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Composition for treating cough, preparation method and preparation

A technology of composition and preparation, applied in the field of composition for treating cough, which can solve problems such as poor product stability, easy precipitation and low taste saturation, and achieve the effect of reducing time-consuming and consumables

Inactive Publication Date: 2021-02-23
广州白云山潘高寿药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the existing sugar-free oral liquid Chinese patent medicines in the pharmaceutical market use high-volume sweeteners such as steviol glycosides, sodium cyclamate, and aspartame instead of sucrose. Poor stability, easy to precipitate

Method used

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  • Composition for treating cough, preparation method and preparation
  • Composition for treating cough, preparation method and preparation
  • Composition for treating cough, preparation method and preparation

Examples

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preparation example Construction

[0024] A preparation method of the above composition, comprising the following steps:

[0025] (1) Take loquat leaves, 100 pectoralis, Peucedanum, Platycodon grandiflorum and Morus alba by weighing parts by weight, extract with water, filter, concentrate, and obtain a water-extracted concentrate;

[0026] (2) Filtrate the water-extracted concentrate, and mix the filtrate with the menthol, maltitol liquid or maltitol in parts by weight.

[0027] In some of these embodiments, in step (1), the extraction method is decoction; the extraction times are 2-3 times.

[0028] In some of these embodiments, the relative density of the water-extraction concentrate at 20° C. is 1.02-1.08.

[0029] A preparation for treating cough, which comprises the above composition and acceptable additives in the preparation.

[0030] In some of these embodiments, the formulation is a mixture.

[0031] In some of these embodiments, the additive includes at least one of essence and preservative.

Embodiment 1

[0038] Take water to extract the concentrated solution, filter to obtain clarified medicinal solution, add maltitol solution (450g maltitol solution, boil to dissolve, add 2.5g preservative) after mixing, add menthol 0.16g, almond essence 0.32g, red bayberry essence 0.13g, Add water to 1000ml and make. The total sugar content is less than 0.5% (the determination method of the total sugar content is: use the second acid hydrolysis method in GB 5009.8, refer to alcoholic beverages, but the first step pretreatment does not evaporate to 1 / 4 of the original volume, only boil about 5-10 minutes, remove a small amount of ethanol in the product, other operations are the same, only measure the amount of reducing sugar in the liquid after hydrolysis).

Embodiment 2

[0040] Take water to extract the concentrated solution, filter to obtain a clarified medicinal solution, add maltitol solution (450g maltitol solution, boil to dissolve, add 2.5g preservative) after mixing, add 0.5g citric acid, add menthol 0.16g, almond essence 0.32 g, 0.13g of red bayberry essence, add water to 1000ml, make. The total sugar content is less than 0.5%.

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Abstract

The invention relates to a composition for treating cough, a preparation method and a preparation. The composition is prepared from the following raw materials in parts by weight: 200-500 parts of maltitol liquid or 200-500 parts of maltitol, 120-140 parts of folium eriobotryae, 15-30 parts of radix stemonae, 10-20 parts of radix peucedani, 8-10 parts of platycodon grandiflorum, 8-10 parts of cortex mori radicis and 0.10-0.20 part of menthol. The composition for treating cough is low in sugar content, good in taste, clear in product and stable in quality.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a composition, a preparation method and a preparation for treating cough. Background technique [0002] Diabetes is a common and frequently-occurring disease, and it is also a major disease that endangers the health of the population. China is a big country with diabetes. In 2007, the number of people with diabetes was about 40 million, and its incidence rate is increasing year by year. If it is not controlled, it is predicted that it will reach 60 million by 2025, ranking second in the world (YANG SH, DOU KF, SONG WJ. Prevalence of diabetes among men and women in china [J]. N Engl J Med, 2010, 362(25): 2425-2426). According to the 2015 National Cardiovascular Disease Report, if based on previous diagnosis or fasting blood glucose / postprandial 2h blood glucose test results, the prevalence of diabetes in Chinese adults is 9.7%, and if reference is also made to the leve...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/904A61K9/00A61K47/26A61P11/14A61K31/045
CPCA61K9/0095A61K31/045A61K36/23A61K36/346A61K36/605A61K36/73A61K36/904A61K47/26A61K2236/331A61K2236/39A61K2236/51A61P11/14A61K2300/00
Inventor 杨东升林竹青陈世斌彭雅丹何雪平詹家辉沈翩
Owner 广州白云山潘高寿药业股份有限公司
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