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Toothpaste capable of inhibiting Helicobacter pylori, and preparation method of toothpaste

A technology of Helicobacter pylori and toothpaste is applied in the field of toothpaste that can inhibit Helicobacter pylori and its preparation, and can solve the problems of difficult removal, stubborn bad breath and the like, and achieve the effect of improving bad breath.

Pending Publication Date: 2020-10-13
福州幽力克生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After being infected with Helicobacter pylori, Helicobacter pylori can cause gastritis, periodontitis, etc., thereby causing bad breath, and bad breath is very stubborn and difficult to remove

Method used

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  • Toothpaste capable of inhibiting Helicobacter pylori, and preparation method of toothpaste
  • Toothpaste capable of inhibiting Helicobacter pylori, and preparation method of toothpaste
  • Toothpaste capable of inhibiting Helicobacter pylori, and preparation method of toothpaste

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] A kind of preparation method that can suppress the toothpaste of helicobacter pylori, described concrete steps are as follows:

[0050] S1. Take out the components of component B in sequence, and ultrasonically stir for 1-1.5 hours to make it evenly stirred;

[0051] S2. Take out the components of component A one by one, then ultrasonically stir for 0.5-1h, then pour the stirred mixture into the mixer of S1 to mix and stir evenly, and emulsify;

[0052] S3. Add component C to the mixer of S2 and continue stirring for 1-1.5h

[0053] S4. Pour component D into the mixer of S3 and stir for 0.5-1h; if there is no component D, this step is omitted;

[0054] S5. Perform homogenization and stand still for 4-8 hours to obtain toothpaste.

[0055] Prepare different toothpaste respectively according to table 1 according to preparation method of the present invention:

[0056]

[0057]

[0058] Table 1

[0059] Put each toothpaste into the toothpaste tube after it is mad...

Embodiment 2

[0061] Select 100 cases of Helicobacter pylori-positive patients with bad breath (the mouth has peculiar smell or bad smell), and 100 cases of non-Helicobacter pylori-positive patients with bad breath, and divide them into five groups, with 20 cases of Helicobacter pylori-positive patients and 20 cases of non-Helicobacter pylori-positive patients in each group. Bacteria-positive patients with bad breath were named as experimental group 1, experimental group 2, experimental group 3, experimental group 4, and control group, and experimental group 1, experimental group 2, experimental group 3, experimental group 4, and control group were used and implemented The No. 1 toothpaste, No. 2 toothpaste, No. 3 toothpaste, No. 4 toothpaste, and the toothpaste of the control group in Example 1, each time in the morning and evening, each time about 1 cm (about 1g), brush your teeth with an ordinary soft-bristled toothbrush, and brush your teeth for at least 1 g each time. 5 minutes, the tes...

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Abstract

The invention discloses a toothpaste capable of inhibiting Helicobacter pylori, and a preparation method of the toothpaste. The toothpaste is composed of the following raw materials in parts by weight: 27-36.5 parts of a component A, 57-82 parts of a component B, and 0.35-1.3 parts of a component C, wherein the component A comprises 25-30 parts of hydrated silica, 1-2.5 parts of glycerin laurate,and 1-4 parts of cellulose gum; the component B comprises 40-55 parts of sorbitol, 0.1-0.4 part of IgY, 0.04-0.06 part of sodium pyrophosphate, 1-2 parts of cocamidopropyl betaine, and 10-15 parts ofwater; and the component C comprises 0.04-0.07 part of amstat, and 0.1-0.4 part of nisin. The IgY component used in the toothpaste can effectively inhibit Helicobacter pylori in the oral cavity, and thereby the problem of bad breath is alleviated and improved. The toothpaste also uses a variety of food-grade antibacterial and antiviral components, microorganisms that cause the rot of food residuesin the oral cavity and cause tooth damages and oral inflammations can be simultaneously inhibited, and thereby the oral problems are improved.

Description

technical field [0001] The invention relates to daily chemical products, in particular to a toothpaste, in particular to a toothpaste capable of inhibiting Helicobacter pylori and a preparation method thereof. Background technique [0002] Helicobacter pylori is a helical, slightly anaerobic bacteria that requires very harsh growth conditions. Helicobacter pylori can be divided into oral Helicobacter pylori and gastric Helicobacter pylori. This bacterial infection first causes oral ulcers, chronic gastritis , and lead to gastric ulcer and gastric atrophy, severe cases will develop into gastric cancer, and there is a parallel relationship between Helicobacter pylori infection and gastric cancer mortality; [0003] However, the existing methods of inhibiting Helicobacter pylori are only to suppress and kill them by taking drugs when symptoms appear. However, most of these anti-inflammatory ingredients are medicinal ingredients, and many of them are chemically synthesized raw m...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/73A61K8/64A61K8/44A61K8/37A61K8/24A61K8/25A61K8/34A61K8/66A61P1/02A61P31/04A61Q11/00
CPCA61K8/9789A61K8/64A61K8/731A61K8/44A61K8/442A61K8/375A61K8/345A61K8/66A61K8/25A61K8/24A61Q11/00A61P1/02A61P31/04
Inventor 陈颖
Owner 福州幽力克生物科技有限公司
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