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Medicine for treating radioactive membrana mucosa damage, repeative aphtha and paradentitis

A technology for recurrent aphthous ulcers and mucosal injuries, which is applied in the field of medicine and can solve problems such as the absence of wound healing medicines

Inactive Publication Date: 2005-05-18
HARBIN MEDICAL UNIVERSITY +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Oral topical drugs are rarely used to treat periodontitis, and there are no drugs that promote incision healing after oral surgery

Method used

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Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0004] Specific embodiment one: The composition of this embodiment includes superoxide dismutase and vitamin B at the same time 12 and vitamin B 2 , when the prepared product is an aerosol, the dosage of each component is: for every 20,000-100,000 units of superoxide dismutase, the vitamin B used 12 0.001-0.005 grams, vitamin B used 2 0.005-0.015 grams.

specific Embodiment approach 2

[0005] Specific embodiment two: the present embodiment contains the following ingredients: 75ml of distilled water, 15ml of glycerol, 10ml of absolute ethanol, 100ml in total as auxiliary materials, i.e. solvent; superoxide dismutase (SOD) 20000~100000 units, vitamin B 12 0.001~0.005g, vitamin B 2 0.005-0.015 grams, as the main ingredient, that is, the solute. Among the above components, the excipients are not simple water preparations. The ethanol in the components has antiseptic and antibacterial effects. Local application promotes blood circulation, which is conducive to drug penetration and exerts drug effects; Odor, good taste.

specific Embodiment approach 3

[0006] Specific embodiment three: the composition in the present embodiment is as follows: superoxide dismutase 40000 units, vitamin B 12 0.002g, Vitamin B 2 0.012 grams, 75ml of distilled water, 15ml of glycerin, 10ml of absolute ethanol.

[0007] It is produced by simply mixing all the ingredients in proportion. It can be put into a throat sprayer during use, and the specific use method is the same as the fourth embodiment below.

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PUM

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Abstract

The present invention relates to medicine, and is medicine for treating radioactive mucous membrane damage, recurrent aphtha and paradentitis. The medicine contains SOD, vitamin B12 and vitamin B2, and may be aerosol or oral lozenge. The aerosol product has the components of SOD 20000-100000 IU, vitamin B12 0.001-0.005 g and vitamin B2 0.005-0.015 g. The oral lozenge product has the components of SOD 1000-4000 IU, vitamin B12 0.000009-0.00009 g and vitamin B2 0.0002-0.0008 g. The medicine has wide material source, low cost, and other advantages.

Description

Technical field: [0001] The present invention relates to a medicine. Background technique: [0002] During radiation therapy for cancer patients, due to the action of reactive oxygen species, normal tissues can be damaged at the same time, causing systemic reactions, such as bone marrow suppression leading to decreased blood components, decreased white blood cells, red blood cells, and platelets, nausea, vomiting, and decreased physical fitness. Local normal tissues at the irradiated site may be damaged. For example, radiotherapy to the head and neck can lead to erosion, ulceration, or even necrosis of the oropharyngeal mucosa. Patients suffer from abnormal pain, and radiotherapy must be interrupted due to severe damage, which gives cancer cells a chance to breathe and accelerate reproliferation, which is not good for cancer control. During radiotherapy for thoracic tumors, the severity of radioactive esophagus in patients increases. In severe cases, the pain affects eating...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/12A61K38/44A61P1/02A61P17/16
Inventor 刘元华
Owner HARBIN MEDICAL UNIVERSITY
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