[0316] PEG400 400ml

[0317] Sodium chloride 4500g

[0318] Add water for injection to 500000ml

[0319] A total of 1000 bottles were prepared

[0320] Prescription 2: Bovine Sodium Trichloride Injection

[0321] Taurine 3kg

[0322] Panax notoginseng saponins 100g

[0323] Polysorbate 80 50g

[0324] PEG400 400ml

[0325] Sodium chloride 4500g

[0326] Add water for injection to 500000ml

[0327] A total of 1000 bottles were prepared

[0328] Prescription 3: Niuhong Sodium Chloride Injection

[0329] Taurine 3kg

[0330] Safflower Yellow 50g

[0331] Polysorbate 80 50g

[0332] PEG400 400ml

[0333] Sodium chloride 4500g

[0334] Add water for injection to 500000ml ...

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PUM

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Abstract

The invention discloses a medical component with taurine and medicine to treat blood vessel of brain and heart disease, preparing method and usage in medical technical domain, which is characterized by the following: choosing the blood vessel of brain and heart disease medicine from one or several tanshinone IIA, medical salt, Notoginsen triterpenes, carthamus tinctorius yellow colour, haw leaf total flavone, puerarin and lamp-dish flower element; choosing tanshinone IIA or medical salt as tanshinone IIA mahogany. This invention can used to treat coronary disease, angina pectoris and so on.

Description

【Technical field】 [0001] The invention relates to a pharmaceutical composition mainly made of taurine and at least one drug for treating cardiovascular and cerebrovascular diseases, a preparation method and application thereof, and belongs to the technical field of medicine. 【Background technique】 [0002] In recent years, with the improvement of living standards, accelerated pace of life, and increased work pressure, the incidence of various cardiovascular and cerebrovascular diseases, such as stroke, cerebrovascular insufficiency, hypertension, angina pectoris, myocardial infarction, and sudden death, is increasing day by day, and the age of onset is ahead of the trend. According to incomplete statistics, more than half of the individuals who are engaged in mental work around the age of 40 are in a sub-healthy state, a quarter of the individuals have symptoms of cardiovascular and cerebrovascular diseases in their early years, and about 10% suffer from relatively serious c...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/255A61K31/343A61K31/704A61K31/7048A61K9/02A61K9/08A61P9/10A61P9/12
Inventor 黄振华
Owner JIANGYIN TIANJIANG PHARMA
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