Application of Nano copper powder for preparing medicine for prophylaxis of osteoporosis and bone fracture

A nano-copper powder, osteoporosis technology, applied in drug combination, powder delivery, bone diseases, etc., can solve the problems of calcium and phosphorus cannot be deposited, poor absorption, and difficult to last the curative effect

Inactive Publication Date: 2006-01-04
马驷 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of the current clinical calcium supplements are not well absorbed or calcium and phosphorus cannot be deposited in the bones after absorption.
Estrogen replacement therapy can directly improve bone metabolism in postmenopausal women and effectively prevent the progressive loss of bone in the first few years after menopause. However, short-term use of estrogen can hardly last long, and long-term use can easily lead to various complications, such as breast cancer. Cancer, endometrial cancer and other serious complications

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach 1

[0105] Embodiment one preparation tablet

[0106] Take the following steps: take the nano-copper powder, adopt a conventional tablet-making process, add a dry binder and a lubricant, mix evenly, directly compress into tablets, and coat with sugar to obtain tablets, so that each tablet contains 2.5 mg of nano-copper powder .

[0107] Usage and dosage: Take orally, one tablet at a time, twice a day.

Embodiment approach 2

[0108] Embodiment 2 Preparation of Capsules

[0109] The following steps are adopted: take the nanometer copper powder, sieve it, add starch and mix it evenly, divide it into hard capsules to prepare capsules, and each capsule contains 2.5 mg of the nanometer copper powder.

[0110] Dosage: Take orally, one tablet at a time, twice a day.

Embodiment approach 3

[0111] Embodiment 3 Preparation of granules

[0112] The following steps are taken: take nano-copper powder, add excipients powdered sugar and starch, sieve to make soft material, granulate, dry at low temperature, granulate, pack into bags to obtain granules, each bag contains nano-copper The powder is 2.5mg. Usage and dosage: Take it with warm boiled water, one bag at a time, twice a day.

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PUM

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Abstract

An application of nano (0.1-1000 nm) copper powder in preparing the medicines to prevent and treat osteoporosis and bone fracture is disclosed. Its advantages are sure curative effect and low toxic by-effect.

Description

technical field [0001] The invention relates to the application of nanometer copper powder as a medicine for the prevention and treatment of osteoporosis and fracture. Background technique [0002] At present, osteoporosis is a systemic skeletal disease characterized by decreased bone mass and degeneration of bone microstructure, resulting in increased bone fragility and susceptibility to fracture. With the increase of the elderly population, osteoporosis may become the health enemy of most people in the future, so this high incidence and metabolic bone disease is one of the difficult problems that the medical field is currently studying. Osteoporosis is mainly divided into two categories: primary and secondary. Primary osteoporosis is a physiological change in bone tissue due to aging or postmenopausal women. Osteoporosis induced by malnutrition and drugs due to certain diseases (such as endocrine disorders, chronic diseases such as kidney, liver and gastrointestinal calci...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K33/34A61P19/10A61K9/14A61K45/06A61P19/08
CPCA61K45/06A61K9/14A61K33/34A61P19/08A61P19/10
Inventor 马驷李艳
Owner 马驷
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