Natural extraction compound with acne removing effect and preparation method and application thereof
It is a natural extraction and compound technology, which is applied in medical preparations containing active ingredients, preparations for skin care, drug combinations, etc., and can solve problems such as large side effects, serious environmental pollution, and irregular skin metabolism.
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Embodiment 1
[0050] A natural extract compound with anti-acne effect. The plant extract compound is made of the following raw materials in parts by weight: 90 parts of epiphyllum, 90 parts of emblica, 40 parts of golden camellia, and 40 parts of golden flower tea , 30 parts of safflower, 50 parts of loquat leaves, 50 parts of centella asiatica, 70 parts of white willow bark, 70 parts of Magnolia officinalis, 45 parts of blue ear grass, 45 parts of sophora flavescens, 45 parts of purslane, olive leaves 70 parts and American mint leaves 25 parts.
Embodiment 2
[0051] Embodiment 2: safety test
[0052] 1. Three groups of rabbits (4 in each group, 12 in total) were subtracted from the back part of the hair, and the skin was exposed, and the natural extraction compound of Example 1 and Comparative Example 1, 2 was applied to the exposed part of the skin for one hour. After observing the results, compared with the unapplied area, there was no erythema or edema, indicating that there was no irritation and allergic reaction. According to the above operation, continuous observation for 15 days, the results are consistent.
[0053] 2. Apply the natural extract compound of Example 1 and Comparative Examples 1 and 2 on the hands of three groups of volunteer subjects (20 people in each group, 60 people in total), and observe every 6 hours within 0-48h Once, there was no redness, rash and blistering, and no adverse reactions were found.
[0054] Tests have proved that the natural extract complex provided by the invention is non-irritating and...
Embodiment 3
[0056] Select 90 volunteer subjects aged 20-50, 50 females and 40 males. The volunteers all have obvious acne on the face, no history of skin allergies, and can cooperate well with the test. In the trial During this period, you can maintain a good life schedule and eating habits. The volunteer subjects were randomly divided into 3 groups, 30 people in each group, and the natural extract compound of Example 1 and Comparative Examples 1 and 2 were applied to the acne-prone areas of the face, twice a day, once in the morning and once in the evening. Gently massage until absorbed, apply it continuously for 30 days, and observe the effect, the results are shown in Table 1. The effect evaluation is as follows:
[0057] Significant effect: the skin lesions basically subsided, and a small amount of acne and pimples remained;
[0058] Effective: skin lesions improved;
[0059] Ineffective: the skin lesions did not improve, or even aggravated.
[0060] Table 1 Acne-removing effect o...
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