31results about How to "No teratogenicity" patented technology

The present invention discloses a kind of indoor air smell-cleaning agent, including two portions of component A and component B. The compount A is a solid active agent formed from one or several kinds of oxalic acid, tartaric acid, amino acid, citric acid, aminosulfonic acid, isonicotinic acid and camphoric acid, and the component B is a stable solution formed from one or several kinds of potassium chlorate, sodium chlorate, magnesium chlorate, sodium hypochlorite, calcium hypochlorite, sodium chlorite, sodium perchlorate, potassium perchlorate, sodium dichloroisocyanurate and sodium trichloroisocyanurate. The component A can be added in the component B. The substances of nascent state oxygen, nascent state chlorine or chlorinedioxide can be released so as to eliminate harmful smell pollution due to building, decoration and furniture in the room.

The invention discloses low-smoke low-halogen flame-retardant conveyor belt covering glue for a coal mine, and relates to the technical field of conveyor belt covering glue. The covering glue comprises the following chemical components: natural standard rubber, styrene-butadiene rubber SBR1502, cis-butyl BR9000 rubber, polyisobutylene PB1300, an anti-aging agent, zinc oxide, magnesium oxide, stearic acid, a flow release agent, N234 carbon black, nano-aluminum hydroxide, antimony trioxide, decabromodiphenylethane, composite ceramic powder, expanded halogen-free flame-retardant IFR, a multi-purpose synergistic halogen-free flame retardant PNA220, molybdenum salt used as a smoke suppressant, an accelerator and sulfur. The low-smoke low-halogen flame-retardant conveyor belt covering glue disclosed by the invention is used under a coal mine well to meet flame-retardant performance of the conveyor belt, has excellent wear resistance and flame retardancy, and is low in smoke amount and smoketoxicity.

The invention provides an anal fistula biological suppository and a preparation method thereof. The anal fistula biological suppository uses small intestine submucosa tissues of inbred line animals without cell and DNA (deoxyribonucleic acid) components as the raw material, completely reserves the extracellular matrix component and structure, and has a micropore structure. The preparation method of the anal fistula biological suppository comprises the following operation steps: determination of animal source, pretreatment and rough cleaning of small intestine tissues, virus inactivation, cell removal, DNA removal treatment, formation, packaging and sterilization. The anal fistula biological suppository prepared by the method uses an inbred line animal as an animal source, and thus, the hereditary features are pure, stable and uniform, thereby radically ensuring the stability and uniformity of different batches of products; and the anal fistula biological suppository has fewer animal source DNA residues, completely reserves the three-dimensional structure of natural ECM, and has the advantages of low immune source property and high infection resistance.

The invention discloses a nosiheptide-colistin sulfate premixed agent which comprises 0.5-4 portions of nosiheptide, 1-10 portions of colistin, and the carriers of calcium carbonate, zeolite powder, corn flour, etc. for the rest in every 100 weight portions. The preparation method is as following. The raw materials are added in a mixing machine by the sequence of the carriers, the colistin sulfate, the nosiheptide and the carriers, and mixed evenly to make into powdery nosiheptide-colistin sulfate premixed agent. Or the nosiheptide and the carriers can be mixed fully firstly, then the colistin sulfate is dissolved in the water and sprinkled evenly on the mixture of the nosiheptide and the carriers. After being granulated, dried and screened, the mixture is made into the granular-typed nosiheptide-colistin sulfate premixed agent, the granularity of which is 30-60 mesh. The nosiheptide-colistin sulfate premixed agent of the invention is added in feedstuffs. The content range of the nosiheptide in every kilogram of overhead price feedstuff is 0.5-20mg, and the content range of the colistin sulfate in every kilogram of overhead price feedstuff is 2-40mg.

The invention relates to aqueous chlorhexidine iodine sterilizing spray and a preparation method thereof. The spray comprises the following materials by weight: 0.1-2% of chlorhexidine iodine, 1-30% of solubilizer, 0.5-5% of cosolvent and the balance of water, and is prepared by dissolving the chlorhexidine iodine, the solubilizer and the coslovent with appropriate amount of water under ultrasonic treatment, adding the rest of water until the sum of the prescription is 100%, mixing, and filling into a spray bottle. The inventive spray has the advantages of no iodine odor, yellow-staining, toxicity, teratogenecity and skin/mucous membrane irritation, low available concentration, strong sterilizing ability, wide antibacterial spectrum, simple preparation process, and easy popularization.

The invention discloses a novel wound self-healing biological material, a preparation method and application thereof, and relates to the technical field of biological materials. The wound self-healing biological material comprises a solid component and a liquid component, wherein the solid component comprises a cationic water-soluble chitin derivative which is a chitin derivative soluble in purified water, and accounts for 0.1 to 100 weight percent of the total weight of solid component. The novel wound self-healing biological material has the advantages that the structure and performance of a molecular scaffold of the cationic water-soluble chitin derivative is close to those of skin and mucosal intercellular matrix mucopolysaccharide (such as hyaluronic acid), and is an excellent matrix material for the growth of skin and mucosal cells, and the self-healing of human skin and mucosal injury is promoted effectively by the antibiotic property of cationic macromolecules.

