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A kind of tea oil composition for lowering fat and losing weight and its application, soft capsule and its preparation method

A lipid-lowering weight loss and composition technology, applied in the field of medicine, can solve the problems of high purity requirements, complex preparation process and low lipid-lowering activity of seabuckthorn seed extract, and achieve the effects of stable activity, improved process, and increased lipid-lowering efficacy.

Active Publication Date: 2022-04-29
SOUTH CHINA AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, the Chinese patent with publication number CN102266429A discloses a mixture of seabuckthorn seed extract and camellia oil, which has certain lipid-lowering activity, but has a single component and low lipid-lowering activity, and has high requirements for the purity of seabuckthorn seed extract. , the preparation process is complex

Method used

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  • A kind of tea oil composition for lowering fat and losing weight and its application, soft capsule and its preparation method
  • A kind of tea oil composition for lowering fat and losing weight and its application, soft capsule and its preparation method
  • A kind of tea oil composition for lowering fat and losing weight and its application, soft capsule and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-9

[0040] Embodiment 1-9 lipid-lowering and weight-reducing composition

[0041] This example provides a series of lipid-lowering and weight-reducing compositions, which are formed by mixing the components in parts by weight shown in Table 1.

[0042] Wherein, the prebiotic in each embodiment is fructooligosaccharide.

[0043] Table 1

[0044]

[0045] Wherein, the vegetable oil formula of each embodiment is as shown in table 2:

[0046] Table 2

[0047]

[0048] Wherein, the probiotic composition of each embodiment is as shown in table 3:

[0049] table 3

[0050]

[0051]

[0052] Among them, the live bacteria content of each probiotic is ≥10 10 cfu / g.

Embodiment 10

[0053] Example 10 Lipid-lowering activity test of various lipid-lowering and weight-reducing compositions

[0054] 1. Experimental method

[0055] The lipid-lowering and weight-reducing compositions prepared in Examples 1-9 were used as samples of the experimental group.

[0056] Take 110 170±20g healthy adult male SD rats and adapt to feeding for 1 week, then cut off the tip of the tail to take the tail vein blood, separate the serum, and use the kit to measure TC, TG, HDL-C, LDL-C as the basic value.

[0057] Divide into two groups randomly subsequently, blank group 10 are fed with commercially available basal feed; 100 high-fat groups are fed with commercially available high-fat feed; and 9 experimental groups, 9 experimental groups were fed with high-fat feed continuously (300mg / d / only), and the rest of the groups were fed with the same amount of distilled water, and were fed once a day at regular intervals. After 4 weeks of intervention, the tip of the tail was cut Take...

Embodiment 11-14

[0074] Example 11-14 Lipid-lowering and weight-loss soft capsules

[0075] 1. This embodiment provides a series of fat-lowering and slimming soft capsules, the composition of which is shown in Table 7.

[0076] Table 7

[0077]

[0078] 2. The preparation process of soft capsules is as follows: figure 1 shown

[0079] S1. Mixing of soft capsule contents: Weigh tea oil, vegetable oil, beeswax, vitamin E, prebiotics and probiotic freeze-dried powder according to the formula, and mix them evenly with a mixer. The mixing time is 20min, and the temperature of the mixer is 25 ℃, ambient humidity 40%;

[0080] S2. Preparation of capsule material liquid: put glycerin, gelatin, and distilled water into a colloidal sol tank according to the formula, stir and dissolve at 60°C, vacuum degas, and filter through a 100-mesh sieve to obtain the capsule material liquid;

[0081] S3. The content obtained in S1 and the capsule material liquid obtained in S2 are prepared into capsules thro...

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Abstract

The invention discloses a fat-reducing and weight-reducing tea oil composition and its application, a soft capsule and a preparation method thereof. oil, compound vegetable oil, prebiotics and probiotics, by adding compound vegetable oil to camellia oil, the composition ratio of fatty acids is effectively improved, and the lipid-lowering effect is improved, and the lipid-lowering effect is greatly improved by adding probiotics and prebiotics. And further developed a kind of soft capsule containing the composition, the soft capsule of the present invention contains vegetable oil and probiotic prebiotics, its lipid-lowering effect is greatly increased, and the source of rich raw materials is wide and easy to get at the same time, by improving the process, the probiotics The activity is more stable, the shelf life of the product is extended, and the obtained fat-reducing and weight-loss soft capsules are safe and have no side effects, and can be taken for a long time to prevent the occurrence of obesity.

Description

technical field [0001] The invention relates to the technical field of medicines, in particular to a lipid-lowering and weight-reducing tea oil composition and its application, a soft capsule and a preparation method thereof. Background technique [0002] Since 1975, the number of obese people in the world has nearly tripled. According to the World Health Organization, in 2016, more than 1.9 billion adults were overweight, of which more than 650 million were obese. At present, the prevalence of obesity in the Chinese population is also increasing year by year. From 2004 to 2014, the adult obesity rate increased from 3.3% to 14.0%, and the number of obese people has surpassed that of the United States. And a series of health problems caused by obesity seriously affect people's life. For example, obesity is a major risk factor for noncommunicable diseases, including cardiovascular disease, diabetes, musculoskeletal disorders, and certain cancers; moreover, the risk of develop...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/73A61P3/04A61P3/06A61K9/48A61K47/44A61K47/22A61K31/702A61K35/744A61K35/745A61K35/747A61K36/185A61K36/42A61K36/55A61K36/605
CPCA61K36/42A61K36/55A61K36/73A61K36/185A61K36/605A61K31/702A61K35/745A61K35/747A61K35/744A61K9/4858A61P3/06A61P3/04A61K2300/00
Inventor 吴雪辉肖希贤
Owner SOUTH CHINA AGRI UNIV
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