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Preparation method of cold heat-clearing tablets

A cold-clearing and traditional Chinese medicine technology, applied in the field of traditional Chinese medicine, can solve the problems of low recovery rate of active ingredients, easy loss of heat-sensitive ingredients, high extraction temperature, etc., and achieve the effect of short concentration time, more absorption and low concentration temperature

Pending Publication Date: 2022-04-12
河北唐威药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Chinese medicine uses the decoction method to extract the active ingredients of medicinal materials. In the preparation process of traditional Chinese medicine, there are generally disadvantages such as long extraction time, high extraction temperature, high energy consumption, easy loss of heat-sensitive ingredients, low recovery rate of active ingredients, and troublesome post-processing.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] (1) Weigh 365g Nepeta panicle, 105g mint, 180g Fangfeng, 180g Bupleurum, 105g perilla leaf, 180g kudzu root, 105g bellflower, 140g bitter almond, 105g Angelica dahurica, 365g Kudiding, and 290g reed rhizome;

[0020] (2) Take the nepeta panicles, peppermint, and perilla leaves of the above weight, add 8 times the quality water of the above-mentioned three traditional Chinese medicines, distill and extract the volatile oil for 1.0 hour, and collect the distilled aqueous solution in another device; For the first time, add water with 8 times the quality of the above-mentioned eleven traditional Chinese medicines for the first time, decoct for 1.0 hour, filter to obtain the filtrate; add water with 6 times the quality of the above-mentioned eleven traditional Chinese medicines to the filtered residue, decoct for 1.0 hour, filter to obtain the filtrate; The two filtrates are combined with the distilled aqueous solution;

[0021] (3) The combined decoction is concentrated und...

Embodiment 2

[0023] (1) Weigh 375g of Schizonepetae, 113g of Peppermint, 188g of Fangfeng, 113g of Bupleurum, 113g of Perilla Leaf, 188g of Pueraria Radix, 113g of Campanulaceae, 150g of Bitter Almond, 113g of Angelica Dahurica, 375g of Kudiding and 300g of Reed Rhizome;

[0024] (2) Take the nepeta panicles, peppermint, and perilla leaves of the above weight, add 10 times the quality water of the above-mentioned three traditional Chinese medicines, distill and extract the volatile oil for 2 hours, and collect the distilled aqueous solution in another device; For the first time, add 10 times the quality water of the above-mentioned eleven traditional Chinese medicines for the first time, decoct for 1 hour, filter to obtain the filtrate; add 8 times the quality of the above-mentioned eleven traditional Chinese medicines to the filter residue, decoct for 1 hour, filter to obtain the filtrate; The two filtrates are combined with the distilled aqueous solution;

[0025] (3) The combined soluti...

Embodiment 3

[0027] (1) Weigh 385g Nepeta panicle, 120g mint, 195g Fangfeng, 195g Bupleurum, 120g perilla leaf, 195g kudzu root, 120g bellflower, 160g bitter almond, 120g Angelica dahurica, 385g Kudiding, and 310g reed rhizome;

[0028] (2)) Take the Nepeta panicle, peppermint and perilla leaves of the above weight, add 12 times the quality water of the above-mentioned three traditional Chinese medicines, distill and extract the volatile oil for 2 hours, and collect the distilled aqueous solution in another container; add water to decoct the dregs and the remaining eight herbs For the second time, add 12 times the quality water of the above-mentioned eleven traditional Chinese medicines for the first time, decoct for 2.0 hours, filter to obtain the filtrate; add 10 times the quality of the above-mentioned eleven traditional Chinese medicines to the filter residue, decoct for 2 hours, filter to obtain the filtrate ; Twice the filtrate is combined with the distilled aqueous solution;

[0029...

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Abstract

The invention discloses a preparation method of a cold heat-clearing tablet. The preparation method comprises the following steps: (1) weighing raw materials; (2) taking schizonepeta spike, mint and perilla leaf, adding water which is 8-12 times of the mass of the three traditional Chinese medicines, distilling to extract volatile oil for 1.0-2.0 hours, and collecting the distilled water solution in another container; adding water into decoction dregs and other medicines, decocting twice, adding water which is 8-12 times of the mass of all the traditional Chinese medicines in the step (1) for the first time, decocting for 1.0-2.0 hours, and filtering to obtain filtrate; after filtering, adding water which is 6-10 times of the mass of all the traditional Chinese medicines in the step (1) into filter residues, decocting for 1.0-2.0 hours, and filtering to obtain filtrate; combining the two filtrates with the distilled aqueous solution; and (3) combining the decoctions, concentrating under reduced pressure, adding auxiliary materials, granulating, spraying the volatile oil in the step (2), and pressing into tablets, or coating with a film coating or a sugar coating to obtain the cold and heat clearing tablets. The method is low in extraction temperature, low in energy consumption, short in extraction time, small in heat-sensitive component loss and high in effective component recovery rate.

Description

[0001] This application is a divisional application with an application date of January 13, 2017, an application number of 201710024030.X, and an invention title of "A Preparation Method for Ganmao Qingre Tablet". technical field [0002] The invention relates to the technical field of traditional Chinese medicine, in particular to a preparation method of Ganmao Qingre Tablet. Background technique [0003] Flu is a common disease affecting the health of patients, which can lead to poor mental state of patients, and has a great impact on life and work. Cold is also a kind of acute infectious rhinitis, commonly known as "cold". It is caused by respiratory viruses, among which coronavirus and rhinovirus are the main pathogenic viruses. The virus is excreted and spread from respiratory secretions. When the body's resistance decreases, such as cold, malnutrition, excessive fatigue, excessive smoking and alcohol, systemic diseases, and chronic diseases of the nose itself that aff...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K9/20A61K9/28A61P11/00
CPCA61K36/899A61K9/2059A61K9/2806A61K9/2826A61K36/232A61K36/233A61K36/238A61K36/346A61K36/488A61K36/534A61K36/535A61K36/538A61K36/66A61K36/736A61K2236/39A61K2236/51A61K2236/331A61K2300/00
Inventor 李宗悟
Owner 河北唐威药业有限公司
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