Methods of treating acute stress disorder and posttraumatic stress disorder

A post-traumatic stress and trauma technology, applied in the direction of pharmaceutical formulations, organic active ingredients, medical preparations containing active ingredients, etc., can solve the problems of ASD or PTSD that are difficult to achieve and drugs are ineffective
CN113194935APending Publication Date: 2021-07-30TONIX PHARMA HLDG LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
TONIX PHARMA HLDG LTD
Publication Date
2021-07-30

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Abstract

This invention relates to methods of treating posttraumatic stress disorder and acute stress disorder using pharmaceutical compositions comprising cyclobenzaprine, amitriptyline, or pharmaceutically acceptable salts thereof. In particular, it relates to methods of treating posttraumatic stress disorder or one or more symptoms thereof in a subject who has experienced a traumatic event less than or equal to about 9 years prior to the commencement or treatment. It also relates to methods of treating acute stress disorder or one or more symptoms thereof in a subject who has experienced a traumatic event less than or equal to about 1 month prior to the commencement of treatment.
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Description

technical field

[0001] This application claims priority to and benefit of U.S. Provisional Patent Application 62 / 720,063, filed August 20, 2018, the contents and disclosure of which are incorporated herein by reference in their entirety.

[0002] The present application relates to methods for treating acute stress disorder, post-traumatic stress disorder and related symptoms thereof. Of particular interest are methods comprising administering to a subject a pharmaceutical composition comprising cyclobenzaprine, amitriptyline, or a pharmaceutically acceptable salt thereof, the subject initially Have experienced PTSD or ASD-induced traumatic events less than or equal to about 9 years prior to commencement of treatment. Background technique

[0003] The development of posttraumatic stress disorder (PTSD) is triggered by exposure to traumatic events and leads to symptoms including: difficulty sleeping, nightmares, irritability, difficulty concentrating, hypervigilance, and pers...

Claims

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