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Soothing and desensitization composition and application thereof

A composition and soothing technology, applied in the field of skin care products, can solve the problems that have not been specifically addressed, and achieve the effects of reducing transdermal water loss rate, reducing anti-inflammation, and reducing redness, swelling, itching and pain

Pending Publication Date: 2021-09-28
DOCTOR PLANT GUANGDONG BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The technical problem to be solved by the present invention is to overcome that most of the existing anti-inflammatory and soothing repairing compositions are aimed at sensitive problems caused by inflammation, and there is no specific solution to the skin problems caused by surfactants SLS, retinol derivatives, etc. Defects and deficiencies of sensitive problems, providing a soothing and desensitizing composition, through the synergistic effect of specific saffron extract, Ophiopogon japonicus root extract and Sophora flavescens root extract, the active ingredients of polysaccharides and flavonoids are effective Repairs the skin barrier, relieves the onset of skin inflammation, inhibits the release of histamine, and effectively soothes the discomfort of sensitive skin, especially the sensitivity and discomfort caused by retinol and its derivatives

Method used

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  • Soothing and desensitization composition and application thereof
  • Soothing and desensitization composition and application thereof
  • Soothing and desensitization composition and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0058] A composition for soothing and desensitizing, in parts by weight, comprising the following components:

[0059] 3 parts of saffron extract; 4 parts of Ophiopogon japonicus root extract; 4 parts of Sophora flavescens root extract; 8 parts of D-panthenol. Wherein the saffron extract saffron extract is yellow or brown liquid, the density is 0.95-1.05, the mass content of dry extract is 0.5-2.0%, wherein the mass content of total flavonoids is ≥0.3g / L, and the mass content of total polysaccharides is ≥4.0g / L , pH value is 4.0~6.0.

[0060] Ophiopogon japonicus root extract contains polysaccharides and Ophiopogon japonicus saponins.

[0061] Sophora flavescens root extract contains alkaloids and flavonoids.

Embodiment 2

[0063] A composition for soothing and desensitizing, in parts by weight, comprising the following components:

[0064] 5 parts of saffron extract; 5 parts of Ophiopogon japonicus root extract; 5 parts of Sophora flavescens root extract; 10 parts of D-panthenol.

[0065] Wherein the saffron extract saffron extract is yellow or brown liquid, the density is 0.95-1.05, the mass content of dry extract is 0.5-2.0%, wherein the mass content of total flavonoids is ≥0.3g / L, and the mass content of total polysaccharides is ≥4.0g / L , pH value is 4.0~6.0.

[0066] Ophiopogon japonicus root extract contains polysaccharides and Ophiopogon japonicus saponins.

[0067] Sophora flavescens root extract contains alkaloids and flavonoids.

Embodiment 3

[0069] A composition for soothing and desensitizing, in parts by weight, comprising the following components:

[0070] 4 parts of saffron extract; 1 part of Ophiopogon japonicus root extract; 3 parts of Sophora flavescens root extract; 5 parts of D-panthenol. Wherein the saffron extract saffron extract is yellow or brown liquid, the density is 0.95-1.05, the mass content of dry extract is 0.5-2.0%, wherein the mass content of total flavonoids is ≥0.3g / L, and the mass content of total polysaccharides is ≥4.0g / L , pH value is 4.0~6.0.

[0071] Ophiopogon japonicus root extract contains polysaccharides and Ophiopogon japonicus saponins.

[0072] Sophora flavescens root extract contains alkaloids and flavonoids.

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Abstract

The invention discloses a soothing and desensitization composition and application thereof, and belongs to the technical field of skin care products. The soothing and desensitization composition is prepared from the following components in parts by weight: 0.1 to 5 parts of saffron crocus extract; 0.1-5 parts of a radix ophiopogonis root extract; 0.1-5 parts of a radix sophorae flavescentis extract; and 0.1 to 10 parts of D-panthenol. Carbonylation modified flavone and polysaccharide substances in the saffron crocus extract in the soothing and desensitization composition have good anti-free radical activity and anti-inflammatory activity, steroidal saponin in the radix ophiopogonis root extract can well inhibit histamine, THF-alpha, IL-6 and metal matrix protease, anti-inflammation can be well achieved, skin stress reaction can be well reduced. Alkaloid and flavonoid compounds in the radix sophorae flavescentis extract can inhibit vasodilatation and activate body immunocompetence, and by combining with D-panthenol with a moisturizing effect, a synergistic effect is achieved, stimulation brought by a surfactant SLS, a retinol derivative and the like can be effectively relieved, a damaged barrier can be repaired, and the sensitive degree of sensitive skin can be reduced.

Description

technical field [0001] The invention relates to the technical field of skin care products, more specifically, to a soothing and allergy-reducing composition and its application. Background technique [0002] When the skin is irritated, there will be itching, tingling, peeling, scaling, redness and swelling. Sensitive muscles have a stronger tolerance to stimulation, mainly manifested as poor skin tolerance and strong sensation. Studies have shown that the transepidermal water loss TEWL of sensitive skin is significantly higher than that of normal skin, which is manifested by damaged skin barrier. At the same time, due to the damaged barrier, it is more likely to be irritated, which causes skin inflammation and blood vessel dilation, and redness occurs. Air pollution (mainly smog), staying up late, anxiety, insufficient sun protection, excessive skin care, plastic surgery, excessive makeup, irritating food, excessive use of screens and other factors will all bring certain s...

Claims

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Application Information

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IPC IPC(8): A61K8/9794A61K8/9789A61K8/42A61Q19/00
CPCA61K8/9794A61K8/9789A61K8/42A61Q19/005A61Q19/00A61K2800/5922A61K2800/782
Inventor 郭文姣李嘉怡刘裕娇贺锐
Owner DOCTOR PLANT GUANGDONG BIOTECHNOLOGY CO LTD
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