1.7 mu m waveband non-diffraction light source biological imaging system with controllable coherence degree

A technology of biological imaging and coherence, which is applied in the field of optical imaging, can solve the problems of speckle noise with limited imaging depth and affect imaging quality, and achieve the effects of improving imaging quality and imaging speed, reducing speckle noise, and low absorption loss

Pending Publication Date: 2021-03-26
CHANGCHUN UNIV OF SCI & TECH
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Problems solved by technology

[0005] In order to solve the problem that when the light source images biological tissues rich in water, the imaging depth is limited by the absorption and scattering loss of water, and the high spatial coherence of the light source causes speckle noise, which affects the imaging quality, and proposes a coherent Biological imaging system with controllable 1.7μm band non-diffracting light source

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  • 1.7 mu m waveband non-diffraction light source biological imaging system with controllable coherence degree
  • 1.7 mu m waveband non-diffraction light source biological imaging system with controllable coherence degree

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Embodiment Construction

[0014] The present invention will be described in detail below in conjunction with the accompanying drawings and embodiments.

[0015] Such as figure 2 As shown, the 1.7 μm band non-diffracting light source biological imaging system with controllable coherence of the present invention includes a semiconductor laser 1, an erbium-doped fiber amplifier 2, an optical isolator 3, a fiber Bragg grating-4, and a double-clad thulium-doped optical fiber 5. Fiber Bragg grating 2 6, multimode fiber 7, fiber collimator 8, lens 1 9, pinhole 10, lens 2 11, dichroic mirror 12, polarizer 13, beam expander 14, computer 15, Spatial light modulator 16, prism 17, lens three 18, mirror 19, CCD camera 20, lens four 21, microscope objective lens 22 and translation stage 23.

[0016] Semiconductor laser 1, erbium-doped fiber amplifier 2, optical isolator 3, fiber Bragg grating 1 4, double-clad thulium-doped fiber 5, fiber Bragg grating 2 6, multimode fiber 7 and fiber collimator 8 are sequentially ...

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Abstract

The invention discloses a 1.7 mu m waveband non-diffraction light source biological imaging system with adjustable coherence degree, relates to the technical field of optical imaging, and solves the problems that when a light source images biological tissues rich in moisture, the imaging depth is limited due to absorption and scattering loss of water, speckle noise is caused by high spatial coherence degree of the light source, and the imaging quality is influenced. A semiconductor laser, aerbium-doped fiber amplifier, an optical isolator, a first fiber bragg grating, a double-cladding thulium-doped fiber, a second fiber bragg grating, a multimode fiber and a fiber collimator are in fiber connection in sequence. The optical fiber collimator, a first lens, a pinhole, a second lens, a dichroscope, a polarizing film, a light beam expander and a spatial light modulator are coaxially arranged in sequence, and the pinhole is formed in a focal plane between the first lens and the second lens;the computer is connected with the spatial light modulator through a cable; the spatial light modulator, the prism, the third lens and the reflector are coaxially arranged in sequence; the CCD camera, the fourth lens, the prism, the microscope objective and the translation stage are sequentially and coaxially arranged in the longitudinal direction.

Description

technical field [0001] The invention relates to the technical field of optical imaging, in particular to a 1.7 μm band non-diffracting light source biological imaging system with adjustable coherence. Background technique [0002] The 1.7μm band laser (1650nm-1750nm) is located in the third near-infrared (NIR3) optical window for biological imaging. The optical scattering energy loss in biological tissue is small, and the light in this band is located in the valley between the two water absorption peaks. The absorption rate of water in biological tissues is low, so the scattering energy loss is small. At the same time, the light in this waveband is also at the absorption peak of fat and collagen. When imaging fat in biological tissues, the imaging quality can be improved, and it has been widely used in biological imaging. application. [0003] Laser has the advantages of high coherence, high brightness, high directivity and monochromaticity, but in some applications, the hi...

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Application Information

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IPC IPC(8): G01N21/45G01N21/01
CPCG01N21/45G01N21/01G01N2201/06G01N2201/06113
Inventor 张鹏李奇何爽宁雨竹韩科选佟首峰
Owner CHANGCHUN UNIV OF SCI & TECH
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