The invention relates to a beauty composition containing a vaccinium vitis-idaea extract and application thereof to skin beauty. The invention provides the vaccinium vitis-idaea extract, which contains components of anthocyanin, procyanidin, resveratrol and polyphenols such as catechin and the like. The invention also relates to the application of the vaccinium vitis-idaea extract to the beauty, including but not limited whitening, color fleck removing, wrinkle removing, skin smoothness strengthening, and skin sensitivity improving. The invention also discloses a medicament, the beauty composition and food which are prepared from the vaccinium vitis-idaea extract. Compared with the prior cosmetics, the vaccinium vitis-idaea extract has better effect and higher safety.

The invention relates to the technical field of natural rubber primary processing, and in particular relates to an ammonia-free preservative for natural fresh latex. An oxidation-type bactericide is selected from a large amount of solid, water-soluble, non-volatile and broad-spectrum bactericides aiming at pollution problems of ammonia and ammonia composite preservatives, and the oxidation-type bactericide is compounded with an alkaline stabilizer to be used as a preservation system of the natural latex. The novel preservation system provided by the invention has the characteristics of a goodpreservation effect, low costs, no ammonia, no volatilization, no irritation, easy solubility in water and convenient use, and can preserve the natural latex for a plurality of days, and the preparedraw rubber has excellent properties, especially has significantly-improved aging resistance; and in addition, the preservative can also be applied to early-stage preservation in the ammonia-free concentrated latex preparation process, and the overall costs are lower than those of a currently-used ammonia and TT/ZnO systems.

The invention discloses an ultramicro traditional Chinese medicine for preventing and treating lactation reduction and redness and swelling of breasts of dairy cows. The ultramicro traditional Chinese medicine comprises raw materials in parts by weight as follows: 25-32 parts of dandelions, 18-22 parts of weeping forsythia, 15-25 parts of baical skullcap root, 25-34 parts of cowherb seeds, 18-22 parts of beautiful sweetgum fruits, 8-13 parts of uniflower swisscentaury root, 18-22 parts of Chinese angelica, 8-13 parts of rhizoma chuanxiong, 6-11 parts of bighead atractylodes rhizome, 9-14 parts of frankincense, 6-12 parts of myrrh and 8-11 parts of Chinese honeylocust spines. The ultramicro traditional Chinese medicine has the functions of treating both symptoms and root causes, and can be used for directly inhibiting or killing pathogenic bacteria of mastitis or inhibiting or killing pathogenic bacteria through improvement of body immunity; the medicine formula adopts the principles of heat and toxic material clearing, antisepsis, anti-inflammation, menstrual flow promotion, blood circulation promotion, swelling and pain elimination, collateral activation and lactation promotion, has functions of tonifying qi, raising yang and strengthening body resistance to dispel pathogenic factors, is effective and has a high cure rate, the milk quality of the dairy cows is improved, and the milk amount is remarkably increased. The ultramicro traditional Chinese medicine has controllable quality and the drug dependence is eliminated.

The invention discloses a leather cleansing agent. The leather cleansing agent is prepared from the following raw materials in parts by weight: 35-56 parts of deionized water, 12-16 parts of natural saponin, 4-7 parts of sodium polystyrene sulfonate, 4-8 parts of alcohol ethoxylate carboxylate, 1-3 parts of ethylene glycol monostearate, 3-7 parts of sophorolipids, 18-22 parts of a cross-linking agent, 5-10 parts of a cross-linking monomer, 7-9 parts of soybean ethylsulfuric acid ethyl ester morpholine, 5-9 parts of hydroxyethyl cellulose, 22-25 parts of ethanediol, 5-8 parts of a surface active agent, and 1-6 parts of castor oil butyl oleate sodium sulphate. The leather cleansing agent disclosed by the invention is free from odour, has light delicately-fragrant flavour, is free from irritability when being in contact with skin, free from teratogenicity and free from potential carcinogenicity, and does not corrode natural leather.

The invention discloses an antimicrobial moldproof finishing agent for rabbit-hair fabric. The finishing agent is prepared from, by weight, 5-6 parts of sodium polystyrenesulfonate, 3-6 parts of hydroxypropyl xanthan gum, 10-14 parts of emulsifier, 12-16 parts of natural saponins, 5-10 parts of sophorolipid, 3-6 parts of epoxy chloropropane, 5-8 parts of ethyltriethoxysilane, 15-20 parts of 2-methyl-4-isothiazoline-3-ketone, 11-14 parts of dibutyltin dilaurate, 16-22 parts of coupling agent, 1-8 parts of glycerin, 4-8 parts of crosslinking monomers, 8-10 parts of alkylphenol polyoxyethylene and 40-50 parts of deionized water. By means of the antimicrobial moldproof finishing agent for the rabbit-hair fabric, the functions of mold prevention, anti-microbial, deodorization and the like can be given to the rabbit-hair fabric, and the finishing agent is free of irritation to skin, free of allergic reaction and free of toxicity, teratogenicity and potential carcinogenicity and meets the environment-friendly requirement.

