Indometacin eyedrops
A technology of indomethacin and eye drops, applied in sensory diseases, anti-infective drugs, drug combinations, etc., can solve problems such as retention, systemic side effects, and less obvious curative effects, and achieve inhibition of cyclooxygenase activity and release Inflammatory effect, the effect of simple production method
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[0007] Examples of parts by weight of the raw materials included in the present invention are: indomethacin 40, polyethylene glycol-4003200, sodium sulfite 8, borax 48, boric acid 176, and water for injection 8000.
[0008] The molecular formula of indomethacin of the present invention is: C 19 H 16 CINO 4
[0009] The shape of the present invention is: a light yellow clear liquid with a PH value of 6.5 to 8.5.
[0010] The production method of the embodiment of the present invention is as follows: A. Weighing: accurately weigh indomethacin, sodium sulfite, borax, and boric acid into the above-mentioned parts by weight using a prescribed scale or balance, and put them in a clean container for later use; B. Preparation :Take a heavy part of water for injection 8000 and place it in a clean ingredient tank (1), add sodium sulfite 8, borax 48, and boric acid 176 by weight while stirring, fully dissolve it, seal it, and boil it in water at 100°C for 30 minutes. , Cool to room temperat...
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