Medicine for treating chronic nephritis and its preparing process

A chronic nephritis and drug technology, which is applied in the direction of drug combination, medical formula, medical preparations containing active ingredients, etc., can solve the problems of unacceptable by patients and expensive medical expenses, and achieve the improvement of decreased urine output, reduced urinary protein, and reduced Effect of BUN and Cr values

Inactive Publication Date: 2004-11-17
湖北省医药工业研究院有限公司
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  • Abstract
  • Description
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  • Application Information

AI Technical Summary

Problems solved by technology

However, medical expenses are expe

Method used

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Examples

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Effect test

preparation example Construction

[0125] Preparation of the extract of Prunus chinensis: cut into sections, decoct with water for 2 to 3 times, each time for 0.5 to 1.5 hours, combine the decoction, filter, heat the filtrate to evaporate water and concentrate to 1% of the weight of the crude drug. / 2~1 / 4, add ethanol to precipitate, let stand, filter, wash, recover ethanol, concentrate to thick paste, dry under reduced pressure at 60℃~80℃, dry and pulverize into fine powder;

[0126] Preparation of Scutellaria baicalensis extract: Scutellaria baicalensis, decoction slices, add water and decoct 3-4 times, 0.5-1 hour each time, combine the decoction, filter, add hydrochloric acid to the filtrate, adjust pH 1-2, keep warm at 75-85°C for 1-3 hour, stand still, suction filter the precipitate, wash with water, dry, dry and pulverize into fine powder;

[0127] Preparation of Shiwei extract: chop Shiwei, add water and decoct 2-3 times, 0.5-1.5 hours each time, combine the decoction, filter, heat the filtrate to evapor...

Embodiment 1

[0130] Components: 2674g of Prunus chinensis, 297g of Scutellaria baicalensis, 475g of Shiwei, 475g of Astragalus membranaceus, 891g of soluble starch, 891g of dextrin, and 59g of stevioside.

[0131] Preparation method: Preparation of the extract of Prunus chinensis: cut into sections, add water and decoct 2 to 3 times, each time for 0.5 to 1.5 hours, combine the decoction, filter, heat the filtrate to evaporate the water and concentrate to the crude drug 1 / 2 to 1 / 4 of the weight, add ethanol to precipitate, let stand, filter, wash, recover ethanol, concentrate to a thick paste, dry under reduced pressure at 60°C to 80°C, dry and pulverize into fine powder;

[0132]Preparation of Scutellaria baicalensis extract: Scutellaria baicalensis, drink slices, add water and decoct 3-4 times, 0.5-1 hour each time, combine the decoction, filter, add hydrochloric acid to the filtrate, adjust pH 1-2, keep warm at 75°C for 3 hours, let it stand , suction filtered the precipitate, washed wit...

Embodiment 2

[0137] Components: 2674g of Prunus chinensis, 297g of Scutellaria baicalensis, 475g of Shiwei, 1188g of astragalus, 6534g of lactose, and 6534g of mannitol.

[0138] Preparation method: the preparation of the extract of Prunus chinensis: the same as in Example 1;

[0139] Preparation of Scutellaria baicalensis extract: Scutellaria baicalensis, drink slices, add water and decoct 3 to 4 times, 0.5 to 1 hour each time, combine the decoction, filter, add hydrochloric acid to the filtrate, adjust pH 1 to 2, keep warm at 80°C for 2 hours, and let it stand , suction filtered the precipitate, washed with water, dried, dried and pulverized into fine powder;

[0140] Preparation of Shiwei extract: same as Example 1;

[0141] Preparation of Radix Astragali Extract: Same as Example 1.

[0142] With the fine powder of 4 kinds of extracts, mix, take lactose, mannitol, mix, make granule, dry, make 1000g, pack separately, obtain the granule for treating chronic nephritis of the present inve...

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Abstract

The invention relates to a traditional Chinese medicinal composition for treating chronic nephritis which is prepared from 45-65 wt% of bicolor lespedeza, 5-15 wt% of baikal skullcap root, 8-20 wt% of shiwei, 8-20 wt% of astragalus root through the steps of extracting, alcohol deposition, decompression, condensing, and drying.

Description

technical field [0001] The invention relates to a medicine for treating chronic nephritis and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] Chronic nephritis is a common and frequently-occurring disease. According to relevant epidemiological survey statistics, the incidence of glomerular disease in my country is about 0.2-4%. The number of patients is relatively large, especially in people with poor living and working conditions. Adolescents account for more than 3 / 4 of the causes of chronic renal failure in my country. There is no substantial progress in the treatment of chronic nephritis at home and abroad. Most patients still rely on hormones, cyclophosphamide, indomethacin and other drugs to temporarily relieve pain, or apply hemodialysis and kidney transplantation to treat patients with renal insufficiency and uremia. However, medical expenses are expensive and difficult for patients to accept. Con...

Claims

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Application Information

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IPC IPC(8): A61K9/16A61K9/20A61K9/48A61P13/12
Inventor 杨红武史自东杨惠芳吴佳毛衍平
Owner 湖北省医药工业研究院有限公司
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