Knowledge graph-based old medicine new use analysis method and system

A technology of knowledge graph and new use of old drugs, applied in the fields of chemical informatics and bioinformatics, can solve the problems of lack of experimental verification

Pending Publication Date: 2020-12-25
MINDRANK AI LTD
View PDF0 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, although they have been successfully applied to knowledge graph tasks such as question answering, information extraction, and named

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Knowledge graph-based old medicine new use analysis method and system
  • Knowledge graph-based old medicine new use analysis method and system
  • Knowledge graph-based old medicine new use analysis method and system

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0044] In the following description, the present invention is described with reference to various examples. One skilled in the art will recognize, however, that the various embodiments may be practiced without one or more of the specific details, or with other alternative and / or additional methods, materials, or components. In other instances, well-known structures, materials, or operations are not shown or described in detail so as not to obscure aspects of the various embodiments of the invention. Similarly, for purposes of explanation, specific quantities, materials and configurations are set forth in order to provide a thorough understanding of embodiments of the invention. However, the invention may be practiced without these specific details. Furthermore, it should be understood that the various embodiments shown in the drawings are illustrative representations and are not necessarily drawn to scale.

[0045] In this specification, reference to "one embodiment" or "the...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a knowledge graph-based old medicine new use analysis method. The method comprises the steps of obtaining a knowledge graph; extracting all disease entities, medicine entitiesand gene entities and relationships among the disease entities, the medicine entities and the gene entities in the knowledge graph; vectorizing all entities and relationships to obtain a feature vector of each entity and a feature vector of the relationship; determining one or more candidate machine learning models; training the candidate machine learning model; verifying and comparing the candidate machine learning models, and selecting an optimal machine learning model; and predicting a specific disease by applying the optimal model to obtain a plurality of medicine entities related to the specific disease.

Description

technical field [0001] The invention relates to the fields of chemical informatics and bioinformatics. Specifically, the present invention relates to a method and system for analyzing new uses of old drugs based on knowledge graphs. Background technique [0002] The biomedical knowledge graph is usually a multi-relational directed graph, in which nodes represent entities and edges represent relationships. The knowledge base of this graph structure has become a resource with great value and potential application value, which is helpful for precision medicine. and clinical decision support, which play an increasingly important role in healthcare practice and research. However, due to the usually large and noisy knowledge graphs constructed from biomedical data and the complexity and high knowledge requirements of downstream tasks, there are still many challenges in construction and application. [0003] The task of link prediction between entities is currently the most widel...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): G06F16/36G06N20/00G16H20/10G16H50/70
CPCG16H20/10G16H50/70G06F16/367G06N20/00
Inventor 牛张明郑双佳饶家华宋颖
Owner MINDRANK AI LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap