Application of BAPTA derivative in the preparing process of clinical medicine

A technology of derivatives and drugs, which is applied in the application field of BAPTA derivatives in the preparation of clinical drugs, can solve the problems of not being used in human body, no medicinal research of BAPTA derivatives, and unsolved key problems in pharmacy, so as to reduce the blood pressure of blood vessels. Permeability, inhibition of cerebral edema, and effect of reducing brain index
CN1605333AInactive Publication Date: 2005-04-13HENGXING PHARMA INST HEFEI
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Patent Information

Authority / Receiving Office
CN ยท China
Patent Type
Applications(China)
Current Assignee / Owner
HENGXING PHARMA INST HEFEI
Publication Date
2005-04-13
Estimated Expiration
Not applicable ยท inactive patent

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Abstract

The present invention features that BAPTA derivative is applied in preparing medicine for treating acute great area cell death clinically. The medicine is prepared into particle preparation for the clinical salvage and treatment of acute great area cell death diseases, such as cerebral infarction, myocardial infarction, liver necrosis, ischemic kidney necrosis, necrotic pencreatitis, etc.
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Description

1. Technical field

[0001] The present invention relates to a novel use of a derivative of a known compound, specifically the application of BAPTA and its derivatives in the preparation of clinical medicines. It is used for the rescue and treatment of patients with acute massive cell death. 2. Background technology

[0002] Ischemia and hypoxia are the main causes of acute mass cell death in the human body, such as ischemic stroke and myocardial infarction leading to the death of brain cells and cardiomyocytes. In recent years, the research on the mechanism of cell death related to ischemia and hypoxia has made great progress, which points out the direction and provides a theoretical basis for the research and development of powerful drugs to protect cells from death.

[0003] Mr. Zhang Juntian, a famous pharmacologist, discussed intracellular calcium overload in the book "Modern Pharmacological Experimental Methods" and pointed out that intracellular calcium overload caused...

Claims

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