The invention belongs to the technical field of traditional Chinese medicine preparations, discloses a traditional Chinese medicine composition for inhibiting oral infection of helicobacter pylori, and particularly relates to a traditional Chinese medicine preparation containing a Huai radix rehmanniae extract and used for killing oral infection of helicobacter pylori. Comprising the following effective components in percentage by mass: 0.005-0.18% of mucous membrane bactericidal factor compounded chlorine type quaternary ammonium salt and the balance of water, 0.1 to 0.5 percent of ligusticum wallichii extract; 0.1%-2.0% of a rehmannia glutinosa extract; and the balance of water and auxiliary materials. The composition can be prepared into oral spray or toothpaste additive. All the components have a synergistic effect, helicobacter pylori in the oral cavity can be efficiently killed, the sterilization rate is 99.99%, meanwhile, the oral mucosa is repaired, and the ecological balance of the oral cavity is maintained. The traditional Chinese medicine composition can treat ulcer and also has the effect of treating halitosis.

The invention discloses a hot spring sanitary wet tissue formula. The hot spring sanitary wet tissue formula comprises the following main components: a piece of non-woven fabric, and wet tissue solution, wherein the wet tissue solution comprises 99% of hot spring water, 0.5% of herbal enzyme and 0.5% of PHMB. According to the hot spring sanitary wet tissue formula in the invention, due to comprehensive compatibility of the components, such as the hot spring water, the herbal enzymes and the PHMB, the effects of promoting skin blood circulation, improving metabolism and killing bacteria are achieved; and thus, the hot spring sanitary wet tissue formula in the invention has the advantages of being high in functionality, capable of improving metabolism and capable of achieving sterilization.

The invention provides a 3D printing resin for antibacterial wear-resistant shoes. The 3D printing resin is applied to the field of 3D printing. The 3D printing resin comprises the following raw materials in parts by weight: 20-40 parts of carboxyl-terminated butadiene modified acrylate, 10-30 parts of fluoroalkane modified acrylate monomers, 10-15 parts of a reactive diluent, 1-2 parts of a polymerization inhibitor, 2-3 parts of a photoinitiator, 3-5 parts of a pigment, 10-15 parts of a filler, 0.5-2 parts of an antibacterial finishing agent and 5-10 parts of a silane coupling agent. According to the obtained 3D printing resin for the antibacterial and wear-resistant shoes, the resin is compounded with high elasticity and wear resistance required by shoe materials, meanwhile, the antibacterial property requirement is met, and the 3D printing resin can be used in the field of 3D printing shoes.

The invention provides a Tpl2-deficient MDCK cell strain as well as a construction method and application thereof, and relates to the technical field of biology. In the MDCK cell strain, 239th to 243rd bases of a first exon of a Tpl2 gene are deleted. The Tpl2 gene in the MDCK cell strain is knocked out through frame shift mutation, but the mutation has no influence on the growth rate and cell morphology of an MDCK cell after passage for 10 generations; tests show that the Tpl2-deficient MDCK cell strain provided by the invention can be stably inherited, is safe and reliable, and solves the problem that an existing mutant MDCK cell is unstable or unsafe in heredity. The Tpl2-deficient MDCK cell strain disclosed by the invention can be used for improving the flu virus yield after being inoculated with flu viruses, and compared with conventional MDCK cell culture, the supernatant hemagglutination titer and the supernatant virus TCID50 titer are obviously improved, and the problem of insufficient flu virus yield in the existing MDCK cell culture is solved.

The invention relates to a biochemical detection reagent box. The reagent box comprises a reagent A, a reagent B and a reagent C, wherein the reagent A is a SDS/[C2mim][BF4] compound reaction solution, the reagent B is color rendering substrate 3,3'5,5'-tetramethyl benzidine (TMB) solid powder, and the reagent C is a H2O2 solution. According to needs, the reagent box further comprises a reagent D, a reagent E and a reagent F, wherein the reagent D is HRP enzyme liquid, the reagent E is a buffer solution PBS, and the reagent F is a substrate solvent dimethyl sulfoxide (DMSO-d6, 99.9%). According to the reagent box, on the basis of the principle that the SDS/[C2mim][BF4] compound reaction solution can significantly improve the color rendering efficiency of HRP-H2O2-TMB reaction, and the synergism effect is adopted to achieve HRP enzyme activity determination and H2O2 concentration detection. The reagent box has the advantages of being quick, sensitive and stable in color rendering, reagent organisms for detection are non-toxic, the operation is quick and convenient, the cost is low, and the reagent box has commercial potential for large-scale HRP activity determination and H2O2 concentration detection.