The invention relates to the technical field of health-care foods, in particular to a composition for invigorating the spleen and nourishing the stomach, food therapy granules containing the composition and a preparation method of the composition. The composition comprises the following raw material components: red beans, oat, black sesame seeds, brown rice, red jujubes, carrots, corn, wheat germs, millet, lotus roots, Chinese yams, soybeans, poria cocos, haws, Chinese chestnuts, apples, brown sugar powder and whole milk powder. According to the composition for invigorating the spleen and nourishing the stomach, the food therapy granules containing the composition and the preparation method of the composition, provided by the invention, any food additives are not added, the composition and the food therapy granules are balanced in nutrients, aromatic in taste, and convenient to eat. The formula is novel and scientific, the components are reasonable in compounding ratio, and the composition and the food therapy granules are free from toxic and side effects, are simple in preparation method, and mature in technology, are adapted to wide ranges of crowds, are good in eating effect, have remarkable efficacy of invigorating the spleen, nourishing the stomach, invigorating the stomach, promoting digestion and the like, and are suitable for sub-health crowds with deficiency of the spleen and the stomach and low gastrointestinal motility to eat for a long term.