Emergency protective agent for wound

A protective agent and wound technology, applied in the direction of aerosol delivery, skin diseases, nitrile/isonitrile active ingredients, etc., can solve the problems of wound hemostasis and sterile coverage that are difficult to effectively solve

Active Publication Date: 2004-09-01
FOURTH MILITARY MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] During the on-site first aid process of a large number of wounded caused by wartime firearm injuries, serious traffic injuries in peacetime, emergency rescue, mountaineering expeditions, landslides, typhoons, earthquakes, mudslides and other natural disasters, the problems of hemostasis and sterile coverage of wounds have been difficult to effectively solve.
However, the application in trauma wound treatment is only found in the replacement of surgical sutures to bond wound margins to close wounds, and there are no reports of hemostasis, temporary coverage of wounds, and other wound protection in trauma wound fire lines or pre-hospital first aid.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0054] Get α-cyanoacrylate alkyl ester pure monomer 50 grams (wherein α-cyanoacrylate ethyl ester pure monomer accounts for 80% weight, α-cyanoacrylate propyl ester pure monomer accounts for 20% weight), strengthen 2.7 grams of polyvinyl acetate and 0.6 grams of toughening agent butyl cyanoacetate are mixed uniformly in a stirring device, and then 20 grams of environmentally friendly propellant dimethyl ether are taken, and the mixture of propellant dimethyl ether and the above-mentioned obtained Fill into an aerosol bottle. A sunken wound with a diameter of 10 cm was made on the buttocks of the domestic pig, deep enough to reach the muscle layer, and a large amount of blood oozes from the wound as seen. Rapidly and continuously spray the wound first-aid protective agent of the present invention for 10 seconds, the bleeding of the wound stops in 7 seconds after spraying, the surface is covered by the film formed by the sprayed protective agent liquid, and the protective agent ...

Embodiment 2

[0056] Get α-cyanoacrylate alkyl ester pure monomer 70 grams (wherein α-cyanoacrylate ethyl ester pure monomer accounts for 50% weight, α-cyanoacrylate propyl ester and α-cyanoacrylate butyl ester pure monomer Each accounts for 25% by weight), 6.0 grams of reinforcing agent neoprene rubber and 2.0 grams of toughening agent dibutyl phthalate are mixed uniformly in a stirring device, and then environment-friendly propellant 1, 1, 1, 2-4 Fluoroethane (HFC-134a) 35 grams, the propellant HFC-134a and the mixture obtained above are filled into the aerosol bottle according to the conventional process. A wound with a diameter of 6 cm was made on the inner side of the domestic pig's thigh, reaching deep into the muscle layer to expose the femoral artery. Cut off 1 / 2 of the diameter of the femoral artery, see blood spurt. Quickly put a tourniquet on the proximal end of the wound, wipe off the wound blood with gauze, and spray the protective agent on the wound continuously for about 10 ...

Embodiment 3

[0058] Get α-cyanoacrylate alkyl ester pure monomer 60 grams (wherein α-cyanoacrylate ethyl ester pure monomer accounts for 50% weight, α-cyanoacrylate propyl ester, α-cyanoacrylate butyl ester pure monomer Respectively account for 30%, 20% by weight), 4.5 grams of reinforcing agent styrene-butadiene rubber and 1.5 grams of toughening agent dibutyl sebacate are mixed uniformly in a stirring device, and then 25 grams of environment-friendly propellant dimethyl ether are taken, press The conventional process fills the propellant dimethyl ether and the mixture obtained above into an aerosol bottle. A wound with a diameter of 6 cm was made on the inner side of the domestic pig's thigh, reaching deep into the muscle layer to expose the femoral artery. Cut off 1 / 2 of the diameter of the femoral artery, see blood spurt. Quickly put a tourniquet on the proximal end of the wound, wipe off the wound blood with gauze, and spray the protective agent on the wound continuously for about 10...

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PUM

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Abstract

The invention discloses a wound first-aid protecting agent the percentage by weight of the ingredients of which are, alpha-cyanacrylate alkyl 50-70 parts, intensifier 2.5-6.5 parts, flexibilizer 0.5-2.5 parts, environment-friendly type casting agent 15-40 parts. The invention can be applied for effectively stopping artery and venous hemorrhage in limb wound.

Description

technical field [0001] The invention relates to a first-aid protection agent for wounds, which is used in the field of self-rescue and mutual rescue of the wounded in wartime and the field of emergency medicine in peacetime, including the wounded caused by war wounds, traffic injuries, emergency rescue, mountaineering expeditions, earthquakes, typhoons, landslides, mudslides and other natural disasters Limbs or trunk surface bleeding wounds for fire or pre-hospital first aid, especially suitable for wartime, can be used for both military and civilian purposes. Background technique [0002] In the on-site first aid process of a large number of wounded caused by wartime firearm injuries, serious traffic injuries in normal times, emergency rescue, mountaineering expeditions, landslides, typhoons, earthquakes, mudslides and other natural disasters, it has been difficult to effectively solve the problems of wound bleeding and sterile coverage. One of the main difficulties is the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/12A61K31/275A61P17/02
Inventor 裴国献
Owner FOURTH MILITARY MEDICAL UNIVERSITY
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