Pharmaceutical composition for treating oral ulcer as well as preparation method and application thereof

The technology of oral ulcer and composition is applied in the field of pharmaceutical composition for treating oral ulcer and its preparation field, and can solve the problems of causing oral cancer, recurrent attacks, lupus erythematosus and the like

Pending Publication Date: 2021-11-09
SICHUAN TIANFU FINE CHEM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

And because most oral ulcers will disappear on their own within a week or two, people generally do not pay attention to them. However, oral ulcers caused by fungi or systemic lesions will recur if not treated, and those who do not heal for a long time , may cause systemic lupus erythematosus, and may also cause oral cancer

Method used

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  • Pharmaceutical composition for treating oral ulcer as well as preparation method and application thereof
  • Pharmaceutical composition for treating oral ulcer as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] (1) Take raw materials according to Table 1;

[0039] Table 1

[0040] Scutellaria baicalensis 100g propolis 100g coptis 100g oak bark 80g cork 100g tea 50g lotus root powder 150g Asarum 30g Galla 300g Atractylodes 20g pandan bean 200g Chlorhexidine acetate 150g honeysuckle 100g

[0041]Excipients: calcium powder 18000g, silicon dioxide 18000g, potassium nitrate 6000g, carboxymethyl cellulose 600g, glycerin 12000g, sodium lauryl sulfate 1800g, SM gel 600g, sorbitol 6000g, mint essence 600g.

[0042] (2) Mix Sanhuang, gallnut, honeysuckle, asarum and Atractylodes macrocephala with water and decoct twice, add 6 times the amount of water to decoct for 2 hours for the first time, separate the filtrate, add 4 times the amount of water to the filter residue and decoct for 2 hours for the second time, Separate the filtrate, combine the two decoctions, filter, and concentrate the filtrate to a thick paste ...

Embodiment 2

[0048] With embodiment 1, difference is, take raw material according to table 2;

[0049] Table 2

[0050] Scutellaria baicalensis 66.7g propolis 100g coptis 66.7g oak bark 50g cork 66.7g tea 50g lotus root powder 150g Asarum 30g Galla 300g Atractylodes 10g pandan bean 100g Chlorhexidine acetate 50g honeysuckle 100g

Embodiment 3

[0052] With embodiment 1, difference is, take raw material according to table 3;

[0053] table 3

[0054] Scutellaria baicalensis 166.7g propolis 200g coptis 166.7g oak bark 80g cork 166.7g tea 100g lotus root powder 200g Asarum 50g Galla 500g Atractylodes 20g pandan bean 200g Chlorhexidine acetate 300g honeysuckle 200g

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Abstract

The invention discloses a pharmaceutical composition for treating oral ulcer as well as a preparation method and an application thereof, and belongs to the technical field of pharmaceutical compositions. The pharmaceutical composition for treating oral ulcer comprises the following raw materials: 20-50 parts of a mixture of scutellaria baicalensis, rhizoma coptidis and golden cypress, 15-20 parts of lotus root powder, 30-50 parts of gallnut, 10-20 parts of honeysuckle, 10-20 parts of pandan beans, 10-20 parts of propolis, 5-8 parts of oak bark, 5-10 parts of tea leaves, 3-5 parts of asarum, 1-2 parts of bighead atractylodes rhizomes and 5-30 parts of chlorhexidine acetate. The pharmaceutical composition for treating the oral ulcer has the effects of clearing away heat and toxic materials, eliminating stasis and diminishing swelling, promoting tissue regeneration and relieving pain, and inhibiting and killing bacteria, is quick in effects, easy in raw material finding and low in cost, and has a good treatment effect when being clinically used for treating the oral ulcer.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical compositions, in particular to a pharmaceutical composition for treating oral ulcers, a preparation method and application thereof. Background technique [0002] Oral ulcers, also known as aphthous ulcers, are the most common oral mucosal diseases. They refer to small and shallow defects or ulcers formed on the oral mucosa such as the tongue, cheeks, lips, gums, and soft palate due to various factors. Most oral ulcers are round or oval, with white or yellow centers and red edges. When oral ulcers attack, the pain is severe and there is a burning sensation in the local area, which affects eating and speaking. The prevalence rate of the general population can be as high as 20%, but the main cause of the disease has not yet been determined. Traditional Chinese medicine believes that oral ulcers are mostly caused by fire. [0003] According to investigations, the curative effect of currently ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K9/06A61P1/02A61K35/64A61K35/644A61K31/155
CPCA61K36/62A61K35/64A61K36/355A61K36/896A61K35/644A61K36/49A61K36/82A61K36/268A61K36/284A61K31/155A61K36/539A61K36/718A61K36/756A61K9/06A61K9/006A61K9/0063A61K47/02A61P1/02A61K2236/15A61K2236/333A61K2236/39A61K2300/00A61P17/02A61K36/898A61K36/22A61K36/185
Inventor 王崇福王葵高宇
Owner SICHUAN TIANFU FINE CHEM CO LTD
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