Application of traditional Chinese medicine composition in preparation of medicine for treating viral pneumonia

A technology for viral pneumonia and a composition is applied in the application field of traditional Chinese medicine compositions in the preparation of medicines for the treatment of viral pneumonia, and can solve the problems of restricting the clinical use of medicines, toxic and side effects, and the like

Inactive Publication Date: 2020-10-23
武汉贝参药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because the current influenza virus is resistant to amantadine drugs, WHO and the US CDC recommend neuraminidase inhibitors as the first-line treatment of influenza antiviral drugs. clinical use

Method used

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  • Application of traditional Chinese medicine composition in preparation of medicine for treating viral pneumonia
  • Application of traditional Chinese medicine composition in preparation of medicine for treating viral pneumonia
  • Application of traditional Chinese medicine composition in preparation of medicine for treating viral pneumonia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] This embodiment provides a traditional Chinese medicine composition, which includes the following raw materials in parts by weight: 33 parts of Radix Pseudostellariae, 17 parts of Fritillaria chinensis, 17 parts of Trichosanthes trichosanthes, 10 parts of Baiji, 8 parts of licorice, and 10 parts of betel nut According to the following preparation method, a Chinese medicine composition is prepared: take said Radix Pseudostellariae, Fritillaria chinensis, Trichosanthum Fensis, Radix Radix Radix Glycyrrhizae, Radix Glycyrrhizae and betel nut and grind them respectively, and then mix them uniformly to obtain said Chinese medicine composition

Embodiment 2

[0025] The difference between this example and Example 1 is that the traditional Chinese medicine composition includes the following raw materials in parts by weight: 30 parts of Radix Pseudostellariae, 15 parts of Fritillaria japonicus, 15 parts of Trichosanthes trichosanthes, 5 parts of Baiji, 5 parts of licorice, and betel nut 5 servings.

Embodiment 3

[0027] The difference between this example and Example 1 is that the traditional Chinese medicine composition includes the following raw materials in parts by weight: 40 parts of Radix Pseudostellariae, 20 parts of Fritillaria japonicus, 20 parts of Trichosanthes trichosanthes, 15 parts of Baiji, 10 parts of Radix Glycyrrhizae, betel nut 15 servings.

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Abstract

The invention discloses an application of a traditional Chinese medicine composition in preparation of a medicine for treating viral pneumonia. The traditional Chinese medicine composition is preparedfrom the following raw materials in parts by weight: 30 to 40 parts of radix pseudostellariae, 15 to 20 parts of thunberg fritillary bulb, 15 to 20 parts of radix trichosanthis, 5 to 15 parts of rhizoma bletillae, 5 to 10 parts of liquorice root and 5 to 15 parts of betel nut. The viral pneumonia is pneumonia caused by any one of an influenza A virus H1N1, an influenza A virus H2N2, an influenzaB virus and a novel coronavirus. The traditional Chinese medicine composition disclosed by the invention can obviously inhibit the activity of viruses in mice infected by the viral pneumonia; the lungindex inhibition rate is higher than 20%; and meanwhile, the traditional Chinese medicine composition can also be used for adjusting the Th1 / Th2 cell proportion in a viral pneumonia infected mouse body, and adjusting the protein expression quantity of inflammatory response related factors IL-4, IL-5, IgE and IFN-gamma and the content of oxidative stress related substances GSH, T-AOC, MDA and SOD.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to the application of a traditional Chinese medicine composition in the preparation of medicines for treating viral pneumonia. Background technique [0002] Patent CN106361992A discloses a traditional Chinese medicine composition of Radix Pseudostellariae for relieving cough and benefiting qi and its traditional Chinese medicine preparation. In the traditional Chinese medicine composition, Radix Pseudostellariae is the monarch drug, Fritillaria japonicus and Trichosanthes trichosanthes are giant drugs and assist each other, and white root is an adjuvant drug, and licorice flavor As medicine, the traditional Chinese medicine composition has the effects of nourishing qi and nourishing yin, clearing the lung and resolving phlegm, nourishing the kidney and strengthening the spleen, relieving cough and relieving asthma, and mainly treating deficiency of b...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61P11/00A61P31/16A61P31/14
CPCA61K36/36A61K36/8966A61K36/428A61K36/898A61K36/484A61K36/889A61P11/00A61P31/16A61P31/14A61K2300/00
Inventor 董枭卢军熊齐春
Owner 武汉贝参药业股份有限公司
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