Traditional Chinese medicine granules for relieving cough and reducing sputum and preparation method thereof

A technology of traditional Chinese medicine granules, relieving cough and reducing phlegm, which is applied in the field of medicine, and can solve problems such as turbidity of the solution, and achieve the effect of clear solution, no burnt debris, and a slightly sweet taste

Pending Publication Date: 2022-07-15
广西中医药大学附属瑞康医院 +1
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The Zhideke granule prepared by this method has the highest comprehensive score in terms of molding rate, hygroscopicity, fluidity, and solubility. However, when the solubility is checked with hot water at 70-80°C, the solution is turbid.

Method used

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  • Traditional Chinese medicine granules for relieving cough and reducing sputum and preparation method thereof

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preparation example Construction

[0034] 1. A preparation method of an aqueous extract of Chinese medicinal granules for relieving cough and resolving phlegm, comprising the following steps:

[0035] T1. respectively take by weight 120kg of Longan leaf, Shegan 120kg, Platycodon grandiflorum 120kg, Baiqianqian 120kg, Scutellaria baicalensis 75kg, Qingtiankui 75kg, Loquat leaf 120kg, Bupleurum 120kg, Peppermint 75kg, Nepeta 75kg;

[0036] T2. Add 5 times the amount of water to mint and Nepeta, soak for 30 minutes, extract by distillation for 3 hours, and collect volatile oil for later use;

[0037] T3. filter the water extract after distillation to obtain the water extract, and the residue is for subsequent use;

[0038] T4. Add 12 times of water to the residue and other eight medicinal materials, soak for 50 minutes, decocted for 3 times, 1 hour each time, filter, and combine the filtrate with the above water extract to obtain the water extract of Chinese medicine granules for relieving cough and resolving phle...

Embodiment 1

[0078] The preparation method of Chinese medicine granules for relieving cough and resolving phlegm comprises the following steps:

[0079] T1. respectively take by weight the leaves 10kg of Longan, Shegan 10kg, Platycodon grandiflorum 10kg, Baiqianqian 10kg, Scutellaria baicalensis 6.5kg, Qingtiankui 6.5kg, Loquat leaf 10kg, Bupleurum 10kg, Peppermint 6.5kg, Nepeta 6.5kg;

[0080] T2. Add 5 times the amount of water to mint and Nepeta, soak for 30 minutes, extract by distillation for 3 hours, and collect volatile oil for later use;

[0081] T3. filter the water extract after distillation to obtain the water extract, and the residue is for subsequent use;

[0082] T4. Add 12 times of water to the residue and other eight herbs, soak for 50 minutes, decoct 3 times, 1 hour each time, filter, combine the filtrate and the above water extract, and let stand at 4°C for 24 hours;

[0083] T5. Take the supernatant by microfiltration through a ceramic membrane with a membrane pore size...

Embodiment 2

[0087] The preparation method of Chinese medicine granules for relieving cough and resolving phlegm comprises the following steps:

[0088] T1. respectively take by weight 13kg of Longan leaf, 13kg of Shegan, 13kg of Platycodon grandiflorum, 13kg of Baiqianqian, 8.5kg of Scutellaria baicalensis, 8.5kg of Scutellaria japonica, 13kg of loquat leaf, 13kg of Bupleurum chinensis, 8.5kg of Peppermint, 8.5kg of Nepeta mustard;

[0089] T2. Add 5 times the amount of water to mint and Nepeta, soak for 30 minutes, extract by distillation for 3 hours, and collect volatile oil for later use;

[0090] T3. filter the water extract after distillation to obtain the water extract, and the residue is for subsequent use;

[0091] T4. Add 12 times of water to the residue and other eight medicinal materials, soak for 50 minutes, decocted for 3 times, 1 hour each time, filter, combine the filtrate and the above water extract, and let stand at 10°C for 48 hours;

[0092] T5. Take the supernatant by...

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Abstract

According to the method, the preparation process of the granules is further improved through the methods of low-temperature standing of a water extract, ceramic membrane microfiltration of supernate, granulation by adding a dispersing agent and the like. The traditional Chinese medicine granules for relieving cough and reducing sputum provided by the invention are good in flowability, not easy to absorb moisture and damp, particularly easy to disperse and dissolve, good in dissolubility, clear in solution, free of scorched scraps, precipitates and turbid phenomena, slightly sweet in taste and convenient to drink and carry; the traditional Chinese medicine composition has the effects of dispelling wind, clearing heat, relieving cough, reducing sputum and relieving sore-throat, and can be used for treating acute and chronic tracheobronchitis, upper respiratory infection, pneumonia, acute pharyngitis and other wind-heat invading lung patients.

Description

technical field [0001] The invention belongs to the field of medicines, and in particular relates to a traditional Chinese medicine granule for relieving cough and resolving phlegm and a preparation method thereof. Background technique [0002] Zhide Ke Fang is a clinical experience formula of Ruikang Hospital Affiliated to Guangxi University of Traditional Chinese Medicine. The formula has the functions of dispelling wind and clearing heat, relieving cough and resolving phlegm, and phlegm, and can be used to treat acute and chronic tracheo-bronchitis, upper respiratory tract infection, pneumonia, acute pharyngitis and other wind-heat invading lungs. Zhideke recipe is used in clinical practice in the form of decoction, but the decoction has shortcomings such as troublesome decoction, poor taste, not easy to carry and store, etc., which affects the medication compliance of patients. The present invention intends to make this recipe suitable for industrial production. And the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61K47/69A61K9/16A61K47/36A61P11/00A61P11/04A61P11/10A61P11/14
CPCA61K36/47A61K36/88A61K36/346A61K36/27A61K36/539A61K36/898A61K36/73A61K36/233A61K36/534A61K36/538A61K47/6951A61K9/1652A61P11/00A61P11/04A61P11/10A61P11/14A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 梁洁陈日兰唐友明姜枫谢谭芳黄秋洁
Owner 广西中医药大学附属瑞康医院
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