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Oral care product for resisting helicobacter pylori

An anti-Helicobacter pylori and oral care technology, applied in the field of daily chemicals, can solve problems such as repeated infection, incurable disease, repeated Hp infection, etc., and achieve a significant therapeutic effect

Inactive Publication Date: 2020-12-04
福州比格艾普科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Hp in the oral cavity can be transmitted through saliva, and can also repeatedly infect the stomach. Therefore, oral transmission can be carried out when the amount of Hp in the oral cavity reaches a certain threshold, which will further affect the treatment of Hp in the stomach, so that the cured patient is repeatedly infected with Hp in the stomach. The disease cannot be cured

Method used

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  • Oral care product for resisting helicobacter pylori
  • Oral care product for resisting helicobacter pylori

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] (1) Extraction: mix 15g of Radix Astragali, 5g of Forsythia, 10g of Radix Scutellariae, 4g of Glycyrrhiza licorice, grind to 20 mesh, mix with 1g of Mint, add 175g of water in total, cook at 80°C for 2 hours, filter to obtain the filtrate;

[0038] (2) Concentration: concentrating the filtrate under reduced pressure to a relative density of 1.2 and a water content of 10% to obtain a concentrated solution;

[0039] (3) Drying: The concentrated solution is spray-dried, the inlet temperature is 120°C, the outlet temperature is 50°C, and spraying forms a dry powder;

[0040] (4) Mixing: dry powder is mixed with 1g of lysozyme to obtain oral care water-soluble powder, and set aside;

[0041] Oral care water-soluble powder is added into 105g of water to dissolve, and prepared into oral care liquid, for subsequent use;

[0042] 50 volunteers: Patients with chronic gastritis or peptic ulcer confirmed by gastroscopy, no history of antibiotic treatment in the past half a year, n...

Embodiment 2

[0045] (1) Extraction: mix 25g of Radix Astragali, 15g of Forsythia, 20g of Radix Scutellariae, 8g of Radix Glycyrrhizae, grind to 60 mesh, mix with 5g of Peppermint, add 1095g of water in total, cook at 100°C for 4 hours, filter to obtain the filtrate;

[0046] (2) Concentration: concentrating the filtrate under reduced pressure to a relative density of 1.5 and a water content of 20% to obtain a concentrated solution;

[0047] (3) Drying: The concentrated solution is spray-dried, the inlet temperature is 140°C, the outlet temperature is 80°C, and sprays to form a dry powder;

[0048] (4) Mixing: dry powder is mixed with 2g of lysozyme to obtain oral care water-soluble powder, which is set aside;

[0049] Oral care water-soluble powder is added into 219g of water to dissolve, and prepared into oral care liquid, and set aside;

[0050] 50 volunteers: Patients with chronic gastritis or peptic ulcer confirmed by gastroscopy, no history of antibiotic treatment in the past half a ...

Embodiment 3

[0053] (1) Extraction: mix 20g of Radix Astragali, 10g of Forsythia, 15g of Radix Scutellariae, 6g of Licorice, grind to 30 mesh, mix with 3g of Mint, add 540g of water, cook at 90°C for 3 hours, filter to obtain the filtrate;

[0054] (2) Concentration: concentrating the filtrate under reduced pressure to a relative density of 1.3 and a water content of 15% to obtain a concentrated solution;

[0055] (3) Drying: The concentrated solution is spray-dried, the inlet temperature is 130°C, the outlet temperature is 65°C, and spraying forms a dry powder;

[0056] (4) Mixing: the dry powder is mixed with 1.5 g of lysozyme to obtain a mixed powder and a water-soluble oral care powder.

[0057] The oral care water-soluble powder is added into 162g of water for dissolving, and prepared into an oral care liquid for subsequent use;

[0058] 50 volunteers: Patients with chronic gastritis or peptic ulcer confirmed by gastroscopy, no history of antibiotic treatment in the past half a year,...

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Abstract

The invention discloses a composition for resisting helicobacter pylori, and belongs to the technical field of daily chemical products. The composition comprises astragalus membranaceus, forsythia suspensa, scutellaria baicalensis, licorice roots, mint and lysozyme. The invention further discloses a method for making the composition into an oral care product. By using the oral care product prepared by the invention, 95% of oral Hp detection results of helicobacter pylori patients can be converted from positive to negative within 14 days, and the oral care product has a remarkable treatment effect.

Description

technical field [0001] The invention belongs to the technical field of daily chemicals, and in particular relates to an oral care product against Helicobacter pylori. Background technique [0002] Helicobacter pylori (Helicobacter pylori), referred to as Hp. Helicobacter pylori is a highly infectious pathogenic bacteria. In 1983, Australian scholars Barry J.Marshall and Robin Warren J.Robin Warren isolated and detected Helicobacter pylori for the first time in gastric mucosal biopsies of gastritis patients. In 1989, Australian scholar Krajden detected HP in the dental plaque of the oral teeth of patients with gastritis, and confirmed that it was the same as Hp in the stomach from the molecular level. [0003] Helicobacter pylori has great damage to the human body: 90% of duodenal ulcers and 80% of gastric ulcers in the world are caused by Helicobacter pylori infection. Among patients with chronic active gastritis in my country, the detection rate of Helicobacter pylori is...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/66A61K8/02A61Q11/00A61Q17/00A61P31/02A61P1/02
CPCA61K8/9789A61K8/66A61K8/022A61Q11/00A61Q17/005A61P31/02A61P1/02A61K2800/592A61K2800/5922A61K2800/805
Inventor 禇英杰
Owner 福州比格艾普科技有限公司
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