Unlock instant, AI-driven research and patent intelligence for your innovation.

Probe of fiber optic chemical sensor

A chemical sensor and optical fiber technology, applied in the determination of the dissolution rate or release rate of solid pharmaceutical preparations, optical fiber chemical sensor probes, and the determination of components in blood, can solve filter clogging, easily generate air bubbles and cleaning workload, which has not been realized in the field Bit real-time monitoring and other issues to achieve the effect of avoiding blockage

Inactive Publication Date: 2006-10-04
新疆富科思生物技术发展有限公司
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it does not realize on-site real-time monitoring, and there are problems such as easy blockage of the filter, adsorption of trace drugs, easy generation of air bubbles, and heavy cleaning workload after measurement.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Probe of fiber optic chemical sensor
  • Probe of fiber optic chemical sensor
  • Probe of fiber optic chemical sensor

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Embodiment 1, as attached figure 1 As shown, the optical fiber chemical sensor probe includes a jacket 1, an optical fiber 2 and a sensitive film 3, and the detection end 4 of the optical fiber is equipped with a sensitive film 3, and the length of the optical fiber 2 is 25 cm to 250 cm, and the diameter is 10.0 μm to 2500 μm. It is necessary to determine the specific length and diameter, which is suitable for a miniature optical fiber chemical sensor probe.

Embodiment 2

[0022] Embodiment 2, as attached figure 2 As shown, the optical fiber chemical sensor probe includes a casing 5, an optical fiber 2 and a reflector 6, the detection end 4 of the optical fiber is installed on the inner end 7 of the casing 5, and a reflector 6 is installed on the outer end 8 of the casing 5 , there is a sample inlet 11 in the middle part 10 of the casing 5, the length of the optical fiber 2 is 25cm to 250cm, and the diameter is 0.1cm to 2.50cm, and the specific length and diameter are also determined according to actual needs; as attached figure 2 As shown, according to the determination of the dissolution or release of different solid pharmaceutical preparations, optical fiber chemical sensor probes with different optical paths are manufactured, which are especially suitable for the dissolution or release of specific solid pharmaceutical preparations (tablets, capsules, etc.) It is suitable for making a specific type of optical fiber chemical sensor probe.

Embodiment 3

[0023] Embodiment 3, as attached figure 2 and 3 As shown, the difference between embodiment 3 and embodiment 2 is that there are two sample inlets 11 in the middle part 10 of the casing 5 .

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
lengthaaaaaaaaaa
diameteraaaaaaaaaa
diameteraaaaaaaaaa
Login to View More

Abstract

The fiber chemical sensor probe includes jacket layer, fiber and sensing film in the detecting end of the fiber; or, includes casing with at least one sample inlet in the middle part, fiber and reflector installed in the outer end of the casing; or includes casing, fiber and reflector, which is installed inside the light path regulating rod screwed or inserted to the outer end of the casing. The present invention may be used for in-situ monitoring of liquid or gas matter, especially in the measurement of the leaching degree or releasing degree of solid medicine and the measurement of blood components. It may be produced into different forms, and the light source may be ultraviolet, visible or infrared absorbing, reflecting or other light source.

Description

1. Technical field: [0001] The invention relates to a probe for measuring the properties of liquid or gas substances using an optical fiber chemical sensor. Applied to the determination of blood components. 2. Background technology: [0002] "Determination of dissolution or release rate of solid pharmaceutical preparations (tablets, capsules, etc.)" is a necessary item for drug identification all over the world. The determination of drug dissolution is essential in improving the quality of pharmaceutical preparations and developing new dosage forms. The application of the dissolution method is firstly the quality control of conventional drugs; secondly, the quality evaluation after the process change or the pilot scale-up of the preparation; thirdly, the basis for exempting the bioequivalence test of the new specification; in addition, for controlling the quality of the drug preparation Design and screening, calculation of dosage and course of treatment, all play a very im...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): G01N21/75
Inventor 熊海江李新霞陈坚刘欢
Owner 新疆富科思生物技术发展有限公司