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Lipid-lowering and weight-reducing tea oil composition and application thereof, soft capsule and preparation method thereof

A lipid-lowering weight loss and composition technology, which is applied in the field of medicine, can solve the problems of high purity requirements, complex preparation process and low lipid-lowering activity of seabuckthorn seed extract, so as to improve and protect the function of blood vessel walls, reduce deposition, and reduce lipids. The effect of power gain

Active Publication Date: 2020-11-06
SOUTH CHINA AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

For example, the Chinese patent with publication number CN102266429A discloses a mixture of seabuckthorn seed extract and camellia oil, which has certain lipid-lowering activity, but has a single component and low lipid-lowering activity, and has high requirements for the purity of seabuckthorn seed extract. , the preparation process is complex

Method used

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  • Lipid-lowering and weight-reducing tea oil composition and application thereof, soft capsule and preparation method thereof
  • Lipid-lowering and weight-reducing tea oil composition and application thereof, soft capsule and preparation method thereof
  • Lipid-lowering and weight-reducing tea oil composition and application thereof, soft capsule and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-9

[0040] Embodiment 1-9 lipid-lowering and weight-reducing composition

[0041] This example provides a series of lipid-lowering and weight-reducing compositions, which are formed by mixing the components in parts by weight shown in Table 1.

[0042] Wherein, the prebiotic in each embodiment is fructooligosaccharide.

[0043] Table 1

[0044]

[0045] Wherein, the vegetable oil formula of each embodiment is as shown in table 2:

[0046] Table 2

[0047]

[0048] Wherein, the probiotic composition of each embodiment is as shown in table 3:

[0049] table 3

[0050]

[0051]

[0052] Among them, the live bacteria content of each probiotic is ≥10 10 cfu / g.

Embodiment 10

[0053] Example 10 Lipid-lowering activity test of various lipid-lowering and weight-reducing compositions

[0054] 1. Experimental method

[0055] The lipid-lowering and weight-reducing compositions prepared in Examples 1-9 were used as samples of the experimental group.

[0056] Take 110 170±20g healthy adult male SD rats and adapt to feeding for 1 week, then cut off the tip of the tail to take the tail vein blood, separate the serum, and use the kit to measure TC, TG, HDL-C, LDL-C as the basic value.

[0057] Divide into two groups randomly subsequently, blank group 10 are fed with commercially available basal feed; 100 high-fat groups are fed with commercially available high-fat feed; and 9 experimental groups, 9 experimental groups were fed with high-fat feed continuously (300mg / d / only), and the rest of the groups were fed with the same amount of distilled water, and were fed once a day at regular intervals. After 4 weeks of intervention, the tip of the tail was broken T...

Embodiment 11-14

[0074] Example 11-14 Lipid-lowering and weight-loss soft capsules

[0075] 1. This embodiment provides a series of fat-lowering and slimming soft capsules, the composition of which is shown in Table 7.

[0076] Table 7

[0077]

[0078] 2. The preparation process of soft capsules is as follows: figure 1 shown

[0079] S1. Mixing of soft capsule contents: Weigh tea oil, vegetable oil, beeswax, vitamin E, prebiotics and probiotic freeze-dried powder according to the formula, and mix them evenly with a mixer. The mixing time is 20min, and the temperature of the mixer is 25 ℃, ambient humidity 40%;

[0080] S2. Preparation of capsule material liquid: put glycerin, gelatin, and distilled water into a colloidal sol tank according to the formula, stir and dissolve at 60°C, vacuum degas, and filter through a 100-mesh sieve to obtain the capsule material liquid;

[0081] S3. The content obtained in S1 and the capsule material liquid obtained in S2 are prepared into capsules thro...

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Abstract

The invention discloses a lipid-lowering and weight-reducing tea oil composition and application thereof, a soft capsule and a preparation method of the soft capsule, the lipid-lowering and weight-reducing tea oil composition comprises tea oil, composite vegetable oil, prebiotics and probiotics in a weight ratio of (55-65): (5-15): (10-20): (10-20), and the composition proportion of fatty acid iseffectively improved by matching the tea oil with the composite vegetable oil. The lipid-lowering effect is greatly improved by matching with the probiotics and prebiotics, the soft capsule containingthe composition is further developed, the soft capsule contains the vegetable oil and the probiotics and prebiotics, the lipid-lowering effect is greatly enhanced, meanwhile, the raw material is richin source and wide in source and is easily available, and through improving the process, the probiotic activity is more stable, the shelf life of the product is prolonged, and the obtained lipid-lowering and weight-losing soft capsule is safe and free of side effects and can be eaten for a long time to prevent obesity.

Description

technical field [0001] The invention relates to the technical field of medicines, in particular to a lipid-lowering and weight-reducing tea oil composition and its application, a soft capsule and a preparation method thereof. Background technique [0002] Since 1975, the number of obese people in the world has nearly tripled. According to the World Health Organization, in 2016, more than 1.9 billion adults were overweight, of which more than 650 million were obese. At present, the prevalence of obesity in the Chinese population is also increasing year by year. From 2004 to 2014, the adult obesity rate increased from 3.3% to 14.0%, and the number of obese people has surpassed that of the United States. And a series of health problems caused by obesity seriously affect people's life. For example, obesity is a major risk factor for noncommunicable diseases, including cardiovascular disease, diabetes, musculoskeletal disorders, and certain cancers; moreover, the risk of develop...

Claims

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Application Information

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IPC IPC(8): A61K36/73A61P3/04A61P3/06A61K9/48A61K47/44A61K47/22A61K31/702A61K35/744A61K35/745A61K35/747A61K36/185A61K36/42A61K36/55A61K36/605
CPCA61K36/42A61K36/55A61K36/73A61K36/185A61K36/605A61K31/702A61K35/745A61K35/747A61K35/744A61K9/4858A61P3/06A61P3/04A61K2300/00
Inventor 吴雪辉肖希贤
Owner SOUTH CHINA AGRI UNIV
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