A natto polypeptide soybean milk powder instant food is characterized by being prepared from 12 nutrient substances including nattokinase extracts, soybean polypeptide extracts, ginseng polypeptide extracts, bitter melon polypeptide extracts, lecithin powder, white kidney bean powder, chickpea powder, black soybean milk powder, skim milk powder, glucomannan powder, xylooligosaccharide and inulin.The raw materials are weighed, matched, dried, sterilized, packaged, boxed and the like to prepare the natto polypeptide soybean milk powder instant food. The instant food is scientific in formula andcomprehensive in function and has various health effects of protecting heart and cerebral vessels, preventing the cerebral thrombosis, atherosclerosis and alzheimer's disease, improving the fatty liver, improving the liver functions, regulating intestinal flora, relaxing bowels, reducing blood lipid, blood glucose and blood pressure, eliminating cholesterol, delaying senescence and the like.