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Solid gastrodia elata consciousness-restoring traditional Chinese medicine composition as well as preparation method and application thereof

A technology of composition and traditional Chinese medicine, which is applied in the direction of drug combination, medical preparations containing active ingredients, medical formula, etc., can solve the problems of Tianma Xingnao Capsule improvement, achieve good social and economic benefits, rich sources of raw materials, medicine less toxic effect

Pending Publication Date: 2021-11-30
YUNNAN YONGZITANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this invention does not substantially improve the internal quality of Tianma Xingnao Capsules (Z20027062) such as biological effects

Method used

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  • Solid gastrodia elata consciousness-restoring traditional Chinese medicine composition as well as preparation method and application thereof
  • Solid gastrodia elata consciousness-restoring traditional Chinese medicine composition as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Example 1: Preparation of Tianma Xingnao Capsules

[0041] (1) Take 300 grams of Gastrodia elata, dry and pulverize to 100 mesh fine powder, and set aside.

[0042] (2) Wash 200 grams of Dilong, air dry, pulverize, add 60% ethanol to soak for 72 hours, filter, and use filtrate A for later use.

[0043] (3) Wash 300 grams of calamus, 200 grams of Polygala, 100 grams of Rehmannia glutinosa and 100 grams of Cistanche, soaked in 8 times the amount of water for 30 minutes, decocted for 1.5 hours, and filtered; then add 4 times the amount of water and decocted 1 hour, filter; combine the two filtrates, concentrate to a relative density of 1.10~1.05 (90°C), cool to room temperature, add ethanol to make the ethanol content reach 60%, stand for 45~50 hours, filter, filtrate B use;

[0044] (4) merging the filtrate A described in step (2) and the filtrate B described in step (3), reclaiming ethanol, and the obtained medicinal liquid is for use; adding the fine powder of Gastro...

Embodiment 2

[0045] Example 2: Preparation of Tianma Xingnao Capsules

[0046] The proportion of raw materials: 300 grams of Tianma, 200 grams of Dilong, 300 grams of Shichangpu, 200 grams of Polygala, 100 grams of Rehmannia glutinosa and 100 grams of Cistanche.

[0047] Method:

[0048] (1) Gastrodia elata is crushed into fine powder, sieved (passing a 100-mesh sieve), for use;

[0049] (2) Dilong is cold soaked in ethanol (60% ethanol) for 60 to 80 hours (72 hours), filtered to obtain filtrate A for subsequent use;

[0050] (3) Shichangpu, Polygala, Rehmannia glutinosa and Cistanche are boiled twice with water, the first time with water (8 times the amount of water) and boiled for 1.5 hours, the second time with water (4 times the amount of water) and boiled for 1 hour, divided into Filter, combine the filtrates, concentrate to a clear paste with a relative density of 1.10-1.15 (90° C.), cool, add ethanol to make the alcohol content reach 60%, stand for 48 hours, and filter to obtain...

Embodiment 3

[0053] Example 3: Preparation of Tianma Xingnao Capsules

[0054] Raw material ratio: 200 grams of Tianma, 250 grams of Dilong, 200 grams of Shichangpu, 250 grams of Polygala, 50 grams of Rehmannia glutinosa and 150 grams of Cistanche.

[0055] Method:

[0056] (1) Gastrodia elata is crushed into fine powder, sieved (passing a 100-mesh sieve), for use;

[0057] (2) Dilong was cold soaked in ethanol (50% ethanol) for 80 hours, filtered to obtain filtrate A for subsequent use;

[0058] (3) Shichangpu, Polygala, Rehmannia glutinosa, Cistanche cistanche are boiled twice with water, for the first time, add water (7 times the amount of water) and cook for 2 hours, and for the second time, add water (5 times the amount of water) and cook for 1.5 hours. Filter, combine the filtrates, concentrate to a clear paste with a relative density of 1.10-1.15 (90° C.), cool, add ethanol to make the alcohol content reach 60%, stand for 24 hours, and filter to obtain filtrate B for subsequent ...

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Abstract

The invention relates to a solid gastrodia elata consciousness-restoring traditional Chinese medicine composition as well as a preparation method and application thereof. Specifically, the composition is prepared from the following raw material medicines in parts by weight: 200 to 400 parts of gastrodia elata, 150 to 250 parts of earthworm, 200 to 400 parts of rhizoma acori graminei, 150 to 250 parts of polygala tenuifolia, 50 to 150 parts of prepared rehmannia root and 50 to 150 parts of cistanche. The invention further provides a preparation method of the traditional Chinese medicine composition and pharmaceutical application of the traditional Chinese medicine composition. The traditional Chinese medicine composition can be used for treating or preventing hypomnesis and slow response, treating or preventing encephalatrophy and treating or preventing cerebral dementia caused by stroke or cerebral trauma.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and relates to a traditional Chinese medicine composition comprising Gastrodia elata, Dilong, Shichangpu, Polygala Radix, Rehmannia glutinosa and Cistanche, in particular to a solid containing Tianma, Dilong, Shichangpu, Polygala, Rehmannia glutinosa and Cistanche The traditional Chinese medicine composition of Tianma Xingnao, also relates to the preparation method of the composition and their use. Background technique [0002] Brain atrophy, senile dementia and other diseases are diseases of brain dysfunction, mental decline, social activity decline, and changes in personality and behavior in the elderly. It is a chronic, progressive, and mental decline disease. It is a worldwide medical problem. Its pathology is atrophy of the cerebral cortex, also related to genetic factors, characterized by slow onset, overall impairment of brain function, intellectual deterioration, and accompani...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8988A61P25/28A61K35/62
CPCA61K36/8988A61K35/62A61K36/888A61K36/69A61K36/804A61K36/64A61P25/28A61K2236/331A61K2236/39A61K2236/55A61K2300/00
Inventor 刘令安刘正清杨华杨扬
Owner YUNNAN YONGZITANG PHARMA
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