32results about How to "Decreased urine output" patented technology

The present invention discloses clerodendranthus spiatus extract for treating urinary calculus and its preparation process, and belongs to the field of Chinese herbal medicine extract and application technology. The clerodendranthus spiatus extract preparing process includes the following steps: soaking clerodendranthus spiatus in 4-10 times methanol to extract and concentrating to obtain extractum; dissolving the extractum in solvent in the same volume; extracting the solution first with petroleum ether and then with ethyl acetate and concentrating to obtain coarse extract; and chromatographic separation, eluting, collecting and concentrating to operate clerodendranthus spiatus extract A. The clerodendranthus spiatus extract A is liposoluble flavone glycoside compound and has obvious urinary calculus treating effects.

The invention relates to a traditional Chinese medicine composition, especially a traditional Chinese medicine composition for treating chronic nephritis, composed of the following raw materials by weight: astragalus root 15g, achyranthes root 15g, mulberry bark 10g, moutan bark 15g, dried rehmannia root 12g, ginseng 10g, tuckahoe 10g, cornel 15g, pinellia 10g, medlar 12g, caterpillar fungus 10g, atractylodes rhizome 12g, wofberry bark 20g, ledebouriella root 15g, tortoise plastron 12g, Chinese yam 20g, glycyrrhizae 5g. The traditional Chinese medicine composition has obvious effect on treating chronic nephritis, with high curative rate and great clinical generalization value.

The hypoglycemic Chinese yam milk powder is used for preventing and treating diabetes. It is prepared with Chinese yam 60-80 weight portions, defatted milk powder 15-20 weight portions, and xylitol 5-10 weight portions. The Chinese yam milk powder is taken after being mixed with boiled water and has the functions of reducing blood fat, strengthening disease resistance and delaying senility and has obvious effect of preventing and treating diabetes.

The present invention discloses a clerodendranthus spicatus extract capable of resisting urinary lithiasis and its preparation method, belonging to the field of Chinese medicinal material extract and application technology. Said method includes the following several steps: (1), mixing clerodendranthus spicatus and methyl alcohol according to the ratio of weight: volume=1:4-10, soaking, extracting and concentrating to obtain extract mixture; (2), mixing said extract mixture and dissolving liquor according to the ratio of weight:volume=1:1, dissolving; (3), firstly, using petroleum ether to extract the dissolved liquor, then using ethyl acetate to make secondary extraction, concentrating so as to obtain extract; and (4), making above-mentioned obtained extract undergo the processes of chromatography, elution, collection and concentration so as to obtain the invented cleodendranthus spicatus extract component A. Said cleodendranthus spicatus extract component A belongs to a fat-soluble flavone aglucone compound, said compound can be used for preparing the medicine with the functions of improving litholysis, promoting lithecbole, diuresis and relieving inflammation, etc.

The present invention discloses a clerodendranthus spicatus extract for resisting urinary lithiasis and its preparation method, belonging to the field of Chinese medicinal material extract and application technology. Said method includes the following steps: (1), soaking the cleodendranthus spicatus and methyl alcohol according to the ratio of weight:volume=1:4-10, extracting and concentrating so as to obtain extract mixture; (2), mixing said extract mixture and dissolving liquor according to the ratio of weight:volume=1:1 and dissolving; (3), firstly, using petroleum ether to extract said dissolved liquor, then using ethyl acetate to make secondary extraction, concentrating to obtain extract; and (4), making the above-mentioned obtained extract undergo the processes of chromatography, elution, collection and concentration so as to obtain the invented cleodendranthus spicatus extract component A. Said component A belongs to a fat-soluble flavone aglucone compound which can be used for preparing the medicine with the excellent effect for improving litholysis, promoting lithecbole, diuresis and relieving inflammation, etc.

The invention discloses an internal medicine for treating chronic nephritis, which is prepared from the following Chinese herbal medicines: prepared rehmannia root, aweto, ginseng, rhizoma alismatis,wolfberry fruit, white atractylodes rhizome, ambergris, tortoise shell, human nail, radix notoginseng, polyporus umbellatus, cinnamon, Chinese angelica root, cassia twig, white peony root, semen coicis, moghania philippinensis, avicennia pricklyash root, plantain seed, rhizoma imperatae, costus root, raw hawthorn and chicken's gizzard-membrane. The medicine has the advantages of obvious effect, convenient administration, and no toxic and side effects. For chronic nephritis, the effective rate is 89%, and the cure rate is 80%.

The invention relates to a traditional Chinese medicine composite as well as a product and an application of the traditional Chinese medicine composite. The composite comprises the following traditional Chinese medicine raw materials in parts by weight: 20-40 parts of Astragalus mongholicus and 10-20 parts of mulberry and also comprises one or several of the following traditional Chinese medicine raw materials in parts by weight: 5-15 parts of salviae miltiorrhizae, 5-15 parts of angelica sinensis, 10-20 parts of processed fleece-flower root, 5-15 parts of rhizoma chuanxiong and 1-5 parts of pseudo-ginseng. The traditional Chinese medicine composite has better actions on lowering sugar, lowering fat, improving a blood rheology index, reducing urine protein or improving the creatinine clearance rate and especially has the actions on protecting the vascular endothelial cell, alleviating the damage degree of the endarterium and the like, and therefore the traditional Chinese medicine composite can be prepared into oral administration or external application products used for treating or controlling renal damage, neuropathy around limbs, high blood fat, impotence, prostatic hyperplasia, diabetes mellitus and complications, such as diabetic foot, diabetic nephropathy and diabetic retinal inflammation, and has good protecting action on the liver, the kidney, the pancreas and the intestinal mucosa.

The present invention belongs to the field of medicine, and particularly relates to uses of cycloastragenol in preparation of chronic renal failure treatment drugs. According to the present invention, cycloastragenol is the aglycone of astragaloside A, and has advantages in biological membrane permeation and gastrointestinal tract absorption compared to astragaloside A due to the relatively small molecular weight and the strong lipophilicity, and the test results show that cycloastragenol can change various physiologic indexes of chronic renal failure rates so as to provide great application prospects in the treatment of chronic renal failure.

The invention discloses a kidney tea anti-urinary calculus extract and a preparation method thereof, and belongs to the technical field of extracts and applications of Chinese herbal medicines. The method comprises: (1) soaking, extracting, and concentrating kidney tea and methanol at a weight: volume ratio of 1:4 to 10 to obtain an extract mixture; 1 proportion mixing and dissolving; (3) Extract the solution with petroleum ether first, then extract with ethyl acetate and concentrate to obtain the extract; (4) Chromatography, elute, collect and concentrate the extract to obtain the kidney tea extract Material A component. It is a fat-soluble flavonoid aglycone compound, which can significantly improve the symptoms of urinary stones, reduce the amount of stones, increase urine output, help stone discharge and anti-inflammatory effects. It can be directly, compounded or further separated and extracted, and can be used for anti-calculus, stone expulsion, diuretic and anti-inflammatory drugs in the urinary system.

The invention discloses a medicine for treating chronic nephritis, and belongs to the field of traditional Chinese medicines. The medicine is prepared from the following raw materials by weight: 20 g of astragalus membranaceus, 15 g of fructus kochiae, 15 g of angelica sinensis, 15 g of rhizoma atractylodis macrocephalae, 15 g of fructus lycii, 15 g of radix stephaniae tetrandrae, 15 g of pericarpium arecae, 15 g of monkshood, 15 g of ligusticum wallichii, 15 g of prepared rhizome of rehmannia, 15 g of eucommia ulmoides, 15 g of cornus officinalis, 15 g of the root of bidentate achyranthes, 10 g of cordyceps sinensis, 10 g of donkey-hide gelatin, 10 g of wolfiporia extensa, 10g of herba taxilli, 10 g of ephedra sinica stapf, 10 g of stiff silkworms, 10 g of cortex mori, 5 g of cortex cinnamomi, and 5 g of liquorice. The medicine for treating chronic nephritis has the effects of tonifying qi and yin, warming the kidney, inducing dieresis, replenishing qi to invigorate the spleen, and nourishing yin for suppressing hyperactive yang, is accurate in curative effect, produces an instant effect, and causes no toxic or side effects.

The invention relates to an application of tea to preparation of medicines for relieving polyuria symptoms caused by diabetes, and discloses the tea which can quickly, strongly and durably improve thepolyuria symptoms of patients suffering from diabetes. The mechanism of the application lies in that the tea can notably increase the expression amount of kidney protein kinase C, aquaporin or urea transport protein of the patients suffering from polyuria, and can promote the membrane shift of the kidney protein kinase C, the aquaporin or the urea transport protein, so that the reabsorption capacity of kidney to water is reinforced, the micturition is reduced, and the blood sugar is reduced. The invention provides a new policy for effective improvement of the polyuria symptoms of the patientssuffering from diabetes, and reducing blood sugar.

The invention belongs to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating septic shock and accompanying multi-organ dysfunction syndrome. The traditional Chinese medicine composition is prepared from the combination of red ginseng, radix aconiti lateralis preparata, ligusticum wallichii, salvia miltiorrhiza, pulsatilla chinensis, radix aucklandiae, radix ophiopogonis and crocus sativus which synergistically act to play the effects of effectively clearing heat and removing toxicity, strengthening healthy energy and tonifying Qi, and promoting blood circulation to remove blood stasis so as to reach the purpose of treating septic shock and accompanying multi-organ dysfunction syndrome. The traditional Chinese medicine composition is accurate in treatment effect, free of toxic and side effects, outstanding in treatment effect and high in potential clinical application value, and reaches total effective rate exceeding 85.00%.

The invention relates to a traditional Chinese medicine composition for treating the uremia, and belongs to the technical field of traditional Chinese medicine preparing. The composition comprises orally-taken medicine and external application medicine. The orally-taken medicine comprises, by weight, 3 parts to 8 parts of first-class ginseng, 3 parts to 8 parts of semen plantaginis, 3 parts to 8 parts of capillary artemisia, 3 parts to 8 parts of herba cistanche, 3 parts to 8 parts of mulberries, 3 parts to 8 parts of fructus psoraleae, 5 parts to 10 parts of lalang grass rhizomes, 5 parts to 10 parts of semen cuscutae, 5 parts to 15 parts of lophatherum gracile, 5 parts to 10 parts of bighead atractylodes rhizomes, 10 parts to 20 parts of raw radix astragalis and 10 parts to 30 parts of fried sticky rice. The external application medicine comprises, by weight, 50 parts to 80 parts of raw garlic and 20 parts to 50 parts of mirabilite. The preparing method of the orally-taken medicine includes the steps that refluxing is carried out on the traditional Chinese medicinal materials with the weight parts through ethyl alcohol with the volume ten times that of the traditional Chinese medicinal materials, and extracting, separating and drying are carried out for standby application. The preparing method of the external application medicine includes the step that the traditional Chinese medicinal materials with the weight parts are mixed in proportion to be mashed to be pasty for standby application. According to the traditional Chinese medicine composition, oral taking and external application are combined; after continuous taking is carried out, the functions of clearing away heat, cooling blood, eliminating toxins, warming and activating meridians and promoting blood circulation to remove blood stasis are achieved, fibrosis of kidney tissues is relieved, the kidney functions are gradually restored finally, and the curing effect is achieved.

The invention discloses novel fermented Lactobacillus and applications of the novel fermented Lactobacillus in the fields of feeds and sewage treatment, and belongs to the field of microorganisms. According to the present invention, the novel fermented Lactobacillus is Lactobacillus Fermentum strain LBF128, has characteristics of acid resistance, salt tolerance and high-temperature resistance, canbe propagated under anaerobic, aerobic and facultative conditions, and can survive for more than 2 h under the pH value of 2.0, wherein more than 70% of the live bacteria can reach the intestine after the novel fermented Lactobacillus passes through the stomach due to the breeding under the anaerobic, aerobic and facultative conditions; the novel fermented Lactobacillus can be used as the additive for livestock and poultry feeds, and can further be used for the biological deodorization of manure, wherein the effect is stable, and the pollutants (COD of more than 25000) in the original manure)can be degraded to below 1500; and the novel fermented Lactobacillus can be used for the treatment of domestic sewage, acidic high-salt sewage and river basin sewage, has advantages of good acid resistance, good salt resistance, high survival rate and significant treatment effect, and can survive and work in the environment with the salt content of up to 6%.

The invention provides a hellgrammites extract for treating chronic renal failure as well as a preparation method and application of the hellgrammites extract. The preparation method sequentially comprises the following steps: (1) washing chellgrammites with ultrapure water, performing draining, and performing cryopreserving at the temperature of-80 DEG C; (2) freeze-drying the frozen hellgrammites obtained in the step (1) at-80 DEG C, and then adding liquid nitrogen for grinding to obtain dry hellgrammites powder; and (3) adding an isopyknic 75 vt% ethanol solution into the hellgrammites dry powder obtained in the step (2), performing reflux extraction for 2-3 hours each time for 4-6 times, combining extracting solutions, and performing freeze drying to obtain the hellgrammites extract for treating the chronic renal failure. The invention also discloses the hellgrammites extract prepared by the method and application of the hellgrammites extract in preparation of medicines for treating chronic renal failure. The corydalus cornutus extract is applied to treatment of the chronic renal failure, and various symptoms caused by the chronic renal failure can be effectively treated.

The invention discloses a traditional Chinese medicine composition for treating chronic cough and a preparation method thereof. The traditional Chinese medicine composition for treating chronic coughis prepared through the following raw materials: liquorice, rhizoma zingiberis, schisandra chinensis and cartialgenous. The traditional Chinese medicine composition for treating chronic cough is prepared by screening a large number of medical components; recombining; and testing; and the traditional Chinese medicine composition for treating chronic cough is prepared through traditional Chinese medicinal materials, so that a patient is safe to take and does not need antibiotic; the patient avoids antibiotics resistance; the traditional Chinese medicine composition has the functions of eliminating phlegm by cooling, alleviating mental depression, eliminating stagnation, dispelling the wind and relieving a cough, and is capable of strengthening the mechanism of the human body, and improving the immunity and the disease resistance and is outstanding in effect of treating chronic cough.

A nutritive non-saccharide albumen liquid for preventing and controlling obesity, cardiovascular and cerebrovascular diseases, fatigue syndrome and diabetes is prepared from whole albumen of quail egg, lactic acid, citric acid, malic acid, acetic acid, and rebaudioside through acidic-alkaline hydrolysis to a whole albumen of quasil egg, proportionally adding others, filter and sterilizing. Its advantages are high effect, less damage to nutrients, and long storage period.

A Chinese medicine for treating chronic nephritis and chronic renale failure is prepared from 14 Chinese-medicinal materials including Philippine flemingia root, cordyceps, red ginseng fleece flower root, etc through pulverizing 3 of them, extracting from others in water and depositing in alcohol to obtain their extract, mixing the powder with the extract, stirring, drying, and mixing it with carrier.

The invention discloses traditional Chinese medicine composition for treating chronic nephritis and an application. The traditional Chinese medicine composition is prepared from traditional Chinese medicine raw materials as follows: amur corktree bark, densefruit pittany root-bark, common dayflower herb, mosla scabra, common achyranthes herb, Chinese knotweed herb, wintersweet flower, pubescent holly root, caenopteris japonica thunb., glabrous greenbrier rhizome, root of common triumfetta, panax pseudo-ginseng, astragalus membranaceus, hawthorn fruit, endothelium corneum gigeriae galli and liquorice. The traditional Chinese medicine composition has the advantages that a patient suffering from chronic nephritis can be quickly healed, the recovery rate is high, the effect is remarkable, the effective rate is up to 96%, and the cure rate is up to 80%.

The hypoglycemic Chinese yam milk powder is used for preventing and treating diabetes. It is prepared with Chinese yam 60-80 weight portions, defatted milk powder 15-20 weight portions, and xylitol 5-10 weight portions. The Chinese yam milk powder is taken after being mixed with boiled water and has the functions of reducing blood fat, strengthening disease resistance and delaying senility and has obvious effect of preventing and treating diabetes.

The invention discloses an alpinia oxyphylla-radix lindera extract for treating nephropathy. The raw materials of the alpinia oxyphylla-radix lindera extract mainly includes the petroleum ether part of an alpinia oxyphylla extract and radix lindera; the alpinia oxyphylla-radix lindera extract mainly comprises alpinia oxyphylla volatile oil and radix lindera volatile oil. The preparation method of the alpinia oxyphylla-radix lindera extract for treating nephropathy comprises steps of alpinia oxyphylla pretreatment, layering treatment, extraction of volatile oil, cleaning of radix lindera tuberous roots, grinding, soaking, extracting through a distillation method, mixing and blending, and packaging. The preparation method of the alpinia oxyphylla-radix lindera extract for treating nephropathy disclosed by the invention can increase concentration of plasma CAMP in blood and is beneficial to phosphorylation of AQP2; and the alpinia oxyphylla-radix lindera extract is important for reduction of urine volume molecules of patients with kidney-yang deficiency and diuresis, is capable of increasing secretion of serum ALD in blood of patients, so as to achieve an effect of reducing urine volume.

A natural medicine for treating uremia is prepared from composite biologic mineral, collagen and 5 Chinese-medicinal materials including red sage root, rhubarb, epimedia, etc.

The invention belongs to the field of medicines, and particularly relates to a medicine for treating central diabetes insipidus and application thereof. The medicine for treating central diabetes insipidus comprises a compound shown in a formula (I) or a formula (II), and further comprises indapamide. The compound shown in the formula (I) or the formula (II) has good treatment function on the central diabetes insipidus, and can reach better treatment effect by combining with the indapamide; the safety is good. The medicine is preferably an oral tablet; the medical auxilari materials preferablycomprise lactose, pregelatinized starch, fine cellulose, hydroxypropyl cellulose and magnesium stearate.

The invention belongs to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating septic shock and accompanying multi-organ dysfunction syndrome. The traditional Chinese medicine composition is prepared from the combination of red ginseng, radix aconiti lateralis preparata, ligusticum wallichii, salvia miltiorrhiza, pulsatilla chinensis, radix aucklandiae, radix ophiopogonis and crocus sativus which synergistically act to play the effects of effectively clearing heat and removing toxicity, strengthening healthy energy and tonifying Qi, and promoting blood circulation to remove blood stasis so as to reach the purpose of treating septic shock and accompanying multi-organ dysfunction syndrome. The traditional Chinese medicine composition is accurate in treatment effect, free of toxic and side effects, outstanding in treatment effect and high in potential clinical application value, and reaches total effective rate exceeding 85.00%.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating anemia and a preparation method thereof. The traditional Chinese medicine composition comprises the following raw materials of radix angelicae sinensis, pericarpium citri reticulatae, radix astragali, rhizoma polygonati, Chinese wolfberry, red jujubes, fructus crataegi, lemons, an iron nutrition enhancer, folic acid compounds and sodium chloride. According to the invention, through scientific compatibility and reasonable proportioning of dosages in a prescription, while the anemia caused by various reasons is improved, the digestion and absorption of nutrient substances by the body can be promoted, the immunity of the body is improved, and the fatigue is relieved.

The invention discloses a novel fermenting lactobacillus and its application in the fields of feed and sewage treatment, belonging to the field of microorganisms. The novel fermenting Lactobacillus of the present invention is Lactobacillus Fermentum bacterial strain LBF128, has acid-resistant, salt-resistant, high-temperature-resistant performance, the characteristic that all can breed under anaerobic, aerobic and facultative state, under the condition of pH=2.0, still can Survive for more than 2 hours, and can reproduce under anaerobic, aerobic and facultative conditions, so it can keep more than 70% of live bacteria after passing through the stomach and reach the intestinal tract. It can be used as an additive for livestock and poultry feed, and can also be used for feces The biological deodorization has a stable effect, and can degrade the pollutants in the original feces and urine (COD above 25000) to below 1500; it can also be used for the treatment of domestic sewage, acidic high-salt sewage, and river basin sewage, with good acid and salt resistance , high survival rate, remarkable treatment effect, and can still survive and work in an environment with a salt content as high as 6%.