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Traditional Chinese medicine composition for inhibiting oral infection of helicobacter pylori

A technology of Helicobacter pylori and composition, which is applied in the field of traditional Chinese medicine preparations, can solve the problems of complex ingredients, slow effect, high cost, etc., and achieve the effects of simple prescription, lower recurrence rate, and faster healing

Active Publication Date: 2022-03-08
HENAN HEGUIHENG IND CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are common deficiencies such as complicated ingredients, high cost, easy recurrence, and slow effect

Method used

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  • Traditional Chinese medicine composition for inhibiting oral infection of helicobacter pylori
  • Traditional Chinese medicine composition for inhibiting oral infection of helicobacter pylori
  • Traditional Chinese medicine composition for inhibiting oral infection of helicobacter pylori

Examples

Experimental program
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Effect test

Embodiment 1

[0021] The traditional Chinese medicine preparation for inhibiting oral infection of Helicobacter pylori comprises the following active ingredients, each component is by mass percentage:

[0022] Mucosa bactericidal factor compound chlorinated quaternary ammonium compound 0.005-0.18%

[0023] Chuanxiong extract 0.1-0.5%;

[0024] Huai Di Huang Extract 0.1-2.0%.

[0025] The balance is water and auxiliary materials.

[0026] Preparation method of Huai Di Huang extract: powder Huai Di Huang medicinal material, add 10 times the amount of water, reflux extraction 3 times, each time for 1.5 hours, combine extracts, decolorize, and concentrate under reduced pressure to obtain Huai Di Huang distilled stock solution.

[0027] The mucosal bactericidal factor compounded chlorinated quaternary ammonium compound is formed by compounding dodecyl dimethyl benzyl ammonium chloride and dioctyl dimethyl ammonium chloride at a mass ratio of 1:1.

[0028] Suspension quantitative experiment: ...

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Abstract

The invention belongs to the technical field of traditional Chinese medicine preparations, discloses a traditional Chinese medicine composition for inhibiting oral infection of helicobacter pylori, and particularly relates to a traditional Chinese medicine preparation containing a Huai radix rehmanniae extract and used for killing oral infection of helicobacter pylori. Comprising the following effective components in percentage by mass: 0.005-0.18% of mucous membrane bactericidal factor compounded chlorine type quaternary ammonium salt and the balance of water, 0.1 to 0.5 percent of ligusticum wallichii extract; 0.1%-2.0% of a rehmannia glutinosa extract; and the balance of water and auxiliary materials. The composition can be prepared into oral spray or toothpaste additive. All the components have a synergistic effect, helicobacter pylori in the oral cavity can be efficiently killed, the sterilization rate is 99.99%, meanwhile, the oral mucosa is repaired, and the ecological balance of the oral cavity is maintained. The traditional Chinese medicine composition can treat ulcer and also has the effect of treating halitosis.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and relates to an antibacterial agent for oral cavity, in particular to a traditional Chinese medicine preparation containing Huai Dihuang extract and used for efficiently killing Helicobacter pylori infection in oral cavity. Background technique [0002] Helicobacter pylori (Helicobacter priori, H pylori) is a spiral Gram-negative microaerophilic curved bacterium with flagella. The stomach is the main residence of H. pylori, and most gastrointestinal diseases are caused by Helicobacter pylori infection. caused by. In recent years, researchers have also detected H.pylori from oral dental plaque, saliva, mucosal tissue, and vomit, and studies have shown that oral H.pylori is related to the occurrence of various oral diseases, including recurrent oral ulcers, halitosis, Periodontitis, dental caries, etc. The H.pylori in the patient's mouth was consistent with the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61P31/04A61P31/02A61P1/02A61P7/04A61K8/9789A61K8/41A61Q11/00A61K31/14
CPCA61K36/236A61K36/804A61K31/14A61P31/04A61P31/02A61P1/02A61P7/04A61K8/9789A61K8/416A61Q11/00A61K2236/331A61K2236/39A61K2236/51A61K2300/00Y02A50/30
Inventor 程贵昌张一帆程伯恒
Owner HENAN HEGUIHENG IND CO LTD
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