Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Methods of purifying allergen extract

A technology for allergens and extracts, applied in the field of purifying allergen extracts, can solve the problems of allergic reactions or allergies of sensitized patients by injection of allergens

Pending Publication Date: 2021-12-21
莱蒂生物制药公司
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] One of the risks of immunotherapy is that injecting allergens into sensitized patients can cause anaphylaxis, or anaphylaxis

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Methods of purifying allergen extract
  • Methods of purifying allergen extract
  • Methods of purifying allergen extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0032] The allergen extracts of the present invention are derived from any source material comprising natural allergens known to elicit an IgE-mediated immune response in an individual. Such allergens may include airborne allergens (such as pollens from grasses, trees, herbs and weeds, dust mites, fungi and molds), food allergens (such as peanuts), insect allergens (such as from cockroaches and fleas, and bee and hornwort venoms) and epithelial allergens (animal hair and animal dander, such as cat and dog dander).

[0033] The source material can be any allergen, including food allergens (such as peanuts), airborne allergens (such as pollen (such as tree pollen, weed pollen, grass pollen, and cereal pollen), dust mites, fungi, and molds), epithelial allergens (animal hair and animal dander, eg, cat hair and dander and dog hair and dander), and insect allergens (eg, from cockroaches and fleas, and bee and wasp venom).

[0034] Pollen allergens from trees, grasses and weeds are...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to processes for producing semi-purified and purified allergen extracts and pharmaceutical compositions and vaccines for use in the diagnosis and treatment of allergy. In one aspect of the invention, a process for producing a depigmented allergen extract is provided, the process comprising: a) basifying a native allergen extract; and b) removing molecules having a molecular size of less than 3.5 kDa; and c) adjusting the pH to neutrality; thereby to produce a depigmented allergen extract.

Description

technical field [0001] The present invention relates to methods for the production of semi-purified and purified allergen extracts as well as pharmaceutical compositions and vaccines for the diagnosis and treatment of allergies. Background technique [0002] Allergies are acquired hypersensitivity disorders of the immune system and are triggered by exposure to innocuous environmental substances called allergens. Type I hypersensitivity is the hallmark of allergic reactions and results in the production of excess IgE antibodies, which activate basophils and mast cells, causing an inflammatory response. Effects may be systemic, such as vasodilation, mucus secretion, nerve stimulation, or smooth muscle contraction, leading to an allergic reaction, or effects may be limited to specific areas of the body, such as the respiratory system. [0003] Phleum pratense [0004] Grass allergy is one of the most common and prevalent forms of allergy affecting sensitive people during cert...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/35A61K35/646A61K35/36A61K35/68
CPCA61K35/35A61K35/36A61K35/646A61K35/68A61K36/63A61K36/899
Inventor M·罗曼·埃斯库蒂亚M·莫拉莱斯M·T·加列戈J·卡内尔·桑切斯
Owner 莱蒂生物制药公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com