A kind of method for ion-pair chromatography to measure related substances in 6-bromohexyltrimethylammonium bromide
A technology of bromohexyltrimethylammonium bromide and ion-pair chromatography, which is applied in the field of ion chromatography, can solve problems such as long analysis time, complicated operation, and inability to measure, and achieve good reproducibility, simple method, and low test cost. low effect
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0045] Example 1 The eluent conditions of 6-bromohexyltrimethylammonium bromide and hexamethylamine bromide
[0046] The ion chromatograph is used for detection, and the specific steps include:
[0047] (1) prepare standard stock solutions of 6-bromohexyltrimethylammonium bromide and hexamethylammonium bromide
[0048] Precisely weigh 102.04mg of 6-bromohexyltrimethylammonium bromide standard (purity 98%) in a 100mL volumetric flask, dissolve in ultrapure water, make up to the mark, shake well, and prepare 1000mg / L 6-bromo Hexyltrimethylammonium bromide standard stock solution.
[0049] Precisely weigh 101.01 mg of hexamethylammonium bromide standard product (purity 99%) into a 100 mL volumetric flask, dissolve in ultrapure water, make up to the mark, shake well, and prepare a 1000 mg / L hexamethylammonium bromide standard stock solution.
[0050] (2) prepare a mixed standard solution of 6-bromohexyltrimethylammonium bromide and hexamethylammonium bromide
[0051] Precisely ...
Embodiment 2
[0063] Example 2 Linear parameters and detection limits of 6-bromohexyltrimethylammonium bromide and hexamethylamine bromide
[0064] The ion chromatograph is used for detection, and the specific steps include:
[0065] (1) prepare standard stock solutions of 6-bromohexyltrimethylammonium bromide and hexamethylammonium bromide
[0066] The preparation of 6-bromohexyltrimethylammonium bromide and hexamethylammonium bromide standard stock solution is the same as that in Example 1.
[0067] (2) Preparation of 6-bromohexyltrimethylammonium bromide and hexamethylammonium bromide standard solution series
[0068] Precisely pipette 0.1mL, 0.5mL, 1.0mL, 2.5mL, 5.0mL of 6-bromohexyltrimethylammonium bromide standard stock solution into a 10mL volumetric flask, dissolve with ultrapure water, make up to the mark, shake to obtain a series of 6-bromohexyltrimethylammonium bromide standard solutions with concentrations of 10mg / L, 50mg / L, 100mg / L, 250mg / L and 500mg / L respectively.
[0069...
Embodiment 3
[0081] Embodiment 3 A kind of method that utilizes ion pair chromatography to detect the purity of 6-bromohexyl trimethyl ammonium bromide adopts ion chromatograph to detect, the external standard method single-point quantitative analysis, concrete steps include:
[0082] (1) Preparation of 6-bromohexyltrimethylammonium bromide reference substance and sample solution
[0083] Weigh about 50mg of 6-bromohexyltrimethylammonium bromide standard (purity 98%) and 1#, 2# and samples in a 100mL volumetric flask, dissolve with ultrapure water, make up to the mark, shake well, That is, the standard and sample solutions are obtained.
[0084] (2) Setting of ion-pair chromatography conditions
[0085] The adopted chromatographic conditions are the same as those in Example 1, except that the gradient elution is performed, and the gradient program is shown in Table 2.
[0086](3) According to the above chromatographic conditions, after the baseline of the instrument is balanced, take the...
PUM
Property | Measurement | Unit |
---|---|---|
length | aaaaa | aaaaa |
particle size | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com