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Belamcanda chinensis isolate and preparation method and application thereof

A technology of isolates and moisture, which is applied in the direction of medical preparations containing active ingredients, drug combinations, and pharmaceutical formulas, and can solve problems such as expensive prices, multiple adverse reactions, and limited therapeutic effects

Inactive Publication Date: 2021-05-25
北京理工亘舒科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, western medicines are commonly used to treat hyperlipidemia and hyperglycemia. These western medicines are not only expensive, but most of them are hormonal drugs, which have limited therapeutic effects and many adverse reactions.

Method used

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  • Belamcanda chinensis isolate and preparation method and application thereof
  • Belamcanda chinensis isolate and preparation method and application thereof
  • Belamcanda chinensis isolate and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Weigh 500g of medicinal material powder, add water at 100°C and heat and reflux water extraction for 3 times, each time for 30 minutes, wherein the material-liquid ratio of medicinal material powder (g) to water (ml) is 1:15, 1:10, 1 : 10, the water extracts were combined, filtered, concentrated under reduced pressure to a certain volume, added absolute ethanol to adjust the ethanol concentration to 70%, ethanol precipitation 2 times, and collected the supernatant solution to obtain a dry raw material solution. Add 0.1mol / L NaOH to the dried raw material solution to adjust the pH value of the dried raw material solution to 6. Add 0.1mol / L HCl to the WA30 resin to adjust the pH value to 6, and put the WA30 resin on the column. The shot-dried raw material solution is loaded on the column at a flow rate of 4BV / h, and the sample effluent that flows out after the shot-dried raw material solution is loaded on the column is collected. After the sample is loaded, water is conti...

Embodiment 2

[0029] The three-time solid-liquid ratios of the medicinal material powder and water in Example 1 were all adjusted to 1:20, and the rest of the operation steps were the same as in Example 1 to obtain the dry isolate. The yield of the isolate was measured, and the effect of the isolate on lowering blood sugar and fat was investigated.

Embodiment 3

[0031] The ratio of solid to liquid of the medicinal material powder and water in Example 1 was adjusted to 1:8, and the rest of the operation steps were the same as in Example 1 to obtain the dry isolate. The yield of the isolate was measured, and the effect of the isolate on lowering blood sugar and fat was investigated.

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PUM

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Abstract

The invention provides a preparation method of a belamcanda chinensis isolate. The preparation method comprises the following steps: 1, extracting a rhizoma belamcandae raw material to obtain a rhizoma belamcandae raw material solution; 2, loading the blackberry lily raw material liquid on a column, and enabling the blackberry lily raw material liquid to pass through an ion exchange resin column; 3, carrying out water washing and elution on the ion exchange resin column, and collecting an eluent; and 4, removing moisture in the collected liquid to obtain the belamcanda chinensis isolate. The invention further provides the belamcanda chinensis isolate obtained according to the preparation method and application of the belamcanda chinensis isolate in preparation of sugar-reducing and lipid-reducing products, and the belamcanda chinensis isolate has important significance in development of sugar-reducing and lipid-reducing natural health-care foods and medicines.

Description

technical field [0001] The invention relates to a shegan isolate, a preparation method thereof and an application of the shegan isolate in preparing blood sugar-lowering and lipid-lowering medicines, belonging to the processing field of traditional Chinese medicines. Background technique [0002] With the rapid development of the country's modernization, people's living standards continue to improve, and the diet structure has changed, manifested as: high calorie, high oil, high alcohol, fast, low fiber, fiber deficiency, plus the inability to Avoid pesticide residues and heavy metals that accompany food. All these unhealthy eating behaviors are the main reason for the sharp increase in the phenomenon of "three highs". The symptoms of "three highs" not only bring a lot of inconvenience to daily life, but are also the main factors leading to cardiovascular diseases. Coupled with the ever-increasing pressure of life and work, smoking and drinking, and constant socializing, hy...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61P3/06A61P3/10A61K127/00A61K135/00
CPCA61K36/88A61K2236/331A61K2236/55A61P3/06A61P3/10
Inventor 邓玉林李汝鑫辛念孙俐丽戴荣继
Owner 北京理工亘舒科技有限公司
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