Colostrum nano-peptide with natural biological activity as well as preparation method and application thereof

A bioactive, colostrum technology, applied in the biological field, can solve problems such as the lack of development of colostrum extract

Pending Publication Date: 2021-09-10
HEILONGJIANG KANPURE BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the limitations of existing technologies and processes, the modern industry has never developed a colostrum extrac

Method used

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  • Colostrum nano-peptide with natural biological activity as well as preparation method and application thereof
  • Colostrum nano-peptide with natural biological activity as well as preparation method and application thereof
  • Colostrum nano-peptide with natural biological activity as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Embodiment 1 has the preparation of the colostrum nanopeptide of natural biological activity and related products thereof

[0033] The method flowchart of embodiment 1 of the present invention is as follows figure 1 As shown, it specifically includes the following steps:

[0034] (1) Collect colostrum within 48 hours after calving of healthy dairy cows, store and transport in cold storage;

[0035] (2) The colostrum is centrifuged in a continuous disc centrifuge at 40°C to 45°C at 5000rpm to remove fat and obtain defatted colostrum;

[0036] (3) The defatted colostrum is ultrafiltered by a filter membrane with a membrane pore size of 100KD to obtain the colostrum;

[0037] (4) Use lactic acid to adjust the pH of the colostrum to 5.4-5.6, let it stand for 15 minutes, then adjust the pH of the colostrum to 3.9, and bathe in water at 40°C for 150 minutes; then use a disc centrifuge at 5000rpm to remove the precipitate and obtain Liquid-I ;

[0038] (5) Adjust the pH of...

Embodiment 2

[0045] Embodiment 2 has the preparation of the colostrum nanopeptide of natural biological activity and related products thereof

[0046] The method flowchart of embodiment 2 of the present invention is as follows figure 2 As shown, it specifically includes the following steps:

[0047] (1) Collect colostrum within 72 hours after calving of healthy dairy cows, store and transport in cold storage;

[0048] (2) The colostrum is centrifuged in a continuous disc centrifuge at 40°C to 45°C at 5000rpm to remove fat and obtain defatted colostrum;

[0049] (3) The defatted colostrum is ultra-filtered with a filter membrane with a membrane pore size of 80KD to obtain the colostrum;

[0050] (4) Use lactic acid to adjust the pH of the colostrum to 5.4-5.6, let it stand for 15 minutes, then adjust the pH of the colostrum to 3.9, and bathe in water at 40°C for 150 minutes; then use a disc centrifuge at 5000rpm to remove the precipitate and obtain Liquid-I ;

[0051] (5) Adjust the pH o...

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Abstract

The invention discloses a colostrum nano-peptide with natural biological activity as well as a preparation method and application thereof. According to the method, colostrum within 72 hours after healthy dairy livestock calves is used as a raw material, a colostrum nano-peptide-enriched product is obtained through the steps of centrifugation, ultrafiltration, pH adjustment, enzymolysis, nanofiltration and the like, and main components of the colostrum nano-peptide-enriched product are proline-enriched polypeptide, insulin-like growth factor-1, epidermal growth factors and transforming growth factors. The product can be further prepared into various foods or daily chemical products, for example, sterile liquid oral liquid, beverages and powdery products are prepared to achieve the effects of regulating immunity, promoting bone growth, improving gastrointestinal tracts, promoting cognitive development and the like, or the product is added into a cosmetic matrix to be prepared into a skin care product to achieve the effects of improving epidermis nutrition, delaying skin aging, anti-wrinkling, whitening and the like, or the product is added into a toothpaste matrix to be prepared into toothpaste to achieve the effects of rapidly promoting cell proliferation, repairing oral cavity micro-injury and the like, or the product is added into a shampoo matrix to be prepared into anti-hair-loss and hair-strengthening shampoo.

Description

technical field [0001] The invention relates to a colostrum nanopeptide with natural biological activity, a preparation method and application thereof. The invention belongs to the field of biotechnology. Background technique [0002] Colostrum is the first mouthful of natural perfection that nature creates for new life. Colostrum itself has been proven to be a natural aggregate of hundreds of "primary nutrients", such as high protein, rich vitamins, low lactose and other substances. The direction of human use of bovine colostrum is not to obtain the basic nutrition in it, but to focus on how to improve the efficacy of immune function factors in colostrum, some of which are well-known functional factors such as immunoglobulin IgG and lactoferrin , play a role in improving human immunity, improving gastrointestinal tract and other health care functions. [0003] At present, colostrum products are still in the rough processing stage. The food industry only degreases colostr...

Claims

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Application Information

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IPC IPC(8): C07K1/14C07K1/36C07K1/34C07K1/30A61K8/64A61Q19/00A61Q19/08A61Q19/02A61Q11/00A61Q5/02A61Q7/00A23L2/02A23L2/52A23L33/18A23L33/15
CPCC07K1/145C07K1/36C07K1/34C07K1/30A61K8/64A61Q19/00A61Q19/08A61Q19/02A61Q11/00A61Q5/02A61Q7/00A23L2/02A23L2/52A23L33/18A23L33/15A61K2800/413A23V2002/00A23V2200/324A23V2200/306A23V2200/32A23V2200/322A23V2250/55A23V2250/70
Inventor 赵红宇周盛华李学琳景志刚王春柳关文凤黄馨菊
Owner HEILONGJIANG KANPURE BIOTECH
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