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Method for measuring stool consistency and method for evaluating stool state using same

An evaluation method, technology of feces, applied in the direction of testing material hardness, measuring device, strength characteristics, etc.

Pending Publication Date: 2021-07-23
YAKULT HONSHA KK
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, this method has a problem that the amount of feces needs to be 50 g or more (thus, about 30% of feces are not subject to measurement)

Method used

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  • Method for measuring stool consistency and method for evaluating stool state using same
  • Method for measuring stool consistency and method for evaluating stool state using same
  • Method for measuring stool consistency and method for evaluating stool state using same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Probe selection:

[0043] (1) The types of probes used for the measurement of the hardness of stools were studied using the simulated stool samples described below as specimens. Clay, meat stuffing, paste as solid samples figure 1 (A) After shaping with a spatula, it was used for hardness measurement. Greek yogurt and plain yogurt as liquid samples were put into a 100-ml capacity cylindrical plastic container (manufactured by SARSTED, model number: 75.562.105), and then used for hardness measurement. First, for the purpose of selecting a measurement probe that is less susceptible to the influence of the difference in sample size, the probe described below was used (the shape of the probe is shown in figure 2 ) and use a texture analyzer (TA.XT Express Enhanced Texture Analyzer (Stable Micro Systems)) to measure homogeneous clays with different sizes ( figure 1 (A), assuming the hardness of feces with a BS score of 1 to 2).

[0044]

[0045] Clay (Play-Doh, Hasbro...

Embodiment 2

[0071] Preparation of stool samples:

[0072] It is considered that even for feces excreted at the same time, there is a possibility that the results may vary greatly depending on the difference in the fecal mass and its location where the hardness is measured. In such a case, it is necessary to examine the measurement by homogenizing stool in advance.

[0073] Therefore, the difference in hardness between different parts of a single fecal mass was first verified. As the feces, the feces (total 32 specimens) collected from three healthy adults were used. The total amount of feces excreted per defecation was recovered to FECOTAINER (registered trademark) (AT Medical Company). By using the texture analyzer of the 6mm cylindrical probe selected in Example 1, the "front part (Head)" of a plurality of fecal masses discharged while maintaining the sausage-like shape was measured under the same conditions as in Example 1, The hardness of the Body and Tail. Its results are shown i...

Embodiment 3

[0078] Correlation with BS score:

[0079] 40 healthy adult men and women over the age of 18 were used. Regarding all defecation during the defecation period, the subjects recorded the time, whether there was any strain during defecation, and whether there was a feeling of fullness after defecating in a diary. At the same time, the subjects recovered the total amount of excreted feces into a plastic container for excrement (manufactured by Medline, product name: 2-Piece SpecimenCollector, model: DYND36500), and recorded in the diary the results obtained by observing the properties of the feces. result. The mean ± standard deviation of stool weight was 87.25 ± 59.46 g. For the evaluation of stool properties, using the BS score, the graph of the BS recorded in the diary was compared with the recovered stool, and the score considered to be the most appropriate to illustrate the schematic diagram of its shape was recorded.

[0080] After the subject recorded the BS score, the f...

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Abstract

To provide a method capable of physically and objectively evaluating the consistency or state of a stool, the present invention provides a method for measuring stool consistency with a texture analyzer provided with a probe, the method being characterized in that the probe has a shape that is capable of measuring the consistency of a stool in liquid and solid form.

Description

technical field [0001] The present invention relates to a method for measuring the hardness of feces and a method for evaluating the state of feces using the method. Background technique [0002] Evaluation of the state of feces is useful for managing physical conditions and investigating the influence of test substances such as drugs. [0003] So far, the BS (Bristol Stool Form Scale) score has been used as an index for evaluating the state of stool (Non-Patent Document 1). However, the BS score is a scale established as an index of bowel transit time for subjective judgment by the evaluator, so it is difficult to completely exclude the psychological influence of the evaluator, and the hardness and appearance of stool may not always match. [0004] In addition, as other indicators for evaluating the state of feces, a method for evaluating the hardness of feces using a penetrometer (a device that freely falls a probe of a certain weight from the surface of a sample to measu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N3/40G01N33/483
CPCG01N33/483G01N11/10G01N3/40G01N2203/0076G01N2203/0012G01N2203/0676G01N33/5088
Inventor 秋山拓哉松田一乘藤本淳治
Owner YAKULT HONSHA KK
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