Preparation method of microecologically balanced probiotic microspheres based on traction structure

A technology of ecological balance and prebiotics, applied in the field of skin care, can solve problems such as the difficulty of microbial barrier repair, and achieve the effect of increasing the protective effect and improving the protective effect

Active Publication Date: 2021-06-01
GUANGDONG IND TECHN COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Aiming at the problems in the prior art, the technical problem to be solved by the present invention is to provide a preparation method of prebiotic microspheres based on the micro-ecological balance of the traction structure to solve the problem of difficult microbial barrier repair

Method used

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  • Preparation method of microecologically balanced probiotic microspheres based on traction structure
  • Preparation method of microecologically balanced probiotic microspheres based on traction structure

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Effect test

Embodiment 1

[0021] A prebiotic microsphere based on the micro-ecological balance of the traction structure. The prebiotic compound is used as the active core layer, and the multi-layer composite hyaluronic acid is used as the coating shell to form the prebiotic composite microsphere. The multi-layer composite is transparent Hyaluronic acid contains tetrahydromethyl pyrimidine carboxylic acid.

[0022] The prebiotic microspheres are stored in glycerin, and the mass ratio of the glycerol to the prebiotic milk balls is 15:1.

[0023] In order to improve the viscosity of glycerin, carbomer is added in an amount of 0.01% of the glycerin mass, and the carbomer adopts carbomer 940.

[0024] The preparation method of the prebiotic microspheres comprises the following steps: step 1, adding hyaluronic acid to distilled water for low-temperature ultrasonic dispersion to form a solution, and then constant temperature granulation to form microsphere particles; the concentration of the hyaluronic acid ...

Embodiment 2

[0029] A prebiotic microsphere based on the micro-ecological balance of the traction structure. The prebiotic compound is used as the active core layer, and the multi-layer composite hyaluronic acid is used as the coating shell to form the prebiotic composite microsphere. The multi-layer composite is transparent The hyaluronic acid contains tetrahydromethylpyrimidine carboxylic acid, and the prebiotic microspheres are stored in glycerin, and the mass ratio of the glycerol to the prebiotic milk balls is 15:4.

[0030] In order to improve the viscosity of glycerin, carbomer is added in an amount of 0.05% of the glycerin mass, and the carbomer adopts carbomer 934.

[0031] The preparation method of the prebiotic microspheres comprises the following steps: step 1, adding hyaluronic acid to distilled water for low-temperature ultrasonic dispersion to form a solution, and then constant temperature granulation to form microsphere particles; the concentration of the hyaluronic acid in ...

Embodiment 3

[0036] A prebiotic microsphere based on the micro-ecological balance of the traction structure. The prebiotic compound is used as the active core layer, and the multi-layer composite hyaluronic acid is used as the coating shell to form the prebiotic composite microsphere. The multi-layer composite is transparent The hyaluronic acid contains tetrahydromethyl pyrimidine carboxylic acid, and the prebiotic microspheres are stored in glycerin, and the mass ratio of the glycerol to the prebiotic milk balls is 5:1.

[0037] The preparation method of the prebiotic microspheres comprises the following steps: step 1, adding hyaluronic acid to distilled water for low-temperature ultrasonic dispersion to form a solution, and then constant temperature granulation to form microsphere particles; the concentration of the hyaluronic acid in distilled water is 50g / L, the temperature of low-temperature ultrasound is 15°C, and the ultrasonic dispersion is 70kHz; the temperature of the constant te...

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Abstract

The invention discloses a preparation method of microecological balance probiotic microspheres based on a traction structure, probiotic composite microspheres are formed by taking a probiotic compound as an active core layer and taking multilayer composite hyaluronic acid as a coating shell, the multilayer composite hyaluronic acid contains tetrahydromethylpyrimidine carboxylic acid, and the specific preparation method is provided. According to the invention, the problem of difficulty in repairing a microbial barrier is solved, a physical-biological dual repairing system is formed by utilizing a physical water retention system of the probiotic compound and the hyaluronic acid, the protection effect of skin is greatly improved, and meanwhile, a physical repairing system of a water anion system is formed by utilizing the tetrahydromethylpyrimidine carboxylic acid, so that the protection effect is greatly improved.

Description

technical field [0001] The invention relates to a preparation method of prebiotic microspheres based on micro-ecological balance of traction structure, belonging to the field of skin care. Background technique [0002] As we all know, the skin, as the largest organ of the human body, protects our body against the external environment. The stratum corneum in the epidermis is composed of a layer of dense cells. Because of its compact structure, it plays an extremely important barrier role for the human body. With the development and improvement of technology, the layering of the skin is becoming more and more detailed. In our daily skin care, in addition to the need to pay attention to the physical barrier of the skin that is often in contact with the skin, the newly introduced skin microbial barrier is also related to our skin health. Inseparable. [0003] As the human body surface barrier-skin, there are often some microorganisms, some of which can parasitize on the human ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/99A61K8/34A61K8/49A61K8/60A61K8/73A61K8/81A61K8/92A61K8/11A61Q19/00A61Q17/00
CPCA61K8/735A61K8/4953A61K8/11A61K8/345A61Q19/005A61Q17/005A61K8/8147A61K8/60A61K8/73A61K8/99A61K8/922A61K2800/5922Y02A50/30
Inventor 徐梦漪郑丹阳
Owner GUANGDONG IND TECHN COLLEGE
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